Key protein linked to appetite and obesity in mice
Researchers from the Okinawa Institute of Science and Technology Graduate University (OIST) have identified a protein that plays a key role in how the brain regulates appetite and metabolism. Loss of the protein, XRN1, from the forebrain, resulted in.....»»
5 best Netflix shows to stream this Labor Day weekend
Including comedy, politics, and sports to quench your appetite for lazy days off, check out the five best Netflix shows to stream this Labor Day weekend......»»
Researchers identify genes for low glycemic index and high protein in rice
A team of researchers at the International Rice Research Institute (IRRI) has identified genes and markers responsible for low glycemic index (GI) and high protein content in rice, using genetics and artificial intelligence classification methods......»»
Scientists unlock the secrets of how a key protein converts DNA into RNA
Researchers at the Department of Energy's SLAC National Accelerator Laboratory have uncovered new insights into the fundamental mechanisms of RNA polymerase II (Pol II), the protein responsible for transcribing DNA into RNA. Their study shows how the.....»»
Protein mutant stability can be inferred from AI-predicted structures
Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI......»»
Arctic heat waves linked to sea ice loss, new study reveals
Amid global warming, heat waves are striking even the Arctic, a region once considered immune to such extreme weather events. Recent research reveals that these heat waves, particularly in the Barents-Kara Sea (BKS) during the boreal autumn, are not.....»»
Study shows an electrically-activated protein regulates spermatogenesis
Frankenstein's monster was brought to life by the judicious application of a little electricity; and a surprising number of processes in our bodies are regulated by electrical currents too. Now, researchers from Japan reveal that electricity may play.....»»
Using metal ion-linked nanostructures to improve immune response and boost breast tumor treatment
Immune checkpoint blockade (ICB) is one of the primary methods of tumor immunotherapy. However, clinical data have shown that only a portion of patients respond to ICB treatment. Since the tumor's immune-suppressive environment plays a crucial role i.....»»
Massive nationwide meat-linked outbreak kills 5 more, now largest since 2011
CDC implores consumers to check their fridges for the recalled meats. Enlarge / Listeria monocytogenes. (credit: Getty | BSIP) Five more people have died in a nationwide outbreak of Listeria infections linked to contamin.....»»
Five more dead in record-breaking outbreak linked to Boar’s Head meats
CDC implores consumers to check their fridges for the recalled meats. Enlarge / Listeria monocytogenes. (credit: Getty | BSIP) Five more people have died in a nationwide outbreak of Listeria infections linked to contamin.....»»
Chloroplast manipulation: A new strategy in pathogen warfare uncovered
A recent study has unveiled the sophisticated methods pathogens use to weaken plant defenses. It shows how a pathogen's effector protein targets the chloroplast protein StFC-II, increasing its levels in chloroplasts and reducing the plant's ability t.....»»
Uncertainty is a key factor in the relationship between work injury and mental health, research shows
Mental health and workplace injuries are known to be closely linked, but there are significant gaps in our deeper understanding of that bidirectional relationship. How does one affect the other, what moderates the relationship and what are the long-t.....»»
Simulation model shows ribosome tunnel"s impact on protein structures
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»
Authors propose multi-method framework for climate event attribution
At the two most recent meetings of the United Nations Framework Convention on Climate Change, delegates agreed to establish a fund to help developing nations suffering loss and damage due to events linked to climate change, such as floods, heat waves.....»»
Dual protein analysis approach provides potential way to slow cancer growth
Fighting cancer effectively often involves stopping cancer cells from multiplying, which requires understanding proteins that the cells rely on to survive. Protein profiling plays a critical role in this process by helping researchers identify protei.....»»
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
Record-breaking drought in southern China linked to Eurasian warming and tropical sea surface temperature
Southern China experienced an extreme drought that persisted from summer to autumn in 2022, ranking as the most severe drought since 1980. The reason for the occurrence of this extreme drought event was investigated. It shows that both the Eurasian w.....»»
S.Africa plan to "bomb" mice that eat albatrosses alive
Conservationists said Saturday that they plan to bomb a remote South African island with tons of pesticide-laced pellets to kill mice that are eating albatrosses and other seabirds alive......»»
Research unravels dual role of membrane protein in rice ethylene signal transduction
A research team, led by Professor Zhang Jinsong from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences, revealed insights into the mechanism by which the membrane protein MHZ3 collaborates with the ethylene.....»»
A small molecular glue that increases P53 level and suppresses tumor growth in vivo
Molecular glues are typically small chemical molecules that act on the interface between the target protein and the degradation machinery to trigger ternary complex formation. Identification of molecular glues is challenging, and there has been a lac.....»»
Ancient microbes linked to evolution of human immune proteins
When you become infected with a virus, some of the first weapons your body deploys to fight it are those passed down to us from our microbial ancestors billions of years ago. According to new research from The University of Texas at Austin, two key e.....»»