How the epigenetic landscape modulates pioneer transcription factor binding
Like thread tightly wrapped around a spool, DNA is wrapped around histones and packaged into structures called nucleosomes. Scientists at St. Jude Children's Research Hospital are exploring how a type of transcription factor called a pioneer transcri.....»»
New genetic sensor for DNA methylation discovered
DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and is a major way that DNA is epigenetically marked. Epigenetic modifications can act as on–off switches to regulate gene expression and hel.....»»
At Honeymoon Island State Park, urgency grows to defend "the real Florida"
For Terry Fortner, the fight to save Honeymoon Island State Park from proposed development is personal. Nearly 130 years ago, just offshore from here, her grandmother Myrtle Scharrer was born in a pioneer home on Caladesi Island. She lived for decade.....»»
Experts meet as final global plastic treaty talks near
With months until crunch talks on the world's first binding treaty on plastic pollution, experts are meeting in Bangkok to discuss financing options and problematic plastics......»»
Gearbox founder says Epic Games Store hopes were “misplaced or overly optimistic”
Pitchford's prediction that Steam could be "a dying store" have not come to pass. Enlarge / Artist's conception of Randy Pitchford surveying the Epic Games Store landscape years after Borderlands 3's exclusive launch there. (cred.....»»
Canadian government intervenes in railway labor dispute
Federal Labor Minister Steven MacKinnon to use powers under Section 107 of the Labor Code to ask the Canada Industrial Relations Board to impose final, binding arbitration.....»»
Pollution drives families to relocate—but only the rich can afford to live in healthier areas
Pollution levels factor in households' decision to relocate within the United States, but only richer households can afford areas with improved air quality, a new study finds......»»
Here are 7 widgets that make StandBy Mode worth using [video]
StandBy Mode was introduced to us with the release of iOS 17. It gave the iPhone this passive but dynamic viewing mode when charging and in landscape mode. It can be used as a clock, to see the weather, as a hub for the Home app, or to help avoid dis.....»»
A European lander could return an ice core for a fraction of the cost of Europa Clipper
Cost is a major driving factor in the development of space exploration missions. Any new technology or trick that could lower the cost of a mission makes it much more appealing for mission planners. Therefore, much of NASA's research goes into those.....»»
Weather patterns as a major contributing factor to complex air pollution
"Complex pollution" usually refers to the environmental pollution phenomenon formed by the simultaneous presence of multiple pollutants in the same environment. In China, the issue of controlling the complex air pollution of fine particulate matter (.....»»
Upgraders concerned about iPhone 16 pricing, Apple Intelligence features
Most potential upgraders will find pricing to be a big factor in moving to the iPhone 16, a survey claims, with the introduction of Apple Intelligence almost as important.A render of what could be the iPhone 16 ProWith the iPhone 16 range set to laun.....»»
Mandatory MFA for Azure sign-ins is coming
Microsoft is making multi-factor authentication (MFA) – “one of the most effective security measures available” – mandatory for all Azure sign-ins. Preparing for mandatory MFA for Azure The plan is for the shift to happen in t.....»»
Tree mortality may lead to carbon tipping point in the Amazon by 2050s
The Amazon rainforest is home to a diverse cast of plants and animals. This vital, verdant landscape also plays a crucial role in managing the effects of climate change by storing significant amounts of carbon and helping regulate temperatures and ra.....»»
Renewable energy policies provide benefits across state lines, study shows
While the U.S. federal government has clean energy targets, they are not binding. Most economically developed countries have mandatory policies designed to bolster renewable electricity production. Because the U.S. lacks an enforceable federal mandat.....»»
ClearSale introduces three solutions to protect businesses from fraud
ClearSale has announced a new portfolio of fraud prevention tools designed to meet the evolving needs of today’s digital retail landscape. The newly launched suite, dubbed “Preventative Intel,” introduces three powerful solutions: I.....»»
Current attacks, targets, and other threat landscape trends
In this Help Net Security video, Kendall McKay, Strategic Lead, Cyber Threat Intelligence at Cisco Talos, discusses the trends that Cisco Talos incident response observed in incident response engagements from Q2 2024, which covers April to June. Whil.....»»
2025 iPhone SE with iPhone 14 form factor and Apple Intelligence sounds like a winner
All reports point to the 2025 iPhone SE being a huge upgrade from the 2022 model, but the more we hear about it, the more it looks set to prove a very viable option for those who want a modern iPhone without paying flagship prices. A reasonably co.....»»
Archaeologists conduct first "space excavation" on ISS and discover surprising quirks of zero-G life
New results from the first archaeological fieldwork conducted in space show the International Space Station is a rich cultural landscape where crew create their own "gravity" to replace Earth's, and adapt module spaces to suit their needs......»»
First map of vegetation across Antarctica reveals a battle for the continent"s changing landscape
A tiny seed is stuck between loose gravel and coarse sand. There is nothing else alive around it. All it can see is a wall of ice reaching 20 meters up into the sky. It is cold. Survival is hard around here. In winter, it is dark even during the day......»»
FoMO is a key risk factor for mental health and burnout at work
Fear of missing out (FoMO) is a key risk factor for employee mental health and, along with information overload, may increase burnout, according to new research......»»
Researchers develop AI model that predicts the accuracy of protein–DNA binding
A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the t.....»»