How the pathogen Mycobacterium tuberculosis secretes and traffics its only known exotoxin
Six years ago, Michael Niederweis, Ph.D., described the first known toxin of the deadly pathogen Mycobacterium tuberculosis (Mtb), an exotoxin that had gone undetected for 132 years......»»
Pathogenic bacteria causing lung diseases hitchhike on red blood cells
Mycobacteria are a group of pathogenic bacteria that cause diseases like leprosy and tuberculosis in humans. Now, a new study by scientists at Hiroshima University finds that mycobacteria are associated with red blood cells at lung infection sites, a.....»»
TB antibiotic activity impacted by cell pH
Researchers at the Francis Crick Institute have shown that an antibiotic used to treat tuberculosis (TB) is affected by pH levels in the environment the bacteria has infected......»»
How the Chagas pathogen changes the intestinal microbiota of predatory bugs
In Central and South America, predatory blood-sucking bugs transmit the causative agent of the widely prevalent Chagas disease. As the disease can induce severe symptoms and to date there is no vaccine against the Trypanosoma parasites, the main appr.....»»
A new model of pathogen transmission in developing urban landscapes
Scientists from the International Livestock Research Institute (ILRI), the University of Liverpool, the University of Edinburgh and elsewhere have traced how diverse strains of a common pathogenic bacteria spread in Nairobi, Kenya, shedding light on.....»»
Exploring ancient tuberculosis transmission chains
Tuberculosis (TB) is the second most common cause of death worldwide by an infectious pathogen (after Covid-19), but many aspects of its long history with humans remain controversial. Researchers at the Max Planck Institute for Evolutionary Anthropol.....»»
Paper made from banana plants stymies potato pest
Wrapping potato seeds in biodegradable paper made from unusable parts of banana plants reduces the infestation and harmful effects of a nasty plant pathogen—a worm called the potato cyst nematode—and sharply increases potato size and yields......»»
Pathogen-repellent wrap shown to shed viruses as well as bacteria
New research by the inventors of a promising pathogen-repellent wrap has confirmed that it sheds not only bacteria, as previously proven, but also viruses, boosting its potential usefulness for interrupting the transmission of infections......»»
Grouping of immune cell receptors could help decode patients" personal history of infection
Novel software for grouping immunological T-cell receptors may enable the identification of shared patterns that could be used to determine if a person has previously been infected or vaccinated against a given pathogen......»»
Sediments a likely culprit in spread of deadly disease on Florida coral reefs, study finds
A new study found that seafloor sediments have the potential to transmit a deadly pathogen to local corals and hypothesizes that sediments have played a role in the persistence of a devastating coral disease outbreak throughout Florida and the Caribb.....»»
Bird Flu Is Back in the US. No One Knows What Comes Next
The fast-moving pathogen, which has already invaded Europe, was found in East Coast ducks. The last outbreak that tore through the US killed 50 million birds......»»
New structure prediction model has mapped 500 previously unsolved proteins
Scientists at the University of California, Berkeley, have recently published work that lays the foundation for new ways of thinking about pathogen evolution. "Our research highlights that template-free modeling that uses machine learning is indeed s.....»»
Scientists prove that deadly gene has jumped from a harmless organism to a nasty pathogen
University of South Australia scientists have made a surprising discovery in the origins of an antibiotic-resistant gene previously thought to have been confined to Adelaide......»»
Genetic discovery to improve breeding for disease resistance in wheat
Australian and European researchers have discovered a genetic element in a common wheat pathogen with potential to help streamline breeding for disease-resistant wheat varieties that are better suited to Australian conditions......»»
Affordable genome sequencing for pathogen analysis to help tackle global epidemics
A worldwide consortium of scientists, led by the Earlham Institute and the University of Liverpool in the UK, mark a significant milestone in equipping researchers in low- and middle-income countries (LMICs) with cheap and accessible methods for sequ.....»»
Study reveals how bacterial pathogen adapts to nutritional stress
In order to cause disease, the human pathogen Staphylococcus aureus must adapt to the changing host environment. Many of these adaptations are mediated through two-component signal transduction systems (TCSs) that coordinate gene expression in respon.....»»
Plant pathogen evades immune system by targeting the microbiome
A team of biologists has identified that the pathogenic fungus Verticillium dahliae, responsible for wilt disease in many crops, secretes an 'effector' molecule to target the microbiome of plants to promote infection. The research was performed by th.....»»
First study of its kind to investigate a high priority but little known pathogen found in Irish hospitals
By understanding the epidemiology and population biology of a significant and high-priority pathogen, Enteroccocus faecium (E. faecium) in Irish hospitals, researchers are providing the evidence base for more effective surveillance, and infection and.....»»
New details behind how the Shigella pathogen delivers bacterial proteins into our cells
Scientists have advanced knowledge about how two proteins fit together to form a pore that Shigella uses to invade intestinal cells. Targeting these proteins could hamper infection by this bacterial pathogen......»»
How the pathogen Mycobacterium tuberculosis secretes and traffics its only known exotoxin
Six years ago, Michael Niederweis, Ph.D., described the first known toxin of the deadly pathogen Mycobacterium tuberculosis (Mtb), an exotoxin that had gone undetected for 132 years......»»
New details behind how the Shigella pathogen delivers bacterial proteins into our cells
Shigella, a bacterial pathogen that causes dysentery and is the leading cause of childhood diarrheal diseases, inserts a pore called a translocon into an infected person's intestinal cells and then injects bacterial proteins into the cells. There, th.....»»