Moonlighting protein makes a hospital germ harmful
The Pseudomonas aeruginosa bacterium is a widespread and dangerous hospital germ. It infects the respiratory tract and lungs and possesses natural resistance to numerous antibiotics. There is an ongoing search for so-called pathoblockers to be able t.....»»
Scientists" new drug-delivery technology is possible breakthrough for multi-strain vaccines
A new way to deliver drugs using a common protein could be used to develop mosaic vaccines, which are vaccines effective against multiple strains of a virus like COVID-19, among other medicines in a global first......»»
Comparison of four methods on drying efficiency and physicochemical properties of chicken meat
Chicken breast jerky (CBJ) is a popular pet food due to its high crude protein content and long shelf life. In the production of CBJ, the drying process is a crucial step. However, the physicochemical and functional properties of CBJ depend on the dr.....»»
By listening, scientists learn how a protein folds
By converting their data into sounds, scientists discovered how hydrogen bonds contribute to the lightning-fast gyrations that transform a string of amino acids into a functional, folded protein......»»
Scientists introduce DIProT—an interactive deep learning toolkit for efficient protein design
Scientists have developed DIProT, an innovative, user-friendly toolkit for protein design. The toolkit utilizes a non-autoregressive deep generative model to address the protein inverse folding problem, integrating human expertise into the design loo.....»»
Using hybrid nanotubes to enhance cancer treatment with intracellular protein delivery
The intracellular delivery of proteins is an important technique for unveiling the cellular functions, protein complex structure, and therapeutics. However, conventional delivery methods have several limitations......»»
Study reveals how a sugar-sensing protein acts as a "machine" to switch plant growth—and oil production—on and off
Proteins are molecular machines, with flexible pieces and moving parts. Understanding how these parts move helps scientists unravel the function a protein plays in living things—and potentially how to change its effects. Biochemists at the U.S. Dep.....»»
Protein prediction technology yields accurate results to efficiently find the best drug candidate for many conditions
Artificial intelligence (AI) has numerous applications in health care, from analyzing medical imaging to optimizing the execution of clinical trials, and even facilitating drug discovery......»»
The First Person to Receive a Pig Kidney Transplant Has Died
The hospital that carried out the procedure two months prior says there’s “no indication” that the transplant was related to his death......»»
Study reveals insights into protein evolution
Rice University's Peter Wolynes and his research team have unveiled a breakthrough in understanding how specific genetic sequences, known as pseudogenes, evolve. Their paper was published May 13 in the Proceedings of the National Academy of Sciences......»»
Nitrogen pollution is less harmful to mixed forests, study shows
In a study published in the journal Plant and Soil, researchers from the Institute of Applied Ecology of the Chinese Academy of Sciences have shown that mixed larch and deciduous forests are more resistant to soil acidification—a decrease in soil p.....»»
Protein assembly research shows molecular roll of the dice delivers winning combinations
Australian researchers have shed light on the shape-shifting capabilities of protein assemblies, with results that could revolutionize fields from biomanufacturing to vaccine development......»»
Research holds promise for liver regeneration
A new study titled "Biomimetic hepatic lobules from three-dimensional imprinted cell sheets" has been led by Prof. Yuanjin Zhao of the Department of Hepatobiliary Surgery, Hepatobiliary Institute, Nanjing Drum Tower Hospital, Medical School, of Nanji.....»»
Genes spatially organize for efficient mRNA splicing, study shows
The nucleus of each of your cells contains all the genetic information (the genome) necessary to build every type of cell and protein in your entire body. Like a complex library in a tiny space 50 times smaller than the width of a human hair, genes a.....»»
DeepMind adds a diffusion engine to latest protein-folding software
Major under-the-hood changes let AlphaFold handle protein-DNA complexes and more. Enlarge / Prediction of the structure of a coronavirus Spike protein from a virus that causes the common cold. (credit: Google DeepMind) M.....»»
MATE transporter facilitates bitter saponin transport from cytoplasm to vacuole
Domestic soybeans serve as an important source of healthy edible plant oil and high-quality plant protein in our food culture. In addition to the well-known components of oil (approximately 20%), protein (approximately 40%), and carbohydrates (approx.....»»
AI simulation of flavored vape reactions reveals formation of many hazardous chemicals
New research has uncovered the potentially harmful substances that are produced when e-liquids in vaping devices are heated for inhalation. The study, published in Scientific Reports, highlights the urgent need for public health policies concerning f.....»»
Loss of large herbivores affects interactions between plants and their natural enemies, study shows
Insects and microorganisms that feed on plants, cut up leaves, modify leaf tissue or produce leaf spots and other kinds of damage, are usually known as pests and considered harmful, yet interactions between plants and their natural enemies are import.....»»
Scientists use high pressure NMR spectroscopy to study structure of dynamic proteins
A pressure of 3,000 bar is applied to the cold shock protein B of Bacillus subtilis in a small tube in the NMR spectroscopy laboratory at the University of Konstanz. This is roughly three times the water pressure at the deepest point of the ocean. Th.....»»
Synthetic chemistry approach yields new compounds with potential biomedical applications
Researchers at Rice University have successfully synthesized a group of natural compounds known as fusicoccanes. The molecules found in various living organisms exhibit diverse biological activities, including the ability to modulate protein-protein.....»»
New discovery of a mechanism that controls cell division
Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of.....»»