Mutations in a non-coding gene associated with intellectual disability
A gene that only makes an RNA is linked to neurodevelopmental problems. Enlarge / The spliceosome is a large complex of proteins and RNAs. (credit: NCBI) Almost 1,500 genes have been implicated in intellectual disabiliti.....»»
Improving transformation frequency in maize
Maize is one of the classical model organisms for genetic research. However, the low transformation frequency remains an important bottleneck for many gene-editing applications......»»
Non-coding RNA acts as "superhighway" for gene expression, study finds
The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins—yet it exists in large quantities......»»
3D maps of diseased tissues at subcellular precision
Researchers in the Systems Biology Lab of Professor Nikolaus Rajewsky, at the Max Delbrück Center, have developed a spatial transcriptomics platform, called Open-ST, that enables scientists to reconstruct gene expression in cells within a tissue in.....»»
Top FDA official overrules staff to approve gene therapy that failed trial
Peter Marks overruled three teams and two top directors. Enlarge / Dr. Peter Marks, Director of the Center for Biologics Evaluation and Research within the Food and Drug Administration on March 18, 2021 in Washington, DC. (credi.....»»
40 years later, X Window System is far more relevant than anyone could guess
One astrophysics professor's memories of writing X11 code in the 1980s. Enlarge (credit: Getty Images) Often times, when I am researching something about computers or coding that has been around a very long while, I will.....»»
Beyond CRISPR: seekRNA delivers a new pathway for accurate gene editing
Scientists at the University of Sydney have developed a gene-editing tool with greater accuracy and flexibility than the industry standard, CRISPR, which has revolutionized genetic engineering in medicine, agriculture and biotechnology......»»
Dietary sucrose determines activity of lithium on gene expression and lifespan in D. melanogaster
The amount of dietary sugars and the administration of lithium both impact the lifespan of the fruit fly Drosophila melanogaster. It is noteworthy that lithium is attributed with insulin-like activity as it stimulates protein kinase B/Akt and suppres.....»»
US bans Kaspersky antivirus software due to national security risks
The US Department of Commerce has announced an upcoming US-wide ban of cybersecurity and antivirus software by Kaspersky, as its “ability to gather valuable US business information, including intellectual property, and to gather US persons’ s.....»»
Wild yeasts from Patagonia could yield new flavors of lagers: Genetic mutations enhance alcohol production
New strains of yeast for brewing lager beers, created by hybridizing wild strains of yeast from Patagonia with brewer's yeast, can yield novel flavors and aromas, reports a new study by Jennifer Molinet and Francisco Cubillos of the Universidad de Sa.....»»
Transcriptomic insights into Chinese cabbage"s unique morphology
Understanding the genetic mechanisms behind leaf development is crucial for improving crop yields and resilience. In Chinese cabbage, the formation of leafy heads involves complex gene interactions that determine leaf shape and orientation. Despite p.....»»
Scientists devise algorithm to engineer improved enzymes
Scientists have prototyped a new method for "rationally engineering" enzymes to deliver improved performance. They have devised an algorithm, which takes into account an enzyme's evolutionary history, to flag where mutations could be introduced with.....»»
Nations realize they need to take risks or lose the race to the moon
The NASA-led Artemis-3 mission will place the first human boots on the surface of the moon since Apollo 17's Gene Cernan and Harrison Schmitt left the lunar surface in December 1972......»»
Lung-targeting lipid nanoparticles with CRISPR components successfully treat cystic fibrosis mouse models
A team of medical researchers from the University of Texas Southwestern Medical Center, Case Western Reserve University School of Medicine and ReCode Therapeutics has developed a way to send gene-editing tools to the lungs to repair the faulty gene a.....»»
How Apple will label AI-generated images made with Image Playground
Apple Intelligence will be used for image generation in iOS 18, and pictures created with Image Playground will be marked. Here's how it's going to work, and what the limitations of the labels are.Image Playground is Apple's new AI-powered image gene.....»»
Tesla sues ex-supplier Matthews over EV battery trade secrets; supplier calls it bullying
Matthews in a statement on Monday said Tesla's lawsuit is "simply a new tactic in their ongoing efforts to bully Matthews and improperly take Matthews' valuable intellectual property.".....»»
Some CRISPR screens may be missing cancer drug targets
CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments, including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow. These genes, or "canc.....»»
Study explores how key gene modulates terpene aroma in grapes
A study explores the ethylene-responsive gene VviERF003's influence on glycosylated monoterpenoid synthesis in grapes, which are pivotal for the fruity and floral notes in wines. Understanding this genetic regulation provides insights into how wine a.....»»
IV infusion enables editing of the cystic fibrosis gene in lung stem cells
Approach relies on lipid capsules like those in the mRNA vaccines. Enlarge (credit: DrAfter123) The development of gene editing tools, which enable the specific targeting and correction of mutations, hold the promise of.....»»
Permanent gene edits to tardigrades help shed light on their amazing resilience
Some species of tardigrades are highly and unusually resilient to various extreme conditions fatal to most other forms of life. The genetic basis for these exceptional abilities remains elusive......»»
Ripe for knowledge: Unraveling the genetic ties of banana softening
A recent study has pinpointed a novel bHLH gene, MabHLH28, as a key regulator of banana fruit ripening. This gene significantly influences the softening process by upregulating the expression of softening-related genes, either independently or in syn.....»»