New drug inhibits the growth of cancer cells
A newly developed compound starves cancer cells by attacking their "power plants"—the so-called mitochondria. The new compound prevents the genetic information within mitochondria from being read. Researchers from the Max Planck Institute for Biolo.....»»
"Inside-out" galaxy growth observed in the early universe
Astronomers have used the NASA/ESA James Webb Space Telescope (JWST) to observe the 'inside-out' growth of a galaxy in the early universe, only 700 million years after the Big Bang......»»
Claustrophobic cells slow their own growth, forming beautiful patterns of concentric circles
Like so many organisms on the planet, when cells experience mosh-pit-level crowding, they may just become stressed. Yet unlike most other life forms, cells subject to physical stress from crowding by neighbors can find some relief by dramatically slo.....»»
Advanced model predicts gene architecture via nucleosome position
DNA—the molecule that carries the genetic information of all living organisms—is packaged within cells in a complex manner that allows it to function efficiently. Nucleosomes facilitate DNA compaction and also play a crucial role in regulating ge.....»»
Mac sales are nosediving
Macs have reportedly experienced a 17.5% drop in annual growth in this past quarter......»»
From chaos to structure: How a bunch of seemingly disorganized cells go on to form a robust embryo
Pipetting liquids into tiny test tubes, analyzing huge datasets, poring over research publications—all these tasks are part of being a scientist. But breaking this routine is essential. Time away from the usual work environment can spark creative i.....»»
watchTowr raises $19 million to accelerate global growth
watchTowr announced a $19 million Series A funding round led by Peak XV, formerly known as Sequoia India & Southeast Asia, with repeat participation from Prosus Ventures and Cercano Management. The company will use the funds to capture market leaders.....»»
Recall platform BizzyCar raises $15 million led by Dealer Tire
BizzyCar, a technology platform that automates recalls, closed a $15 million growth funding round led by Dealer Tire......»»
Drug makers can’t make knockoff weight-loss drugs anymore—and they’re mad
Compounding pharmacies could make knockoffs during shortage. But FDA says it's over. Compounding pharmacies are suing the Food and Drug Administration so they can keep making imit.....»»
Making micelles more effective for dye and drug dispersion through well-defined core-shell structures
Micelles are spherical molecular structures usually formed by amphiphilic molecules with block structure, which contain both hydrophilic and hydrophobic parts. The hydrophobic tails of these molecules cluster together to form a core, while the hydrop.....»»
Industry sees influx of qualified minority dealer candidates, NAMAD president says
Automakers see the most success with minority dealer growth when it's a business directive that comes from the top of the company, said NAMAD President Perry Watson IV......»»
How Chlamydia pneumoniae bacteria use molecular mimicry to manipulate the host cell
Bacteria that cause diseases, so-called pathogens, develop various strategies to exploit human cells as hosts to their own advantage. A team of biologists from Heinrich Heine University Düsseldorf (HHU), together with medical professionals and exper.....»»
A Major GLP-1 Drug Shortage Is Over. Some Patients Aren’t Celebrating
Mounjaro and Zepbound are now out of shortage. This should be good news—but because so many patients are taking compounded versions of these GLP-1 medications, it’s a complicated situation......»»
Cryo-electron microscopy provides new insights into the cell"s repair system
The membrane that surrounds cells in living organisms is extremely flexible and sensitive. How it protects itself from damage and renews itself is crucial for many life processes, and is not yet fully understood in detail. Scientists at Forschungszen.....»»
Researchers design a drug capable of acting simultaneously against three different therapeutic targets
A study led by researchers of the Institute of Biomedicine of the University of Barcelona (IBUB) has developed a new pharmacological tool capable of simultaneously administering three oligonucleotide-based drugs, each acting against a different thera.....»»
Nanopore technique shows transport mechanism of chaperone proteins at the single-molecule level
Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control protein quality......»»
Research team develops metallodrug-antibiotic combination strategy to combat superbugs
Antimicrobial resistance (AMR) bacterial infections have become a serious problem threatening human health worldwide. The overuse of antibiotics has promoted drug-resistant mutations in bacteria, causing almost all clinically used antibiotics to deve.....»»
Single-celled eukaryote employs unconventional cytoskeletal components for dynamic shape-shifting
Recently, a research group led by Prof. Miao Wei from the Institute of Hydrobiology (IHB) of the Chinese Academy of Sciences discovered that Lacrymaria cells utilize unconventional and novel components of the cytoskeleton to achieve their remarkable.....»»
Alcohol Plays a Major Role in New Cancer Cases
A new report estimates that 40 percent of all cancer cases are associated with factors we can change—alcohol consumption being a prominent one......»»
AI and quantum mechanics team up to accelerate drug discovery
Drug discovery is much like working a jigsaw puzzle. The chemical compounds behind drug molecules must be shaped to fit with the proteins in our bodies to produce therapeutic effects. That requirement for a meticulous fit means the creation of new dr.....»»
SCOTUS denial ends saga of Shkreli’s infamous 5,000% drug price scheme
The Supreme Court offered no explanation for denying the petition. The legal saga over Martin Shkreli's infamous 5,000 percent price hike of a life-saving anti-parasitic drug has.....»»