How DNA recovered from pill surfaces could snare drug syndicates
Forensic scientists have for the first time shown that DNA can be recovered from the surface of capsules after just 15 seconds of contact by drug manufacturers and dealers—making it possible for law enforcement agencies to track down criminal syndi.....»»
Using AI to find antibodies is fast and produces unimagined molecules
Automation means drug discovery process is less "artisinal" and more streamlined. Enlarge / Researchers use CyBio FeliX workstations to extract and purify DNA samples for testing (credit: LabGenius) At an old biscuit fac.....»»
Glucagon receptor structures uncover new arrestin interaction mechanism
G protein-coupled receptors (GPCRs) are essential for cell signal transduction and constitute the largest drug target protein family. Upon agonist stimulation, these receptors activate multiple downstream transducers, including G proteins and arresti.....»»
Scientists invent new resorbable biomaterials for implantable medical devices
What if we had tiny devices in our bodies that could constantly monitor damaged arteries, accelerate bone regeneration and wound healing, or facilitate drug delivery for cancer treatment? This could open up remarkable opportunities for the treatment.....»»
NASA data shows fierce surface temperatures during Phoenix heat wave
Streets and other built surfaces in the region absorbed and retained heat long after sunset and grew hotter over many days of persistent high temperatures......»»
Scientists study how a diabetes drug affects soils
The transport of pharmaceuticals released from sewage treatment plants into farmland soils, with the potential to load into drinking water sources, is one that researchers at the Illinois Sustainable Technology Center (ISTC) study carefully. Even at.....»»
Nanozymes drive tumor-specific drug delivery while minimizing toxicity
Chemotherapy is a mainstay of cancer treatment. While effective, this therapy indiscriminately kills rapidly dividing cells—cancerous or otherwise—so patients frequently experience severe side effects, ultimately limiting its utility......»»
Carpets found to retain a stubborn grip on pollutants from tobacco smoke
In rooms where smoking has taken place regularly, tobacco's imprint lingers on indoor surfaces, even long after regular smoking has stopped. The leftover residues, known as thirdhand smoke, can be a long-term source of indoor pollutants. New research.....»»
Continuous-flow manufacturing of cefazolin enables more flexible production while reducing cost and waste
The antibiotic cefazolin is an essential drug according to the World Health Organization (WHO). It is usually produced via batch manufacturing. Now for the first-time, researchers have manufactured cefazolin using the continuous-flow method. This me.....»»
The First Pill for Postpartum Depression Is Almost Here
Current treatments for depression after giving birth are either slow to work or hard to get. The FDA is considering a new tablet that relieves symptoms within days......»»
Researchers explore use of AI to improve COVID-19 drug design
Discovering and developing drugs can be slow, costly and high-risk, but harnessing advances in artificial intelligence (AI) can help with these processes, say Brock University researchers......»»
Brazil"s endangered golden monkeys have recovered following big population drop from yellow fever
There are now more golden lion tamarins bounding between branches in the Brazilian rainforest than at any time since efforts to save the species started in the 1970s, a new survey reveals......»»
New drug delivery system containing RNA therapy can target cancer cells in bone marrow
Researchers at Tel Aviv University have destroyed 90% of multiple myeloma blood cancer cells under laboratory conditions, and 60% in human tissues taken from patients at Rabin Medical Center (Belinson Hospital), using an RNA-based drug delivered to t.....»»
To spread or slide? Scientists uncover how foams spread on surfaces
Researchers from Tokyo Metropolitan University have uncovered the physics behind how foams spread on surfaces. The scientists placed balls of foam on a flat substrate and then scraped across it with a plate. They identified different patterns that st.....»»
This Is How the First-Ever U.S. Asteroid Sample Return Will Unfold
Scientists are gearing up for a high-stakes finale to OSIRIS-REx, the first U.S. mission to snare a sample from an asteroid.....»»
Unveiling the 3D structure and molecular mechanism of platelet drug transporter ABCC4
A research team led by Prof. Chen Yuxing and Prof. Zhou Cong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) recently utilized single-particle cryogenic electron microscopy (cryo-EM) to decipher.....»»
A Patient May Be Free of HIV, Thanks to This Drug
Five people went into viral remission after stem cell transplants from donors with HIV resistance. A sixth patient received normal cells. Is an anti-inflammatory drug behind his recovery, instead?.....»»
Breakthrough in solid-state storage innovates how biological materials are stored and handled
Scientists have developed a novel method for storing biological materials such as RNA and proteins in a solid-state. The storage in solid-state resembles the form of a pill or a tablet, which dissolves in water for on-demand use. The innovation provi.....»»
Shedding light on the dark problem of biofilms
Bacterial biofilms are clusters of microorganisms that form on wetted surfaces virtually everywhere. They harbor pathogens that compromise water quality, and they can disrupt the operation of many different engineered systems through the corrosion, f.....»»
Prodrugs: Pills your body converts into an illicit drug can evade detection, but we don"t know how big the problem is
Drug traffickers have found a way to trick enforcement agencies by using one of the most potent tools our bodies have: our metabolism. Welcome to the world of prodrugs......»»
New nanoparticle drug delivery system shows promise in treatment of ectopic pregnancy
Researchers in the Oregon State University College of Pharmacy have developed a drug delivery system that shows promise for greatly enhancing the efficacy of the medicine given to women with the life-threatening condition of ectopic pregnancy, which.....»»