How a key immune protein is regulated in the cell
Scientists at EPFL have determined how a protein that is critical in our first line of immune defense is regulated in the cell to prevent autoinflammatory diseases......»»
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Coinfecting viruses obstruct each other"s cell invasion
The process by which phages—viruses that infect and replicate within bacteria—enter cells has been studied for over 50 years. In a new study, researchers from the University of Illinois Urbana-Champaign and Texas A&M University have used cutting-.....»»
The effects of whole genome duplication on the plant metabolome
Whole genome duplication (WGD) is a common mutation in plants with profound evolutionary potential. While it is well-known that an increase in genetic material can lead to larger cell sizes, the impact of gene dosage multiplication on the metabolome.....»»
Scientists "cautiously optimistic" about AI"s role in drug discovery
The human body contains at least 20,000 different proteins, often called the "workhorses of the cell" because of their role in keeping cells healthy. Each protein consists of a unique string of amino acids that affects its shape and function—or dys.....»»
Researchers elucidate mechanisms behind protein selectivity in adenosine receptor
In a new study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out experimental and computational studies to elucidate th.....»»
Climate change may lead to shifts in vital Pacific Arctic fisheries
Marine fisheries are an essential source of protein for a large part of the world's population, as well as supporting around 390 million livelihoods and an industry worth approximately US$ 141 billion, according to the UN FAO. Yet, climate change pre.....»»
Metallic nanosheets curl into nanovesicles
Inspired by the cell membrane structure, researchers, led by Dr. Xiaoqing Huang (State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University) and Dr. Qi Shao (College of Chemistry and.....»»
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Stem cell harmony: How solanaceae plants maintain homeostasis through receptor compensation
A pivotal study sheds light on the evolutionary conservation of stem cell homeostasis in Solanaceae, revealing how receptor compensation mechanisms ensure the continuous and orderly formation of plant organs. This research uncovers the genetic interp.....»»
ACE-ing protein detection in single cells
Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals. This has enabled a much deep.....»»
Dual-action therapy shows promise against aggressive oral cancer
In a new study, scientists at Shanghai Jiaotong University School of Medicine found a promising new way to treat a type of oral cancer known as oral squamous cell carcinoma. The method specifically targets the cancer cells through a combination of ni.....»»
How bacteria attach their cloaks of invisibility to immune defenses
Bacteria have different strategies for protecting themselves. Some bacterial pathogens surround themselves with a shell made of many sugar chains that lie close together, also known as capsular polymers. This protects the bacteria from drying out and.....»»
Precise genetics: New CRISPR method enables efficient DNA modification
With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This targeted cut allows the D.....»»
Highways to health: Bicontinuous structures speed up cell migration
One of the most important but least understood aspects of healing is cell migration, or the process of cells moving from one part of the body to another. "If you are an ambulance out in the woods," says Karen Xu, an M.D/Ph.D. student in Medicine and.....»»
Parasite engineered to deliver therapy proteins to nerve cells
An international team of neurobiologists has developed a way to use a parasite to deliver protein therapies through the blood–brain barrier to treat nerve cell disorders. In their study published in Nature Microbiology, the group engineered the par.....»»
Researchers create a cell atlas of the regenerating liver
The liver has a remarkable ability to regenerate. This property is crucial for maintaining organ function and recovery after injury or surgery. Scientists from the University of Leipzig Medical Center, the Max Planck Institute for Evolutionary Anthro.....»»
Developing new methods for targeted protein degradation
Northwestern Medicine scientists have developed a new, more precise method to target proteins implicated in certain types of cancer, according to a study published in Nature Chemical Biology......»»
Researchers develop a tool for visualizing single-cell data
Modern cutting-edge research generates enormous amounts of data, presenting scientists with the challenge of visualizing and analyzing it. Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the Technical U.....»»
Mass breeding of desert locusts unlocks new food source
Mass breeding of desert locusts in a controlled environment could provide a sustainable source of protein for animals and humans as well as business opportunities in Sub-Saharan Africa, researchers say......»»
Researchers create ADP- or ATP-containing molecules with improved yield and consistency
Adenosine diphosphate (ADP) or adenosine triphosphate (ATP)-containing important biological molecules can modify macromolecules like proteins and nucleic acids to alter their function in the cell. Synthesizing ADP- and ATP-containing molecules using.....»»