How the epigenetic landscape modulates pioneer transcription factor binding
Like thread tightly wrapped around a spool, DNA is wrapped around histones and packaged into structures called nucleosomes. Scientists at St. Jude Children's Research Hospital are exploring how a type of transcription factor called a pioneer transcri.....»»
Conservative governments protect more land while socialists and nationalists label more species as "threatened"
The dire state of biodiversity across the globe suggests that not all governments are willing to act decisively to protect nature. Why is that the case, and is a country's political ideology a factor?.....»»
Research team designs efficient bioenergy crops that need less water to grow
Drought stress has long been a limiting factor for crop production around the world, a challenge exacerbated by climate change......»»
Audio transcription compared -- Cloud-based vs. on-device
In iOS 18, Apple's Notes and Voice Memos apps get a new audio transcription feature. Here's everything you need to know about the different types of audio transcription, how they compare, and what Apple's implementation brings to the table.You can tr.....»»
Providing blooms all season long may be key to attracting pollinators, no matter what landscape is near your garden
A diverse and abundant flower planting that provides flowers in bloom all season may be more important to bees and other pollinators than whatever is surrounding the flower garden, according to a study published September 4, 2024 in PLoS ONE by Devon.....»»
Recreated 1870s railway photos reveal profound changes to Kansas and Colorado plains
A new book chronicling transformation on the plains of Kansas and western Colorado uses repeat photography—contemporary re-creations of 1870s photos—to reveal startling changes to the landscape......»»
Metal bats have pluses for young players, but in the end it comes down to skill
Skill of the hitters was still the biggest factor in how fast the ball came off the bat. Enlarge / Washington State University scientists conducted batting cage tests of wood and metal bats with young players. (credit: YouTube/Ba.....»»
Upcoming M4-based Mac mini rumored to replace USB-A with more USB-C ports
The forthcoming M4 Mac mini redesign is expected to follow iMac's lead and ditch USB-A ports, in favor of an array of USB-C ports.The current Mac mini form factor may change dramatically in its M4 incarnation.A new report from Bloomberg follows up on.....»»
YubiKeys are vulnerable to cloning attacks thanks to newly discovered side channel
Sophisticated attack breaks security assurances of the most popular FIDO key. Enlarge (credit: Yubico) The YubiKey 5, the most widely used hardware token for two-factor authentication based on the FIDO standard, contains.....»»
Mass cytometry barcoding strategy offers a new perspective of non-specific binding
Non-specific binding (NSB), the most annoying thing to scientists in the biosensing field, is one of the main factors limiting the performance of diagnostic sensors......»»
Yosemite National Park: Crews restore damaged landscape back to conditions not seen in 150 years
Yosemite National Park is famous for towering waterfalls, giant sequoia trees and massive granite cliffs. But at an out-of-the-way spot near the park's western boundary few visitors ever see, a landmark of a different type is taking shape......»»
Christa McAuliffe, still pioneering, is first woman with a statue on New Hampshire capitol grounds
Decades after she was picked to be America's first teacher in space, Christa McAuliffe is still a pioneer—this time as the first woman to be memorialized on the grounds of New Hampshire's Statehouse, in the city where she taught high school......»»
Cells use alternative splicing to regulate gene expression, research suggests
Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism increases the diversity of proteins that can be generat.....»»
AI company Midjourney teases hardware product in a new form factor
It hired a hardware chief who previously worked on Apple Vision Pro. Responding to this meme image of a wizard with an orb from the I.C.E. book Middle-earth: Valar and Maiar, Midjourney's founder joked that the new hardware form.....»»
ESPN’s Where to Watch tries to solve sports’ most frustrating problem
Find your game in a convoluted landscape of streaming services and TV channels. The ESPN app on an iPhone 11 Pro. (credit: ESPN) Too often, new tech product or service launches seem like solutions in search of a problem,.....»»
Study finds flexibility and helical twists of actin filaments regulate actin-binding proteins
Researchers at Kanazawa University have published an article in eLife deciphering the actin structure-dependent preferential cooperative binding of cofilin......»»
Pioneer Kitten: Iranian hackers partnering with ransomware affiliates
A group of Iranian hackers – dubbed Pioneer Kitten by cybersecurity researchers – is straddling the line between state-contracted cyber espionage group and initial access provider (and partner in crime) for affiliates of several ransomwar.....»»
Uncertainty is a key factor in the relationship between work injury and mental health, research shows
Mental health and workplace injuries are known to be closely linked, but there are significant gaps in our deeper understanding of that bidirectional relationship. How does one affect the other, what moderates the relationship and what are the long-t.....»»
South Asia air pollution fell in 2022, but remains major killer: report
A surprise improvement in air quality in South Asia in 2022 drove a decline in global pollution, with favorable weather a likely factor, a new report said Wednesday......»»
Discovery of a hidden epigenetic clock in mitochondria reveals a "lifespan limit line"
Building on their work on epigenetics of aging and transposable elements, researchers Dr. Ádám Sturm and Dr. Tibor Vellai from Eötvös Loránd University have made another advance in understanding the molecular mechanisms of aging. Their latest st.....»»
New genetic sensor for DNA methylation discovered
DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and is a major way that DNA is epigenetically marked. Epigenetic modifications can act as on–off switches to regulate gene expression and hel.....»»