New "decision aid" for CRISPR immune responses
Friend or foe? Immune systems constantly face this question. They must recognize and clear foreign invaders without eliciting autoimmunity. Prokaryotic CRISPR-Cas systems recognize invaders based on genetic sequence. But what happens if the host geno.....»»
Breaking boundaries: PAM-less genome editing in soybean
CRISPR-Cas9 has transformed crop genetic improvement, yet its reliance on specific protospacer adjacent motif (PAM), sequences limits editing scope and efficiency. In soybean, a critical source of protein and oil, these limitations hinder the develop.....»»
3D bioprinting materials offer possibility for better bone and soft tissue repair
3D bioprinting is an advanced tissue engineering technique that builds complex tissues using bioactive substances like living cells and scaffolds. It provides personalized tissue repair solutions, reducing immune rejection by using patient-specific c.....»»
Fed"s decision could benefit industry, but how about customers?
Our editorial board weighs in on the possibility of interest rate cuts......»»
NASA makes a very tough decision in setting final Crew-9 assignments
"I am deeply proud of our entire crew." Enlarge / Nick Hague, left, and Zena Cardman train inside a Crew Dragon spacecraft mock-up in November 2023. (credit: NASA) On Friday NASA publicly announced a decision that has r.....»»
California legislature passes controversial “kill switch” AI safety bill
Governor will balance worries about "over-regulation" with calls from AI luminaries. Enlarge / California governor Gavin Newsom will likely soon face a decision on whether to sign SB-1047. (credit: Ray Chavez/The Mercury News via.....»»
Arctic heat waves linked to sea ice loss, new study reveals
Amid global warming, heat waves are striking even the Arctic, a region once considered immune to such extreme weather events. Recent research reveals that these heat waves, particularly in the Barents-Kara Sea (BKS) during the boreal autumn, are not.....»»
Using metal ion-linked nanostructures to improve immune response and boost breast tumor treatment
Immune checkpoint blockade (ICB) is one of the primary methods of tumor immunotherapy. However, clinical data have shown that only a portion of patients respond to ICB treatment. Since the tumor's immune-suppressive environment plays a crucial role i.....»»
Should misogyny be treated as a form of extremism?
The UK government has recently announced a review into their counter-terrorism strategy, focusing on responses to "extremist ideologies." This announcement named misogyny as one of its extremist ideological trends of interest......»»
While some cities clear homeless encampments, others are granting a "right to shelter"
At the end of June, the US Supreme Court upheld an Oregon city's ban on outdoor camping. The court's decision means that people experiencing homelessness can be arrested, ticketed and fined for sleeping outside, even when there are no alternatives......»»
The best Syndicate rewards in Star Wars Outlaws
Picking which criminal syndicate you want to align yourself with in Star Wars Outlaws is a big decision. Here's what you get for maxing out your reputation......»»
New technique paves the way for efficient vitamin D3 production
Scientists have developed a method to produce vitamin D3 (VD3), a vital nutrient for bone health and immune function, with greater efficiency and purity. This breakthrough utilizes intricately designed microchannels carved into glass using ultra-fast.....»»
Study identifies keys to success of evidence-based decision making
Evidence-based decision making (EBDM)—using the best available evidence from multiple sources to make informed decisions—is critical to the success of any organization. In a new study, researchers have explored what makes EBDM work. They found th.....»»
A hybrid arrowhead against immune disorders: Bacterially derived natural product inhibits cellular immune response
The so-called immunoproteasome is essential for the cellular immune response. In autoimmune diseases, however, it is overactive. Until now, it has not been possible to selectively inhibit the immunoproteasome without disrupting other cellular mechani.....»»
The Boeing Starliner Astronauts Will Come Home on SpaceX’s Dragon Next Year
The decision will leave the crew on the ISS until February. The mission was initially supposed to last about a week......»»
NASA’s Starliner decision was the right one, but it’s a crushing blow for Boeing
It's unlikely Boeing can fly all six of its Starliner missions before retirement of the ISS in 2030. Enlarge / A Starliner spacecraft mounted on top of an Atlas V rocket before an unpiloted test flight in 2022. (credit: Boeing).....»»
The Boeing Starliner Astronauts Will Come Home on SpaceX"s Dragon Next Year
The decision will leave the crew on the ISS until February. The mission was initially supposed to last about a week......»»
NASA to announce decision about stuck Starliner astronauts tomorrow
It's now been more than two months since the Boeing Starliner launched on what was supposed to be a one-week mission. NASA will provide an update tomorrow......»»
Could 2 NASA astronauts be stuck at the space station until next year? A decision is imminent
Will two NASA astronauts return to Earth soon in their troubled Boeing capsule? Or wait at the International Space Station for a ride home next year with SpaceX?.....»»
Researchers achieve first CRISPR-based genome editing in Nile grass rats
A team of researchers at Michigan State University has discovered a set of methods that enabled the first successful CRISPR-based genome editing in Nile grass rats......»»
Cards on the table: Are Butch and Suni coming home on Starliner or Crew Dragon?
On the eve of a fateful decision, we're answering some frequently asked questions. Enlarge / NASA astronauts Suni Williams and Butch Wilmore, seen in their Boeing flight suits. (credit: NASA/Francisco Martin) After month.....»»