How Do You Get Drugs to the Brain? Maybe Try a Parasite
A common parasite could one day deliver drugs to the brain. Here's how scientists are turning Toxoplasma gondii from foe into friend......»»
Light-activated polymerization methods unlock new possibilities for intracellular applications
Synthetic polymers play a crucial role in cell biology, serving as delivery vehicles for DNA and drugs, acting as fluorescent probes for cellular sensing, functioning as bioinks for tissue engineering, and mimicking biological functionality (e.g., ar.....»»
New knowledge about cell receptors paves the way for future drugs against intestinal tumors
A new study from Karolinska Institutet published in Nature Communications provides valuable insights into the activation of receptors on the cell surface. The knowledge could lead to new targeted therapies and drugs against intestinal tumors, among o.....»»
Model highlights three roots of online toxicity
In 2022, Professor of Cognitive Neuroscience Dean Mobbs began to investigate the relationship between social media use and mental health and well-being. As his research program ramps up to test brain activity and physiological markers of stress durin.....»»
Mapping the sex life of malaria parasites at single cell resolution reveals genetics underlying transmission
Malaria is caused by a eukaryotic microbe of the Plasmodium genus, and is responsible for more deaths than all other parasitic diseases combined. In order to transmit from the human host to the mosquito vector, the parasite has to differentiate into.....»»
AI tackles one of the most difficult challenges in quantum chemistry
New research using neural networks, a form of brain-inspired AI, proposes a solution to the tough challenge of modeling the states of molecules......»»
With 145 sickened, 2 dead, microdosing candy poisonings are still a mystery
FDA keeps testing—and keeps finding new drugs. But they don't explain the cases. Enlarge (credit: Diamond Shruumz) The number of poisonings connected to Diamond Shruumz-brand microdosing candies has reached 145 cases a.....»»
Novel carbon nanohorn-based treatment enables efficient delivery of drugs in cancer therapy
Cancer remains one of the most challenging diseases to treat due to its complexity and tendency to metastasize (spread into, or invade, nearby tissues or distant places in the body to form new tumors). Traditional therapies, such as chemotherapy and.....»»
Honey bees may play key role in spreading viruses to wild bumble bees
Honey bees may play a role in increasing virus levels in wild bumble bees each spring, according to researchers at Penn State who analyzed seasonal trends of parasite and virus transmission in bees......»»
Roundworm study paves way for better RNA-based drugs to treat human disease
RNA interference (RNAi) therapeutics have garnered significant attention in clinical research due to their potential for treating various diseases, including genetic disorders, viral infections and cancer. These therapeutics can target and silence di.....»»
First spatial map of malaria infection in the liver opens new possibilities for more effective treatments
For the malaria parasite to reach the blood of its human host, it must first enter the liver, where only a small number of parasites differentiate and replicate for upward of seven days, making it a bottleneck in the parasite's lifecycle. This bottle.....»»
This Is the Most Detailed Map of Human Brain Connections Ever Made
In a world first, Harvard biologists worked with Google to diagram a cubic millimeter of human cerebral cortex at the subcellular level, paving the way for the next generation of brain science......»»
Medicare drug price negotiations: 10 list prices drop between 38% to 79%
If the prices were set in 2023, Medicare would have saved $6 billion. Enlarge / Prescription drugs are displayed at NYC Discount Pharmacy in Manhattan on July 23, 2024. (credit: Getty | Spencer Platt) In the first round.....»»
Big-name drugs see price drops in first round of Medicare negotiations
If the prices were set in 2023, Medicare would have saved $6 billion. Enlarge / Prescription drugs are displayed at NYC Discount Pharmacy in Manhattan on July 23, 2024. (credit: Getty | Spencer Platt) In the first round.....»»
Cactus dreams: Revealing the secrets of mescaline making
Mescaline, a natural hallucinogen known since ancient times, was not only a favorite of artists and bohemians but also a mainstay of brain research throughout the first half of the 20th century, until it was eclipsed in the 1950s by the much more pot.....»»
Trojan horse method gives malaria parasites a taste of their own medicine
More than a quarter of Australians over the age of 50 take cholesterol-lowering drugs to prevent heart disease and strokes, but our bodies also need cholesterol to survive. Now, scientists from The Australian National University (ANU) say its role as.....»»
Bumblebees" sense of direction rivals that of humans, study shows
Bumblebees have a great capacity to navigate despite their small brain size. This is borne out of new research conducted at Lund University in Sweden. The research results can potentially benefit the development of navigation robots in crisis situati.....»»
New insights into neural circuit imaging: A comparison of one-photon and two-photon techniques
In the quest to unravel the complexities of neural circuits, scientists are beginning to use genetically encoded voltage indicators (GEVIs) to visualize electrical activity in the brain. These indicators are crucial for understanding how neurons comm.....»»
Supplements Companies Are Cashing In on the Ozempic Wave
With demand for GLP-1 drugs sky-high, the supplement industry is elbowing into the market. Some products are meant to complement meds like Ozempic. Others are positioned as “natural” alternatives......»»
International investigation shuts down Radar/Dispossessor ransomware group
FBI Cleveland announced the disruption of “Radar/Dispossessor”—the criminal ransomware group led by the online moniker “Brain”—and the dismantling of three U.S. servers, three United Kingdom servers, 18 German servers, eight U.....»»
Chemists synthesize plant-derived molecules that hold potential as pharmaceuticals
MIT chemists have developed a new way to synthesize complex molecules that were originally isolated from plants and could hold potential as antibiotics, analgesics, or cancer drugs......»»