How nitrate regulates gene expression in legumes
Plants in the bean family (legumes) form nodules on their roots to take up nitrogen. Legumes will stop nodule production when nitrogen is plentiful (Figure 1), but precisely how nitrate presence controls nodule formation in these plants has been a my.....»»
Study finds ways to enhance transcription factor activity
Transcription factors regulate gene expression by binding specific sequences on DNA, which is an essential step to producing messenger RNAs from protein-coding genes. Denes Hnisz's lab, in collaboration with Martin Vingron's lab at the MPIMG, has dis.....»»
Ex-Apple lawyer guilty of insider trading fined 10% of net worth
Gene Levoff was meant to police insider trading at Apple, but was caught in the act, found guilty, and given four years probation. He's now been fined $1.15 million in a related SEC case.Gene LevoffApple's former lawyer has had a rough time since he.....»»
Researchers capture never-before-seen view of gene transcription
Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one.....»»
Gene-Edited Salad Greens Are Coming to US Stores This Fall
Biotech giant Bayer plans to distribute mustard greens that have been genetically altered to make them less bitter to grocery stores across the country......»»
Mutations in a non-coding gene associated with intellectual disability
A gene that only makes an RNA is linked to neurodevelopmental problems. Enlarge / The spliceosome is a large complex of proteins and RNAs. (credit: NCBI) Almost 1,500 genes have been implicated in intellectual disabiliti.....»»
Researchers uncover protein SRSF1"s uncommon ability to bind and unfold RNA G-quadruplexes
RNA transcription is the genomic process in which a cell produces a duplicate of a gene's DNA sequence. In a study published in Nucleic Acids Research, University of Alabama at Birmingham Department of Chemistry Professor Jun Zhang, Ph.D., and his te.....»»
New modified CRISPR protein can fit inside virus used for gene therapy
Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells. Hongjian Wang and colleagues a.....»»
Study shows transgenic expression of rubisco factors increases photosynthesis and chilling tolerance in maize
Maize is one of the world's most widely grown crops and is essential to global food security. But like other plants, its growth and productivity can be limited by the slow activity of Rubisco, the enzyme responsible for carbon assimilation during pho.....»»
Innovative Thinking Could Make New Sickle Cell Treatments More Accessible
The cost of new gene-based sickle cell treatments isn’t the only barrier to access. Coming up with new ways to treat the whole disease—and person—could make treatment more equitable.....»»
Researchers reveal how acetylation regulates centromere dynamics, chromosome segregation and mitotic progression
Cell division produces new cells, which underpin life proliferation and development. Mitosis is the shortest and the most dynamic phase of the cell cycle. During mitosis, chromosomes are evenly distributed between the two daughter cells, preserving t.....»»
Gene could unlock greater wheat yields for a growing population
A study from the University of Adelaide has discovered molecular pathways regulated by a gene traditionally used to control wheat-flowering behavior could be altered to achieve greater yields. The research was published in Current Biology......»»
Study finds mitochondrial phosphate carrier plays an important role in virulence of Candida albicans
In a paper published in Mycology, Professor Yan Wang's team found that in both nematode and murine infection models, the lack of MIR1 gene, which encodes mitochondrial phosphate carrier, can lead to severe virulence defects in Candida albicans......»»
Researchers identify gene important to adaptation and determine roots are a key to drought-tolerant maize
An international study headed by the University of Bonn has now demonstrated the important role of the plant root system in maize, a crop that can grow successfully in very different local conditions......»»
iPhone 15 Pro Incase Woolenex and Vegan Leather ICON MagSafe case hands-on
Incase has been a favorite Apple accessory brand for me since before my time at 9to5Mac started in 2013. Seriously, their steel-colored Bird’s Nest Snap iPhone 4 case was the perfect blend of chaos and expression for me in 2011. Fast-forward to 202.....»»
Peach perfection: Advanced gene networks reveal fruit traits
A study has tapped into the peach genome, creating large-scale gene co-expression networks (GCNs) that predict gene functions and streamline the peach breeding process. This innovative approach addresses the complex task of identifying genes linked t.....»»
Study finds saying "please" may not be so polite in everyday requests
By kindergarten age, most children have been taught that "please" is a magic word. "Please" is an expression of politeness that shows courtesy and respect, turning a potential demand into a request that will—poof!—magically be granted......»»
Researchers clone "half-tendrilless" gene locus in pea mutant afila
Pea is the fourth largest edible legume crop in the world and is widely cultivated throughout the world. Several classical leaf mutants have been identified in peas, including unifoliata (uni), afila (af), tendril-less (tl), cocholeata (coch), stipul.....»»
More children gain hearing as gene therapy for profound deafness advances
The therapy treats a rare type of deafness, but experts hope it's a "jumping point." Enlarge / Opal Sandy (center), who was born completely deaf because of a rare genetic condition, can now hear unaided for the first time after r.....»»
Team develops an epigenome editing toolkit to dissect the mechanisms of gene regulation
Understanding how genes are regulated at the molecular level is a central challenge in modern biology. This complex mechanism is mainly driven by the interaction between proteins called transcription factors, DNA regulatory regions, and epigenetic mo.....»»
Nanoparticle researchers develop microfluidic platform for better delivery of gene therapy for lung disease
Drug delivery researchers at Oregon State University have developed a device with the potential to improve gene therapy for patients with inherited lung diseases such as cystic fibrosis......»»