Picky proteins: Understanding yeast adaptor protein selectivity
The cellular membrane controls the passage of substances in and out of the cell. Some larger cargo, such as membrane proteins, nutrients, and pathogens, enter the cell via a process known as clathrin-mediated endocytosis......»»
Study shows an electrically-activated protein regulates spermatogenesis
Frankenstein's monster was brought to life by the judicious application of a little electricity; and a surprising number of processes in our bodies are regulated by electrical currents too. Now, researchers from Japan reveal that electricity may play.....»»
Supercomputer simulations reveal the nature of turbulence in black hole accretion disks
Researchers at Tohoku University and Utsunomiya University have made a breakthrough in understanding the complex nature of turbulence in structures called accretion disks surrounding black holes, using state-of-the-art supercomputers to conduct the h.....»»
Study finds flexibility and helical twists of actin filaments regulate actin-binding proteins
Researchers at Kanazawa University have published an article in eLife deciphering the actin structure-dependent preferential cooperative binding of cofilin......»»
Chloroplast manipulation: A new strategy in pathogen warfare uncovered
A recent study has unveiled the sophisticated methods pathogens use to weaken plant defenses. It shows how a pathogen's effector protein targets the chloroplast protein StFC-II, increasing its levels in chloroplasts and reducing the plant's ability t.....»»
Uncertainty is a key factor in the relationship between work injury and mental health, research shows
Mental health and workplace injuries are known to be closely linked, but there are significant gaps in our deeper understanding of that bidirectional relationship. How does one affect the other, what moderates the relationship and what are the long-t.....»»
Simulation model shows ribosome tunnel"s impact on protein structures
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»
Cold math, hot topic: Applied theory offers new insights into sea ice thermal conductivity
A new applied mathematical theory could enhance our understanding of how sea ice affects global climate, potentially improving the accuracy of climate predictions......»»
Population genetic insights into the conservation of common walnut (Juglans regia) in Central Asia
Understanding species distribution, differentiation and the factors affecting genetic diversity is important for sustainable conservation and effective management, as well as the rational utilization of species germplasm......»»
Toyota, BMW to upgrade fuel cell alliance, report says
BMW and Toyota plan to sign a memorandum of understanding for the partnership next week, with an official announcement set for Sept. 5, Nikkei Asia reported......»»
Half of enterprises suffer breaches despite heavy security investments
Data breaches have become an increasingly severe threat, with recent reports highlighting a surge in their frequency and cost. Understanding the latest trends and statistics surrounding data breaches is essential for developing effective strategies t.....»»
Dual protein analysis approach provides potential way to slow cancer growth
Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays a critical role in this process by helping researchers identify protei.....»»
Scientists use evolution to bioengineer new pathways to sustainable energy and pharmaceuticals
Using evolution as a guiding principle, researchers have successfully engineered bacteria-yeast hybrids to perform photosynthetic carbon assimilation, generate cellular energy and support yeast growth without traditional carbon feedstocks like glucos.....»»
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
Discovery of a hidden epigenetic clock in mitochondria reveals a "lifespan limit line"
Building on their work on epigenetics of aging and transposable elements, researchers Dr. Ádám Sturm and Dr. Tibor Vellai from Eötvös Loránd University have made another advance in understanding the molecular mechanisms of aging. Their latest st.....»»
3D shapes of viral proteins point to previously unknown roles
Viruses are tricky to keep up with. They evolve quickly and regularly develop new proteins that help them infect their hosts. These rapid shifts mean that researchers are still trying to understand a multitude of viral proteins and precisely how they.....»»
Tomato ripening study highlights cell wall component interactions
Tomato fruit ripening involves intricate biochemical and structural changes, particularly within the cell wall, which are vital for the fruit's final texture and quality. These changes include modifications in polysaccharides and proteins, but the sp.....»»
Unlocking crop yield potential: New modeling approach for sustainable agriculture
Predicting crop yields is a significant challenge in modern agriculture, especially under fluctuating environmental conditions. With the escalating demand for sustainable food production, understanding the complex interplay between environmental fact.....»»
Yeast meiosis study finds temperature changes result in shorter meiotic chromosome axes and more crossovers
In a study of meiosis in budding yeast, a research team found that yeast senses temperature changes by increasing the level of DNA negative supercoils to increase crossovers and modulate chromosome organization during meiosis......»»
Extreme rainfall event study demonstrates improved forecasting via physics-guided machine learning
A research team focused on the extreme rainfall event of "21·7" in Henan in 2021. By analyzing anomalous physical characteristics and understanding multi-model forecast biases, they significantly enhanced the accuracy of precipitation intensity fore.....»»
Addressing the environmental impact of hematology care
An In-Focus analysis in The Lancet Hematology calls for greater understanding of greenhouse gas (GHG) emissions, to inform effective and prudent health practice in hematology care......»»