New drug target for Ebola, Marburg viruses
Researchers have identified a previously unknown site on the filovirus glycoprotein to which small drug molecules can bind and prevent infection -- blocking both sites may be a more effective treatment while reducing the risk of side effects......»»
What Makes a Psychedelic Experience? Not Always a Drug, It Turns Out
A Stanford anesthesiologist deconstructs the component parts of what it means to undergo a psychedelic trip.....»»
A Combination COVID and Flu Vaccine Is Coming Soon
The first large trial of a COVID and flu vaccine combo suggests it boosts immune protection even more than single-target shots.....»»
We’re Not Asking the Right Question to Solve the Overdose Crisis
Drug policy continues to fixate on symptoms rather than the actual disease.....»»
Google considered blocking Safari users from accessing its new AI features, report says
Google’s dominance of the search industry is the target of an ongoing Justice Department investigation – and its relationship with Apple is a key component of that case. A new report from The Information today focuses on how Google is racing to.....»»
Drug middlemen inflate US prices, squeeze out competition, FTC says
Pharmacy benefit managers (PBMs) are key part of US's high drug costs, report finds. Enlarge / Lina Khan, chair of the Federal Trade Commission (FTC), testifies before the House Appropriations Subcommittee at the Rayburn House O.....»»
Receptors make dairy cows a prime target for influenza, team finds
As highly pathogenic avian influenza has spread in dairy herds across the U.S., the virus is being detected in raw milk. A new study by a broad team of researchers at Iowa State University's College of Veterinary Medicine helps explain why......»»
New weight-loss and diabetes drugs linked to lower risk of 10 cancers
For diabetes patients, GLP-1 drugs linked to lower cancer risks compared to insulin. Enlarge / Ozempic is a GLP-1 drug for adults with type 2 diabetes. (credit: Getty | Steve Christo) For patients with Type 2 diabetes, t.....»»
"Sacrifice" of virus data clears the path to open a disease discovery pipeline
Tens of millions of still-unknown or misunderstood viruses can cause diseases—including new pandemics—and affect the health of valuable terrestrial and marine environments......»»
Piper Sandler raises Apple target price on promise of AI
Investment firm Piper Sandler says the market is right to be excited by Apple Intelligence, and also that it sees a return to iPhone growth in the key market of China.Renders of a possible designs for the iPhone 16 rangeBased on both AI and China, We.....»»
Elon Musk shares target date for fifth test of Starship megarocket
SpaceX chief Elon Musk has said when he thinks the mighty Starship rocket will be ready to take its fifth test flight......»»
First set of rational design principles for chaotropic membrane transporters
The challenge of internalizing impermeable molecules into cells persists in drug development, particularly concerning water-soluble bioactive compounds that cannot diffuse across the cell membrane. To overcome this problem, various artificial transpo.....»»
Features of H5N1 influenza viruses in dairy cows may facilitate infection, transmission in mammals
A series of experiments with highly pathogenic H5N1 avian influenza (HPAI H5N1) viruses circulating in infected U.S. dairy cattle found that viruses derived from lactating dairy cattle induced severe disease in mice and ferrets when administered via.....»»
Scientists discover new way to control blood vessel growth with the peptide Apelin
Scientists from La Trobe University and Phillipps-University of Marburg (Germany) have discovered how a peptide called Apelin regulates blood vessel growth, opening new avenues of research for cancer treatment, organ regeneration, and tissue engineer.....»»
AI able to identify drug-resistant typhoid-like infection from microscopy images in matter of hours
Artificial intelligence (AI) could be used to identify drug resistant infections, significantly reducing the time it takes for a correct diagnosis, Cambridge researchers have shown. The team determined that an algorithm could be trained to identify d.....»»
Mississippi lacks Black doctors, even as lawmakers increasingly target diversity programs
Medical schools around the country are trying to recruit Black, Hispanic, and Native American students, all of whom remain disproportionately underrepresented in the field of medicine. Research has shown that patients of color prefer seeing doctors o.....»»
AI approach optimizes development of antibody drugs
Proteins have evolved to excel at everything from contracting muscles to digesting food to recognizing viruses. To engineer better proteins, including antibodies, scientists often iteratively mutate the amino acids—the units that are arranged in a.....»»
Phage viruses, used to treat antibiotic resistance, gain advantage by cutting off competitors" reproduction ability
Curious bits of DNA tucked inside genomes across all kingdoms of life historically have been disregarded since they don't seem to have a role to play in the competition for survival, or so researchers thought......»»
SpaceX reveals target date for a crewed mission like no other
SpaceX has revealed a target date for its highly anticipated Polaris Dawn mission, which will see four civilians fly a Crew Dragon to its highest-ever altitude......»»
How studying bat viruses can help prevent zoonotic disease
Bats have become the poster child of emerging zoonotic disease. The creatures harbor a vast array of viruses—some of which cause deadly diseases in humans—yet they rarely get sick themselves......»»
Exploring the molecular basis of how pradimicin A binds to viral N-glycan, a potential SARS-CoV-2 entry inhibitor
HIV, Ebola and most recently, COVID-19 viruses have had an enormous impact on our societies world-wide. All these viruses are "enveloped viruses," viruses that have an exterior envelope that surrounds them largely composed of their host's cells. This.....»»