Glucagon receptor structures uncover new arrestin interaction mechanism
G protein-coupled receptors (GPCRs) are essential for cell signal transduction and constitute the largest drug target protein family. Upon agonist stimulation, these receptors activate multiple downstream transducers, including G proteins and arresti.....»»
Researchers identify novel endocytic recycling mechanism with "kiss-and-run" membrane fusion
Endocytosis and recycling control the uptake and retrieval of various materials in eukaryotic cells. Mammalian cells have developed several recycling routes, including the relatively extensively studied "fast" and "slow" tubulovesicular recycling pat.....»»
How a bacterial pathogen that causes dysentery manipulates molecular activity to assure its survival
Virginia Tech researchers have learned how bacteria manipulate molecules to infect the host organism. Daniel Capelluto and his research team have discovered the mechanism by which the bacterial pathogen Shigella flexneri, the causative agent of dysen.....»»
Researchers achieve aluminum molecular ring-based rotaxane and polyrotaxane
Rotaxanes have garnered interest for their unique structures consisting of mechanically interlocked axles and macrocycles. Numerous organic macrocycles have been employed to construct rotaxanes, including crown ether, cyclobis(paraquat-p-phenylene),.....»»
New mechanism uncovered for the reduction of emu wings
.Researchers have uncovered a novel mechanism underlying the skeletal reduction and asymmetry of emu wings. Their research reveals that the absence of distal muscle formation results in a lack of mechanostress during development, leading to the obser.....»»
Webb Telescope provides another look into galactic collisions
An interaction between an elliptical galaxy and a spiral galaxy, collectively known as Arp 107, seems to have given the spiral a happier outlook thanks to the two bright "eyes" and the wide semicircular "smile." The region has been observed before in.....»»
Enhanced ion diffusion kinetics achieved through interpenetrated structures in electrochemical energy storage devices
As global demand for electrochemical electrodes continues to rise, a new trend has emerged, emphasizing the need to maintain ion diffusion efficiency while accommodating ultra-high loadings of active materials to enhance capacity and energy density......»»
Template synthesis creates multilayered perovskites with unique ferroelectric behavior
A group of Nagoya University researchers in Japan has synthesized 4- and 5-layered versions of the important electrical material perovskite. Analyzing the mechanism of ferroelectricity in the material, they found it has a unique function: the materia.....»»
Scientists discover nonstomatal control of water loss in critical crops
Scientists have discovered that certain plants can survive stressful, dry conditions by controlling water loss through their leaves without relying on their usual mechanism—tiny pores known as stomata......»»
Symmetry model sheds light on the chemistry surrounding peptide helices
Helices are structures found naturally in many important molecules, such as proteins. These helices possess a twist that depends on the arrangement of their basic components. By understanding how a helix is formed, we can gain deeper insights into ho.....»»
Gravity study gives insights into hidden features beneath lost ocean of Mars and rising Olympus Mons
Studies of gravity variations at Mars have revealed dense, large-scale structures hidden beneath the sediment layers of a lost ocean. The analysis, which combines models and data from multiple missions, also shows that active processes in the Martian.....»»
Making "atomic lasagna": New method transforms 3D materials into stable layered thin films with promising properties
A research team discovered a method to transform materials with three-dimensional atomic structures into nearly two-dimensional structures—a promising advancement in controlling their properties for chemical, quantum, and semiconducting application.....»»
Dual-feedback mechanism can enhance anti-oxidation coatings in fiber composites
Fiber-reinforced ceramic matrix composites (CMCs) have been the primary choice for radome materials in hypersonic vehicles due to their high toughness, strength, and other advantageous properties. However, oxidation by oxygen in the atmospheric envir.....»»
Researchers aim to control gene expression by studying the memories of cells
Communication between cells is now believed to activate a memory mechanism that sustains gene expression, a finding based on the work of Dr. Gregory Reeves......»»
Discovery about ice layer formation in ice sheets can improve sea level rise predictions
A newly discovered mechanism for the flow and freezing of ice sheet meltwater could improve estimates of sea level rise around the globe......»»
Dru Investigate simplifies cyber investigations and helps users uncover data threats
Druva launched Dru Investigate, a gen AI-powered tool that guides data security investigations using a natural language interface. With Dru Investigate, users across IT, security, legal, and privacy teams can swiftly identify and mitigate data risks,.....»»
Elucidating the mechanism underlying de novo membrane formation during gametogenesis
Researchers at University of Tsukuba have meticulously examined the gametogenesis of budding yeast, a process involving meiosis and spore formation, using live imaging techniques. Their findings reveal that during sporulation, the endoplasmic reticul.....»»
The olive tree"s blueprint: Key insights into high-quality oil production
A pivotal study has decoded the genetic basis of olive oil production, revealing a key regulatory mechanism that shapes oil biosynthesis. By mapping the olive tree's genome and metabolic pathways, researchers have identified how MYC2, a critical tran.....»»
Researchers uncover new infection-fighting molecules through "molecular de-extinction"
A new study led by Cesar de la Fuente, Ph.D., Presidential Assistant Professor of Psychiatry, Microbiology, Chemistry, Chemical and Biomolecular Engineering, and Bioengineering at the University of Pennsylvania, has uncovered sequences for infection-.....»»
Social media interviews uncover New Yorkers" frustrations with high energy costs and reliability
Researchers at Columbia University Mailman School of Public Health are using a novel interview method to assess New Yorkers' perceptions and feelings related to their difficulties paying for and controlling heating and cooling in their homes. Inspire.....»»
Researchers reveal performance boost mechanism in single-atom catalyst for oxygen evolution reaction
Hydrogen energy, with its green, low-carbon and high-calorific-value properties, is emerging as the new key to solving the energy crisis. Electrochemically, water splitting has garnered much attention as a promising hydrogen production technique. How.....»»