New drug target for Ebola, Marburg viruses
Researchers have identified a previously unknown site on the filovirus glycoprotein to which small drug molecules can bind and prevent infection -- blocking both sites may be a more effective treatment while reducing the risk of side effects......»»
Gene silencing tool has a need for speed: Research provides deeper insight into RNAi tool design
RNA interference (RNAi) is a process that many organisms, including humans, use to decrease the activity of target RNAs in cells by triggering their degradation or slicing them in half. If the target is a messenger RNA, the intermediary between gene.....»»
The Lucid Air Pure review: Lower weight, better steering, amazing efficiency
Less power and less weight almost always makes for a better electric vehicle. Enlarge / At just under $70,000, the Lucid Air Pure is closer to the company's original target for an entry-level model than the "under $80,000" it tol.....»»
Study shows ancient viruses fuel modern-day cancers
Peek inside the human genome and, among the 20,000 or so genes that serve as building blocks of life, you'll also find flecks of DNA left behind by viruses that infected primate ancestors tens of millions of years ago......»»
Influenza viruses can use a second entry pathway to infect cells, study shows
Most influenza viruses enter human or animal cells through specific pathways on the cells' surface. Researchers at the University of Zurich have now discovered that certain human flu viruses and avian flu viruses can also use a second entry pathway,.....»»
Engineered nanovesicles from activated neutrophils show promise in treating infected wounds
Infectious wounds represent a critical challenge in health care, especially for diabetic patients grappling with ineffective antibiotics and escalating drug resistance. Conventional therapies often inadequately address deep tissue infections, highlig.....»»
The evolving single-cell and spatial technology landscape
The scTrends consortium has published its first report shedding light on the current state of the commercial single-cell and spatial genomics industry and its potential impact on drug discovery and patient care......»»
Chemists develop modular approach for creating important class of pharmaceutical compounds
Chemists at the National University of Singapore (NUS) have developed a modular approach to create 1,2-arylheteroaryl ethanes, a class of compounds important for drug discovery and pharmaceutical development, using fundamental feedstock chemicals suc.....»»
Best Target Prime Day deals: Circle Week deals still available
With the discounts that you can get from these Target Prime Day deals, you'll be able to buy a TV or other appliance for your home for much cheaper than usual......»»
Rite Aid says breach exposes sensitive details of 2.2 million customers
Stolen data includes customer names, addresses, birth dates, and driver's license numbers. Enlarge / Rite Aid logo displayed at one of its stores. (credit: Getty Images) Rite Aid, the third biggest US drug store chain, s.....»»
Study shows frogs can quickly increase their tolerance to pesticides
Although there is a large body of research on pests evolving tolerances for the pesticides meant to destroy them, there have been considerably fewer studies on how non-target animals in these ecosystems may do the same......»»
Researchers develop library for RNA-based therapeutic approaches with polymer nanoparticles
RNA therapy with polymer nanoparticles is considered a promising approach for the treatment of various illnesses. It involves the use of polymers as "nanocarriers" to transport RNA drugs precisely to the correct target cells. Manufacturing such polym.....»»
Lab develops smallest free-floating bubbles for medical imaging
Bioengineering researchers at Rice University have developed ultrasmall, stable gas-filled protein nanostructures that could revolutionize ultrasound imaging and drug delivery......»»
New class of organic nanoparticles shows promise for diverse applications
Nanoparticles have a wide variety of applications, from drug delivery to electronics to air purification. Their small size and tunable properties make them particularly valuable for technological advancements and scientific research. When polymers ma.....»»
Car thieves target Michigan dealerships; police say it"s an organized theft ring
Dealers are being advised by Michigan State Police to keep their keys in a safe and increase security measures to mitigate the impact......»»
Research team develops light-activated compounds to treat neuropathic pain
Light can be used to activate drugs in specific parts of the body through photopharmacology. This innovative approach involves modifying the chemical structure of a drug by adding a light-activated molecular switch, such as azobenzene. This allows th.....»»
Understanding the role of RNA methylation in cancer
RNA modification could serve as a therapeutic target for certain types of cancer, according to a new study published in Molecular Cell, which sheds new light on the complex process underlying RNA transcription......»»
A comprehensive derivative synthesis method for development of new antimicrobial drugs
Efforts to combat the increasing threat of drug-resistant bacteria are being assisted by a new approach for streamlining the search for antimicrobial drug candidates, pioneered by researchers at Hokkaido University, led by Assistant Professor Kazuki.....»»
Thieves target Hollywood Hills home in multi-million dollar heist
Thieves target Hollywood Hills home in multi-million dollar heist.....»»
Study: Nanoparticle vaccines enhance cross-protection against influenza viruses
To offer cross-protection against diverse influenza virus variants, nanoparticle vaccines can produce pivotal cellular and mucosal immune responses that enhance vaccine efficacy and broaden protection, according to a study by researchers in the Insti.....»»
What Makes a Psychedelic Experience? Not Always a Drug, It Turns Out
A Stanford anesthesiologist deconstructs the component parts of what it means to undergo a psychedelic trip.....»»