Molecular gardening: New enzymes discovered for protein modification pruning
Deubiquitinases (DUBs) are enzymes used by cells to trim protein modifications made from the protein ubiquitin, and thereby regulate proteins. Malfunctioning of DUBs could lead to diseases, including cancer and neurodegenerative disorders......»»
Enhancing recombinant protein expression in lettuce
Recombinant proteins are crucial in pharmaceutical and other industries. A production method uses plants as hosts in transient protein expression systems. Researchers at the University of Tsukuba developed a technique to increase recombinant protein.....»»
Promising triazole molecular catalyst enables efficient electroreduction of carbon dioxide to methane
The efficient conversion of carbon dioxide (CO2)—one of the main compounds contributing to climate change—into useful fuels and chemicals is a long sought-after research goal. Recent studies have introduced various catalysts that could be used to.....»»
Discovery of new bacterial toxins could be key to fighting infections
Researchers have discovered a new group of bacterial toxins that can kill harmful bacteria and fungi, opening the door to potential new treatments for infections. These toxins, found in over 100,000 microbial genomes, can destroy the cells of bacteri.....»»
Scientists uncover how transcription drives motion within the genome
A team of scientists has discovered surprising connections among gene activity, genome packing, and genome-wide motions, revealing aspects of the genome's organization that directly affect gene regulation and expression......»»
How plants compete for light: Researchers discover new mechanism in shade avoidance
Plants that are close together do everything they can to intercept light. This "shade avoidance" response has been extensively researched. It is therefore even more remarkable that researchers from the laboratory of Molecular Biology at Wageningen Un.....»»
"Nano-weapon" discovery boosts fight against antibiotic-resistant hospital superbugs
Researchers have discovered how a bacteria found in hospitals uses "nano-weapons" to enable their spread, unlocking new clues in the fight against antibiotic-resistant superbugs......»»
Astronomers explore the properties of an obscured hyperluminous quasar
Astronomers from the European University Cyprus and the University of Hawaii have investigated a recently discovered obscured hyperluminous quasar known as COS-87259. Results of the study, published October 14 in the Monthly Notices of the Royal Astr.....»»
Saturday Citations: Brown dwarf actually brown dwarfs; the adaptability of ice-age humans; archaeologists excited
This week, researchers discovered a near-Earth microquasar that sheds new light on sources of relativistic outflows. Doctors reported finding a triphallic gentleman. And neuroscientists reported on modest cognitive boosts from short (or "acute," in c.....»»
New strategy unlocks magnetic switching with hydrogen bonding at molecular level
A research team from Kumamoto University has successfully developed a new approach to create switchable magnetic materials by using hydrogen bonding at the molecular level. Their study shows how certain metal complexes, previously unresponsive to ext.....»»
Schools for the blind can have positive psychological transformative effects on people with visual impairment
Researchers at University of Tsukuba have discovered that for individuals with acquired visual impairments, "segregated placements," such as schools for the blind, play a significant role in fostering positive psychological transformation after the o.....»»
Research provides molecular insights into sexual dimorphism of chicken feathers
Birds possess unique skin appendages called feathers that are derived from the outermost layer of skin cells. Feathers are important for several functions, such as flight, temperature regulation, protection from external stimuli, and mating behavior......»»
Lignin molecular property discovery could help turn trees into affordable, greener industrial chemicals
Trees are the most abundant natural resource living on Earth's land masses, and North Carolina State University scientists and engineers are making headway in finding ways to use them as sustainable, environmentally benign alternatives to producing i.....»»
Molecular "cut and sew" process could accelerate drug design
A innovative molecular "cut and sew" process by University of Dundee scientists has allowed the design of a research tool that will accelerate drug design for diseases for which no other options exist, including cancer......»»
Single-molecule imaging reveals aberrant DNA-binding dynamics of cancer-linked chromatin remodelers
Biophysical chemists from the National University of Singapore (NUS) have uncovered a previously hidden landscape that governs the intracellular organization and dynamics of SWI/SNF chromatin remodelers, an important class of protein complexes that c.....»»
Fast super-resolved microscopy enables structured illumination and extended depth detection
Fluorescence microscopy is a powerful tool in biology, allowing researchers to visualize the intricate world of cells and tissues at a molecular level. While this technique has revolutionized our understanding of biological processes, imaging large a.....»»
Researchers find new role for protein in combating age-related diseases
McMaster University researchers have discovered a previously unknown cell-protecting function of a protein, which could open new avenues for treating age-related diseases and lead to healthier aging overall......»»
Discovery of key protein for biosynthesis of plant defense steroids could enhance pest control strategies
Researchers at the Max Planck Institute for Chemical Ecology have identified GAME15 as a key protein that regulates the biosynthesis of both steroidal glycoalkaloids and steroidal saponins in plants of the genus Solanum......»»
More efficient phenotypic screening method can simultaneously test multiple drugs
Some of the most widely used drugs today, including penicillin, were discovered through a process called phenotypic screening. Using this method, scientists are essentially throwing drugs at a problem—for example, when attempting to stop bacterial.....»»
Plankton balloon to six times their size in newly discovered mode of oceanic travel
Many plankton journey from the cold, dark depths of our oceans to the surface, only to eventually drift down again into the darkness in a perpetual rhythm. Yet, how single-celled phytoplankton, most of which have no appendages to help them swim, make.....»»
Protein signaling pathway provides insights into cell migration and cancer metastasis
The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a village: a combination of physical barriers, chemical attacks, and an army of specialized white blood cells. But maintaining and.....»»