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New details behind how the Shigella pathogen delivers bacterial proteins into our cells

Shigella, a bacterial pathogen that causes dysentery and is the leading cause of childhood diarrheal diseases, inserts a pore called a translocon into an infected person's intestinal cells and then injects bacterial proteins into the cells. There, th.....»»

Category: topSource:  physorgNov 23rd, 2021

A shortcut for drug discovery: Novel method predicts on a large scale how small molecules interact with proteins

For most human proteins, there are no small molecules known to bind them chemically (so-called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel.....»»

Category: topSource:  physorgRelated News15 hr. 3 min. ago

Apple Card teams up with Nike for 10% cash back

Apple Card has shared its latest promotion for customers – 10% Daily Cash up to $50 back on purchases at Nike. Here are the details… more….....»»

Category: topSource:  informationweekRelated News18 hr. 2 min. ago

Study reveals protein"s key role in helping cilium transmit signals to the rest of the cell

The essential role played by a protein in the functioning of cells is revealed in new work from the laboratory of Université de Montréal medical professor Frédéric Charron, holder of the Canada Research Chair in Developmental Neurobiology......»»

Category: topSource:  physorgRelated News18 hr. 35 min. ago

Scientists regenerate neural pathways in mice with cells from rats

Two independent research teams have successfully regenerated mouse brain circuits in mice using neurons grown from rat stem cells. Both studies, published April 25 in the journal Cell, offer valuable insights into how brain tissue forms and present n.....»»

Category: topSource:  physorgRelated News18 hr. 35 min. ago

IRIS beamline at BESSY II gets a new nanospectroscopy end station

The IRIS infrared beamline at the BESSY II storage ring now offers a fourth option for characterizing materials, cells and even molecules on different length scales. The team has extended the IRIS beamline with an end station for nanospectroscopy and.....»»

Category: topSource:  physorgRelated News18 hr. 35 min. ago

Toyota invests $1.4 billion in Indiana plant for large EV

The investment will add 340 jobs and a new battery pack assembly line, but details signal that either the Toyota Sienna or Toyota Highlander will become a full EV in 2026......»»

Category: topSource:  autonewsRelated News19 hr. 3 min. ago

Spotify: Apple has ‘defied’ the EU by blocking latest update with pricing info [U: Apple response]

Yesterday we learned that Spotify decided to pass on Apple’s new EU terms that would allow it to use alternative payment methods due to the Core Technology Fee. Instead, it submitted an app update with pricing info and details on how to subscribe o.....»»

Category: topSource:  marketingvoxRelated News21 hr. 2 min. ago

Study suggests that cells possess a hidden communication system

Cells constantly navigate a dynamic environment, facing ever-changing conditions and challenges. But how do cells swiftly adapt to these environmental fluctuations?.....»»

Category: topSource:  physorgRelated NewsApr 24th, 2024

A shade closer to more efficient organic photovoltaics

Transparent solar cells will transform the look of infrastructure by enabling many more surfaces to become solar panels. Now, materials called non-fullerene acceptors that can intrinsically generate charges when exposed to sunlight could make semitra.....»»

Category: topSource:  physorgRelated NewsApr 24th, 2024

Imaging technique shows new details of peptide structures

A new imaging technique developed by engineers at Washington University in St. Louis can give scientists a much closer look at fibril assemblies—stacks of peptides that include amyloid beta, most notably associated with Alzheimer's disease......»»

Category: topSource:  physorgRelated NewsApr 24th, 2024

Unveiling the mysteries of cell division in embryos with timelapse photography

The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis are well-studied in the so-called somatic cells—the cells that have a specialized function, like skin and muscle cells—they remain elusive in the first cells of.....»»

Category: topSource:  physorgRelated NewsApr 24th, 2024

Biomolecular condensates: Study reveals poor predictive power of established liquid-liquid phase separation assays

Cells buzz with millions of different biomolecules that diffuse chaotically through their substructures, yet they manage to ensure exquisite functional and spatial specificity......»»

Category: topSource:  physorgRelated NewsApr 24th, 2024

PoC for critical Progress Flowmon vulnerability released (CVE-2024-2389)

More details of and a proof-of-concept exploit for an unauthenticated OS command injection vulnerability (CVE-2024-2389) in Flowmon, Progress Software’s network monitoring/analysis and security solution, have been published. The critical vulner.....»»

Category: securitySource:  netsecurityRelated NewsApr 24th, 2024

Cybersecurity jobs available right now: April 24, 2024

Blockchain Security Researcher StarkWare | Israel | On-site – View job details The Security Researcher will be responsible for conducting in-depth research and analysis on the security of blockchain systems, protocols and the infrastr.....»»

Category: securitySource:  netsecurityRelated NewsApr 24th, 2024

Scientists study lipids cell by cell, making new cancer research possible

Imagine being able to look inside a single cancer cell and see how it communicates with its neighbors. Scientists are celebrating a new technique that lets them study the fatty contents of cancer cells, one by one......»»

Category: topSource:  theglobeandmailRelated NewsApr 23rd, 2024

AirTags range: here’s how far the tracker can reach

How far can your iPhone track an Apple AirTag? Perhaps a lot further than you ever imagined thanks to the Find My Network. Here are the details......»»

Category: topSource:  digitaltrendsRelated NewsApr 23rd, 2024

Researchers create artificial cells that act like living cells

In a new study published in Nature Chemistry, UNC-Chapel Hill researcher Ronit Freeman and her colleagues describe the steps they took to manipulate DNA and proteins—essential building blocks of life—to create cells that look and act like cells f.....»»

Category: topSource:  theglobeandmailRelated NewsApr 23rd, 2024

Supercomputer simulation reveals new mechanism for membrane fusion

An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world's most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse......»»

Category: topSource:  physorgRelated NewsApr 23rd, 2024

Researchers report on mechanisms of gene regulatory divergence between species

Closely related animal species can look physically different, but you might be surprised to learn that those differences can result not only from DNA sequence changes that alter proteins' structure or function, but also because changes in the DNA aff.....»»

Category: topSource:  physorgRelated NewsApr 23rd, 2024

Researchers map protein network dynamics during cell division

An international team led by researchers at the University of Toronto has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the.....»»

Category: topSource:  physorgRelated NewsApr 22nd, 2024