Liver-targeting drug delivered via nanogel carrier reverses obesity, lowers cholesterol in mice
A University of Massachusetts Amherst biomedical engineer has used a nanogel-based carrier designed in his lab to deliver a drug exclusively to the liver of obese mice, effectively reversing their diet-induced disease......»»
I tested three travel eSIMs on a trip. It was more complicated than I thought
If you're traveling abroad, how do you stay connected? Do you use a travel eSIM, a local SIM, or your own carrier? I tested three eSIMs on a trip to find out......»»
Analysis provides new insights into the replication of BK polyomavirus, a major cause of kidney transplant failure
BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research at the University of Alabama at Birmingham reveals new aspects of BKPyV replication, offering possible drug targets to pro.....»»
Iran launches heaviest space payload into orbit: media
Iran successfully launched on Friday its heaviest space payload, which includes a satellite and a space tug, using a domestically developed satellite carrier, official media reported......»»
Broadcom reverses controversial plan in effort to cull VMware migrations
Broadcom will only hog 500 of VMware's biggest customers instead of 2,000. Broadcom will no longer take VMware's biggest 2,000 customers directly. Instead, it will work with VMwar.....»»
Peer-brokered sales central to illegal drug trade
The thought of illegal drug sales evokes images of deals done on shady street corners. But a new study from Case Western Reserve University exposes a critical but underreported element of the illegal drug market: so-called "peer-brokered" sales......»»
Russian court sentences kingpin of Hydra drug marketplace to life in prison
The underground marketplace distributed more than a metric ton of narcotics. A Russian court has issued a life sentence to a man found guilty of being the kingpin of a dark web dr.....»»
FortiAppSec Cloud simplifies web application security management
Fortinet announced FortiAppSec Cloud, a new cloud-delivered platform that integrates key web application security and performance management tools into a single offering. The platform streamlines web and API security, advanced bot defense, and global.....»»
Amazon launches its version of Spotify Wrapped with Amazon Music Delivered 2024
This year, Amazon released its own year-end version of Spotify Wrapped with Amazon Music Delivered 2024......»»
Open-source platform supports large imaging data analysis of single cell responses to manipulation
Modern day drug discovery is shifting from single end point assays to more complex phenotypic assays that query single cell and population responses to chemicals and genetic manipulation......»»
Wildlife commission lowers European wolf protections
Dozens of countries on Tuesday approved downgrading the protection status of the wolf in Europe, a move activists say will upset the recovery made by the species over the past 10 years after near extinction a century ago......»»
Study discovers a nano-switch mechanism controlled by a single hydrogen atom in all living organisms
A group of researchers in Japan has revealed, for the first time, a mechanism for controlling the potential of an electron carrier protein in the redox reaction that all organisms need to obtain energy. The study was published in the online edition o.....»»
New understanding of a cancer-relevant protein reveals opportunities for drug discovery
A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights into how it functions......»»
$400M seized, 5,500 arrested in global operation targeting cyber fraud
A coordinated international operation involving law enforcement agencies from 40 countries led to the arrest of over 5,500 individuals linked to financial crimes and the confiscation of more than $400 million in virtual assets and government-backed c.....»»
UK carrier Three supporting RCS for iPhone users from next month
Apple held out for a long time on switching from text messaging to RCS (rich communication services), but finally announced that it would be doing so as part of iOS 18. The move brings many iMessage-like features to text messages between iPhone and A.....»»
Modified ribosomes could be a possible mechanism of antibiotic resistance
Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published in Nature Communications. The subtle changes might be enough to alter the binding site of drug targets and constitute a possible new mechanism of.....»»
Parasite genome analysis provides a new approach to predicting malaria drug resistance
Researchers at University of California San Diego analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug resistance......»»
Scientists synthesize unsymmetrical ureas using non-phosgene method
Unsymmetrical ureas can form multiple stable hydrogen bonds with proteins. Since drugs containing urea functional groups display unique biological activities when interacting with their targets, they play an important role in drug development and med.....»»
Targeting bacterial defense mechanisms for effective antibiotic treatment
In addition to the urgent need for new antibiotics, alternative strategies are required to tackle the problem of antibiotic resistance. Michaela Wenzel, Associate Professor at Chalmers University of Technology, is investigating bacterial defenses aga.....»»
Apple unveils 2024 App Store Awards finalists
Apple has unveiled the app and game finalists for the 2024 App Store awards. Apple says these finalists represent “developers who delivered the highest levels of user experience, design, and innovation.” Head below for the full list… mo.....»»
Trump targets Mexico and Canada with tariffs, plus an extra 10% for China
Tariffs are retaliation for drug trafficking and illegal migration. Donald Trump has said he will impose tariffs of 25 percent on all imports from Canada and Mexico, and an extra.....»»