Molecular gardening: New enzymes discovered for protein modification pruning
Deubiquitinases (DUBs) are enzymes used by cells to trim protein modifications made from the protein ubiquitin, and thereby regulate proteins. Malfunctioning of DUBs could lead to diseases, including cancer and neurodegenerative disorders......»»
Protein signaling pathway provides insights into cell migration and cancer metastasis
The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a village: a combination of physical barriers, chemical attacks, and an army of specialized white blood cells. But maintaining and.....»»
Abiotic organic synthesis research proposes new mechanism for organic condensation
A Chinese research team has reported the discovery of abiotic organic compounds in the oceanic crust of the Southwest Indian Ridge and proposed a molecular mechanism for organic condensation......»»
Cryo-electron microscopy sheds light on endothelin signaling mechanisms
Endothelin is a peptide hormone known for its vasoconstrictive effects. Researchers at University of Tsukuba used cryo-electron microscopy to examine the complex structure of the endothelin receptor and G protein, which are crucial for signal transdu.....»»
Scientists Peeked Underneath the Seafloor and Discovered Something "Totally Unexpected"
Scientists Peeked Underneath the Seafloor and Discovered Something "Totally Unexpected".....»»
"Old" star could provide new insights into star evolution
A newly discovered star could challenge some models of how stars evolve and the way they produce elements as they age......»»
MicroRNA, Protein Folding and Machine-Learning Work Win the Science Nobels
A roundup of the science Nobels, the latest COVID updates and the Europa Clipper launch delay......»»
A look at the oldest stone tools ever discovered, dating back 3.3M years
A look at the oldest stone tools ever discovered, dating back 3.3M years.....»»
Atlanta millionaire discovered her husband lied on their prenup and stole roughly $386K. Ramsey Show hosts are shocked
Atlanta millionaire discovered her husband lied on their prenup and stole roughly $386K. Ramsey Show hosts are shocked.....»»
iOS 18.1 brings a surprise Apple Intelligence upgrade to your Apple Card and more
iOS 18.1 will be here soon, and with it the first set of Apple Intelligence features. I recently discovered that one of the best new AI powers in iOS 18.1, notification summaries, can be a clever and helpful addition to the Apple Card and related spe.....»»
North Korean hackers use newly discovered Linux malware to raid ATMs
Once, FASTCash ran only on Unix. Then came Windows. Now it can target Linux, too. In the beginning, North Korean hackers compromised the banking infrastructure running AIX, IBM’.....»»
New venomous reptile species from the Late Triassic unearthed in Arizona
A new species of small, venomous reptile, Microzemiotes sonselaensis, has been discovered in the Late Triassic Chinle Formation in northeastern Arizona. The findings, recently published in PeerJ, shed new light on the evolution of venomous feeding st.....»»
Scientists discover chemical probes for previously "undruggable" cancer target
Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1). FOXA1 mutations can enable these types of cancers to grow and proliferate. Today, FOXA1 is notoriously diff.....»»
Bacteria discovered in healthy vertebrate brains point to a potential role in brain function
Researchers at the University of New Mexico have identified the presence of bacteria in the healthy brains of fish. Understanding this connection between bacteria and animal brains could have future implications for the study of Alzheimer's disease......»»
Seven new frog species discovered in Madagascar
An international team of researchers have discovered seven new species of tree frogs that make otherworldly calls in the rainforests of Madagascar. Their strange, high-pitched whistling calls sound more like sound effects from the sci-fi series "Star.....»»
Archaeologists discover Armenia"s oldest church
Archaeologists from the National Academy of Sciences of Armenia and the University of Münster have discovered the remains of a previously unknown early Christian church in the ancient city of Artaxata. The find consists of an octagonal building with.....»»
Smart gardening firm’s shutdown a reminder of Internet of Things’ fickle nature
Company closing "due to a number of challenges with this business." AeroGarden, which sells Wi-Fi-connected indoor gardening systems, is going out of business on January 1. While.....»»
Giant prehistoric elephant skull from India belongs to mysterious extinct species
The giant fossil skull of an extinct elephant, discovered in northern India's Kashmir Valley in 2000, sheds light on a poorly known episode in elephant evolutionary history......»»
Glowing proteins enable real-time, 3-D study of essential enzymes
Working in organoid models, researchers at University of California San Diego School of Medicine have developed a new tool to study protein-kinase C (PKC) enzymes, which play a critical role in cell growth, differentiation and survival. Malfunction o.....»»
Digital quantum simulation of nuclear magnetic resonance experiments
Programmable quantum computers have the potential to efficiently simulate increasingly complex molecular structures, electronic structures, chemical reactions, and quantum mechanical states in chemistry that classical computers cannot. As the molecul.....»»
Calcium transport protein in bacteria offers insights for drug development and food safety
Researchers at Umeå University have revealed details on how bacteria use calcium to regulate vital processes in a way that differs from human cells. This breakthrough is significant in the fight against antibiotic resistance and for increasing safet.....»»