How the pathogen Mycobacterium tuberculosis secretes and traffics its only known exotoxin
Six years ago, Michael Niederweis, Ph.D., described the first known toxin of the deadly pathogen Mycobacterium tuberculosis (Mtb), an exotoxin that had gone undetected for 132 years......»»
African giant rats trained to sniff out illegal wildlife products
In the past, African giant pouched rats have learned to detect explosives and the tuberculosis-causing pathogen. Now, a team of researchers have trained these rats to pick up the scent of pangolin scales, elephant ivory, rhino horn, and African black.....»»
Scientists uncover key mechanism in pathogen defense, paving way for new antimicrobial strategies
Researchers have made a significant breakthrough in understanding how certain pathogens defend themselves against the host's immune system......»»
Bacterial pathogen must balance between colonizing airways and developing antibiotic tolerance, study reveals
Imagine trying to settle into a new home while constantly being attacked. That's what the bacterium Pseudomonas aeruginosa faces when it infects the lungs, and it can't both spread and protect itself from antibiotics at the same time......»»
Study shows weak external electric fields may protect crops from infection
Research from Dr. Giovanni Sena's group in the Department of Life Sciences highlights an intriguing method to help protect plants from pathogen attacks using weak electric fields......»»
Artificial "nose" can sniff out damaged fruit and spoiled meat
Although smell has historically played an important role in the fight against diseases such as the plague and tuberculosis, the human nose is generally not sensitive enough to be used as a reliable diagnostic tool. However, a new artificial "nose" in.....»»
Chemical trick activates antibiotic directly at the pathogen
Colistin is a last-resort antibiotic that is usually only used for severe infections with resistant bacteria. This is due to its severe kidney-damaging side effects, which occur in about 30% of treated patients. A research team at the Helmholtz Cente.....»»
A unified theory for predicting pathogen competition: Exploring how emerging new strains replace previous ones
The COVID-19 pandemic showed that predicting the invasion of a novel pathogen into the human population and its evolutionary potential to generate new variants is crucial for preventing future outbreaks. New research conducted at Princeton University.....»»
Study sheds light on limitations of zooplankton for inactivating pathogen contaminated water
Scientists at The University of Texas at El Paso and Stanford University were recently surprised to find that the natural community of zooplankton—tiny, aquatic animals known to graze on bacteria—present in freshwater and saltwater do not clean w.....»»
How a bacterial pathogen that causes dysentery manipulates molecular activity to assure its survival
Virginia Tech researchers have learned how bacteria manipulate molecules to infect the host organism. Daniel Capelluto and his research team have discovered the mechanism by which the bacterial pathogen Shigella flexneri, the causative agent of dysen.....»»
Plant pathogen battle: A tomato protein"s dual role in defense and susceptibility
Tomatoes, a staple crop worldwide, are increasingly threatened by biotic stressors such as viruses, fungi, and bacteria, with the effects worsening under climate change. These challenges lead to reduced yields and compromised nutritional quality, hig.....»»
Unlocking plant defense: Bacterial hijacking exposed
Bacterial wilt caused by Ralstonia solanacearum poses a severe threat to agriculture worldwide, affecting numerous crops. The pathogen's arsenal of type III effectors (T3Es) enables it to manipulate host defense mechanisms, aiding infection. One majo.....»»
Tuberculosis under the sea: A marine sponge microbe provides insights into the bacterium"s evolution
The surprising discovery of a bacterium in a marine sponge from the Great Barrier Reef with striking similarity to Mycobacterium tuberculosis, the pathogen responsible for tuberculosis (TB), could unlock and inform future TB research and treatment st.....»»
Chloroplast manipulation: A new strategy in pathogen warfare uncovered
A recent study has unveiled the sophisticated methods pathogens use to weaken plant defenses. It shows how a pathogen's effector protein targets the chloroplast protein StFC-II, increasing its levels in chloroplasts and reducing the plant's ability t.....»»
Study analyzes potato-pathogen "arms race" after Irish potato famine
In an examination of the genetic material found in historic potato leaves, North Carolina State University researchers reveal more about the tit-for-tat evolutionary changes occurring in both potato plants and the pathogen that caused the 1840s Irish.....»»
Woman who went on the lam with untreated TB is now cured
The woman realized how serious her infection was once she was in custody. Scanning electron micrograph of Mycobacterium tuberculosis bacteria, which cause TB. (credit: National Institute of Allergy and Infectious Diseases).....»»
Study: Vps21 signaling pathway regulates white-opaque switching and mating in Candida albicans
In a paper published in Mycology, a team of scientists present that the conserved Vps21 signaling pathway plays critical roles in the regulation of white-opaque switching and mating in the major human fungal pathogen C. albicans......»»
Study finds pumpkin pathogen not evolving, which could make a difference for management
The pathogen that causes bacterial spot is very good at what it does. Forming small lesions on the rinds of pumpkins, melons, cucumbers, and other cucurbits, it mars the fruits' appearance and ushers in secondary pathogens that lead to rot and severe.....»»
Certain bacteria or fungi could combat a plant pathogen that attacks common vetch
Anthracnose, a severe disease caused by the Colletotrichum spinaciae plant pathogen, often occurs in common vetch, a widely grown legume. Chemicals are not recommended for disease management because the plants are used as livestock feed. A new study.....»»
Researchers reveal how myrtle rust pathogen breaks into a host plant
A recent study looking at the molecular foundation of myrtle rust reveals how the pathogen breaks into a host plant and how the host plant responds. This insight will inform the design of useful tools to prevent future break-ins and safeguard plant h.....»»
Researchers develop tool for detecting foodborne pathogen that causes severe symptoms in children
The prevalence of pathogenic E. coli has meant the frequent misidentification of a similar bacterium of the Escherichia genus. E. albertii is an emerging zoonotic foodborne pathogen, first isolated in Bangladesh in 1991. Large-scale outbreaks of food.....»»