New modified CRISPR protein can fit inside virus used for gene therapy
Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells. Hongjian Wang and colleagues a.....»»
Satechi 6-in-1 Slim USB-C Adapter review: Few ports, fewer complaints
The Satechi 6-in-1 Slim USB-C adapter is small enough to fit in the pocket but provides enough connectivity to support your day-to-day needs.Satechi 6-in-1 Slim USB-C Adapter reviewAfter upgrading from an iPhone 14 to an iPhone 16 this fall, all my d.....»»
After decades of talk, Seagate seems ready to actually drop the HAMR hard drives
At least one gigantic cloud provider has signed off on the drives' viability. How do you fit 32 terabytes of storage into a hard drive? With a HAMR. Seagate has been experimenting.....»»
Unlocking the brain: Peptide-guided nanoparticles deliver mRNA to neurons
Penn Engineers have modified lipid nanoparticles (LNPs)—the revolutionary technology behind the COVID-19 mRNA vaccines—to not only cross the blood-brain barrier (BBB) but also to target specific types of cells, including neurons. This breakthroug.....»»
Novel platinum complex shows strong antiproliferative effects with low toxicity in preclinical prostrate cancer models
Prostate cancer remains a global health challenge, ranking as the second most commonly diagnosed cancer among men. Although treatments like androgen deprivation therapy have been effective for early-stage prostate cancer, advanced stages, such as cas.....»»
New method speeds up protein study, aiding disease treatment research
Protein complexes are important for the majority of vital processes in the cell and human body, such as producing energy, copying DNA and regulating the immune system......»»
Protein"s "hopping" behavior uncovers new drug development avenues
Since 2006, Ruben Gonzalez's Columbia lab has used single-molecule light microscopy to study the structural dynamics of biomolecules......»»
Uncovering the evolutionary origins of the hepatitis E virus
An international team of virologists, mammalian ecologists and zoologists has uncovered the evolutionary origins of the hepatitis E virus. In their study, published in the Proceedings of the National Academy of Sciences, the group analyzed genomic da.....»»
Study shows diverse virus populations coexist on single strains of gut bacteria
Viruses that infect and kill bacteria, called phages, hold promise as new treatment types for dangerous infections, including strains that have become resistant to antibiotics. Yet, virologists know little about how phages persist in the populations.....»»
Studies pin down exactly when humans and Neanderthals swapped DNA
We may owe our tiny sliver of Neanderthal DNA to just a couple of hundred Neanderthals. Two recent studies suggest that the gene flow (as the young people call it these days) betw.....»»
How influenza A moves: New simulation offers potential to stop spread
A team of bioengineers from the Biohub at the University of California, Berkeley, and the Chan Zuckerberg Initiative has created a simulation to mimic the way the influenza A virus moves through host tissue, presenting a possible new way to stop the.....»»
Mosquito genetics may explain why Zika virus outbreaks are rare in Africa: Climate change could shift the balance
A study reveals that Africa's low rates of Zika virus outbreaks may be due to a surprising factor: the genetic makeup of local mosquito populations......»»
Apple issues updates for iPadOS 17, macOS Ventura, Sonoma
As part of Apple's operating system update releases, it has also brought out updates for older iPadOS and macOS generations for the public to install.An iMac running an older macOS versionWhile the main focus of software updates is on the latest gene.....»»
BadRAM: $10 hack unlocks AMD encrypted memory
Cybersecurity researchers have identified a vulnerability (CVE-2024-21944, aka BadRAM) affecting ADM processors that can be triggered by rogue memory modules to unlock the chips’ encrypted memory. The SPD chip can be modified using an off-the-s.....»»
Google Pixel Buds and Sony LinkBuds are both on sale at Best Buy
Enjoy your favorite music and podcasts with the Google Pixel Buds Pro 2 and Sony LinkBuds Fit. Right now, both pairs of ANC earbuds are on sale at Best Buy!.....»»
The first trailer for 28 Years Later has arrived, and it’s downright terrifying
In the first trailer for 28 Years Later, the Rage Virus continues to wreak havoc as the zombie apocalypse only gets worse......»»
US to start nationwide testing for H5N1 flu virus in milk supply
Feds can compel any company that handles pre-pasteurized milk to share samples. On Friday, the US Department of Agriculture (USDA) announced that it would begin a nationwide testi.....»»
Detecting problems during protein synthesis with a firefly luciferase-based reporter
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER), as reported by researchers at Science Tokyo. Inspired by natural mechanisms found in bacteria, th.....»»
Computer modeling shows close encounters between distant DNA regions cause bursts of gene activity
Researchers at Kyushu University have revealed how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer modeling, the researchers showed that the folding and moveme.....»»
Nanoparticle-mediated gene therapy fixes major cause of stillbirth and premature birth in guinea pig model
The life of billions of people inhabiting Earth is owed to a temporary organ that supported and nourished them in a mother's womb. The placenta, or afterbirth, is considered sacred by some cultures, its pivotal role in pregnancy recognized as far bac.....»»
Method enhances solubility of pea protein for use in food and beverages
Research conducted at the State University of Campinas (UNICAMP) in São Paulo state, Brazil, shows that heat treatment of pea protein and addition of guarana extract result in a compound with significant potential to be used as an ingredient of plan.....»»