New drug target for Ebola, Marburg viruses
Researchers have identified a previously unknown site on the filovirus glycoprotein to which small drug molecules can bind and prevent infection -- blocking both sites may be a more effective treatment while reducing the risk of side effects......»»
Electrical impedance tomography plus extracellular voltage activation technique simplifies drug screening
When developing new drugs, understanding their effects on ion channels in the body, such as the human ether-a-go-go-related gene (hERG) ion channel found in neurons and heart muscle cells, is critical. Blocking hERG channels can disrupt a normal hear.....»»
DART mission sheds new light on target binary asteroid system
In studying data collected from NASA's DART (Double Asteroid Redirection Test) mission, which in 2022 sent a spacecraft to intentionally collide with the asteroid moonlet Dimorphos, the mission's science team has discovered new information on the ori.....»»
A new model to study regeneration of brown adipose tissues
The prevalence of obesity worldwide has led to an increase in the risk of metabolic diseases and socio-economical burdens. Brown adipose tissue (BAT) has been established as a promising therapeutic target to overcome obesity, type 2 diabetes (T2D) an.....»»
Developing new methods for targeted protein degradation
Northwestern Medicine scientists have developed a new, more precise method to target proteins implicated in certain types of cancer, according to a study published in Nature Chemical Biology......»»
"Russian doll" packaging could boost drug delivery
New technology, which is in the early stages of development, has the potential to significantly enhance the effectiveness and reduce the side effects of drugs and vaccines......»»
TD Cowen raises AAPL target to $250 on AI and China sales
Investment analyst firm TD Cowen predicts that Apple Intelligence will bring a modest boost to the iPhone 16 range, but be much more significant in 2025, by when China sales are expected to have returned to growth.Render of the iPhone 16 rangeAhead o.....»»
New and improved drug-delivery molecules for skeletal muscle
Researchers from Tokyo Metropolitan University have created a new drug-delivery molecule, a zwitterionic polymer complex that can help get plasmid DNA inside cells when injected into skeletal muscle, a crucial step in the expression of therapeutic RN.....»»
Apple, Amazon target Twitch users for new Apple TV+ trial promotion
Apple and Amazon have teamed up to offer a new three-month free trial of Apple TV+ to Twitch users who subscribe to any Twitch streamer.Popular series featured on Apple TV+ in new promotional campaign with Twitch.Users can subscribe to a Twitch strea.....»»
France’s cyber unit preps for cyberattacks targeting Paris Olympics
Paris Olympics organizers are expecting a wave of cyberattacks to target the Games when the sporting extravaganza kicks off in earnest this weekend......»»
Kia Tasman pickup unlikely to be available in the U.S.
The automaker released video of the off-road capable truck simulating testing in California, but its target markets are overseas......»»
Volvo softens EV-or-bust strategy as hybrids show promise
Some Volvo dealers fear the consequences of sticking to the 2030 target as EV growth slows, and CEO Jim Rowan says hybrids can be a bridge for customers not ready to dump gasoline......»»
Scientists hijack natural delivery system to send engineered proteins to target cells
Each cell in the body has its own unique delivery system that scientists are working on harnessing to move revolutionary biological drugs—molecules like proteins, RNA and combinations of the two—to specific diseased parts of the body......»»
Research team develops new antimalarial agent for combating drug-resistant parasites
Malaria remains a serious health issue globally, especially in Africa. The disease is caused by protozoan parasites in the Plasmodium genus. In 2021, there were 247 million cases of malaria and 619,000 deaths reported worldwide......»»
Counter-drug strategies in Central America are worsening deforestation, threatening many species of birds
Activities associated with cocaine trafficking threaten two-thirds of the most important landscapes in Central America for 196 forest bird species, including 67 migratory species. This is the key takeaway from a study that colleagues and I published.....»»
Lethal bird flu could decimate Oceania"s birds—from vigilance to vaccines, here"s what Australia is doing to prepare
Avian influenza viruses have infected the world's birds for millennia. We first became aware of them in the 19th century, when mass deaths of poultry triggered interest in what was then called "fowl plague.".....»»
Security Bite: North Korean hackers impersonate job recruiters to target Mac users with updated BeaverTail malware
9to5Mac Security Bite is exclusively brought to you by Mosyle, the only Apple Unified Platform. Making Apple devices work-ready and enterprise-safe is all we do. Our unique integrated approach to management and security combines state-of-the-art App.....»»
Illegal drug found in Diamond Shruumz candies linked to severe illnesses
New testing finds psilocin, related to psilocybin, in gummies purchased in 2023. Enlarge (credit: Diamond Shruumz) Newly released testing data of Diamond Shruumz-brand gummies purchased in 2023 identified the presence of.....»»
De-risking drug discovery with predictive AI
Developing a new drug can take years of research and cost millions of dollars. Still, more than 90% of drug candidates fail in clinical trials, with even more that never make it to the clinical stage. Many drugs fail because they simply aren't safe......»»
Dynamic view of opioid receptor could refine pain relief
Effective pain relief without the debilitating side effects of traditional opioids is closer to becoming a reality thanks to a study by an all-RIKEN team into the structure and dynamics of a drug-bound opioid receptor......»»
New model explains precise timing of viral cell bursting
New research from Rice University scientists is shedding light on how viruses ensure their survival by precisely timing the release of new viruses. The discovery offers a new theoretical framework for understanding these dynamic biological phenomena......»»