Picky proteins: Understanding yeast adaptor protein selectivity
The cellular membrane controls the passage of substances in and out of the cell. Some larger cargo, such as membrane proteins, nutrients, and pathogens, enter the cell via a process known as clathrin-mediated endocytosis......»»
Silicon metasurfaces unlock broad-spectrum infrared imaging
Infrared imaging technology is crucial for advancing our understanding of the world, from exploring biological specimens to inspecting complex materials and detecting hidden patterns in physical systems......»»
Employers" lack of understanding limiting job opportunities for people with learning disabilities, study finds
Employers' lack of understanding is limiting employment opportunities for job seekers with learning disabilities, a new study has found......»»
MicroRNA, Protein Folding and Machine-Learning Work Win the Science Nobels
A roundup of the science Nobels, the latest COVID updates and the Europa Clipper launch delay......»»
Fossil Human Ancestor ‘Lucy’ Remains Pivotal 50 Years after Discovery
Half a century after its discovery, this iconic fossil remains central to our understanding of human origins.....»»
What we can learn from animals about death and mortality
Susana Monsó chats with Ars about her new book, Playing Possum: How Animals Understand Death. Human beings live every day with the understanding of our own mortality, but do anim.....»»
Targeting bacteria: Auxiliary metabolic genes expand understanding of phages and their reprogramming strategy
Viruses that infect bacteria—known as bacteriophages—could be used in a targeted manner to combat bacterial diseases. They also play an important ecological role in global biogeochemical cycles. Recent research by researchers at the University of.....»»
Scientists discover chemical probes for previously "undruggable" cancer target
Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1). FOXA1 mutations can enable these types of cancers to grow and proliferate. Today, FOXA1 is notoriously diff.....»»
Canopy structure regulates autumn phenology by mediating microclimate in temperate forests, finds study
Autumn phenology serves as a sensitive indicator of temperate forests' response to climate change and is a key factor influencing forest carbon sequestration. Understanding the mechanisms driving the spatiotemporal variations in autumn phenology is c.....»»
Bacteria discovered in healthy vertebrate brains point to a potential role in brain function
Researchers at the University of New Mexico have identified the presence of bacteria in the healthy brains of fish. Understanding this connection between bacteria and animal brains could have future implications for the study of Alzheimer's disease......»»
Brazilian study identifies potential targets for treatment of visceral leishmaniasis
Researchers at the Federal University of São Carlos (UFSCar), the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil have characterized for the first time a class of proteins present in the parasite Leishmania in.....»»
Glowing proteins enable real-time, 3-D study of essential enzymes
Working in organoid models, researchers at University of California San Diego School of Medicine have developed a new tool to study protein-kinase C (PKC) enzymes, which play a critical role in cell growth, differentiation and survival. Malfunction o.....»»
Calcium transport protein in bacteria offers insights for drug development and food safety
Researchers at Umeå University have revealed details on how bacteria use calcium to regulate vital processes in a way that differs from human cells. This breakthrough is significant in the fight against antibiotic resistance and for increasing safet.....»»
I was a beta tester for the Nobel prize-winning AlphaFold AI—it"s going to revolutionize health research
The deep learning machine AlphaFold, which was created by Google's AI research lab DeepMind, is already transforming our understanding of the molecular biology that underpins health and disease......»»
Protein USP50 identified as key in DNA replication balance
A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study......»»
Expansion in situ genome sequencing innovation makes hidden DNA-protein interactions visible
Harvard scientists have unveiled a new technique called expansion in situ genome sequencing (ExIGS) that combines existing in situ genome sequencing (IGS) with expansion microscopy (ExM). The innovation allowed researchers to link nucleus abnormaliti.....»»
New insights into grain boundary kinetics challenge traditional views
Researchers from City University of Hong Kong (CityUHK), in collaboration with experts from local and overseas universities, have reshaped scientists' fundamental understanding of the kinetic processes in crystalline materials, throwing light on new.....»»
Machine learning cracked the protein-folding problem and won the 2024 Nobel Prize in chemistry
The 2024 Nobel Prize in chemistry recognized Demis Hassabis, John Jumper and David Baker for using machine learning to tackle one of biology's biggest challenges: predicting the 3D shape of proteins and designing them from scratch......»»
Targeting "undruggable" diseases: Researchers reveal new levels of detail in targeted protein degradation
Researchers at the University of Dundee have revealed in the greatest detail yet the workings of molecules called protein degraders which can be deployed to combat what have previously been regarded as "undruggable" diseases, including cancers and ne.....»»
Study proposes that proteins can compartmentalize and form droplets inside cells
In physics, a system composed of two substances can be modeled in accordance with classical mixture theory, which considers the fraction corresponding to each constituent and the interactions among constituents. Examples include the coexistence of hi.....»»
Event horizon: After photographing black holes, scientists are now making a movie
The first moving images of a black hole could reveal swirls of plasma and collapsing stars, deepening our understanding of the universe......»»