How a key immune protein is regulated in the cell
Scientists at EPFL have determined how a protein that is critical in our first line of immune defense is regulated in the cell to prevent autoinflammatory diseases......»»
AI, computation, and the folds of life: Supercomputers help train a software tool for the protein modeling community
Form follows function, and this is especially true for life's building blocks—proteins. The folds and shape of molecular proteins reveal their function in supporting life......»»
Study finds protein reduces toxicity of graphene oxide for drug delivery
A new study has discovered ways to reduce the toxicity of graphene oxide (GO), an ultra-thin sheet of nanomaterial derived from graphite, laying the groundwork to use it as a drug delivery system......»»
Advance in stem cell therapy: New technique for manipulating stem cells opens door to novel treatments
A new technique developed by McGill researchers for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential......»»
International team discovers key protein that helps cells maintain their identity
A discovery regarding Mrc1 (Mediator of Replication Checkpoint 1)—a fission yeast protein involved in DNA replication—has been published in Cell. The discovery is the result of an international research collaboration, led by Professors Genevieve.....»»
Researchers identify body"s "quality control" regulator for protein folding, could lead to targeted treatments
Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-.....»»
Developing a simple, cost-effective method to identify the targets of a crucial protein-modifying enzyme
Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability. Researchers from the Bhogaraju Group at EMBL Grenoble have developed a new method to study a.....»»
Align or die: Revealing unknown mechanism essential for bacterial cell division
A previously unknown mechanism of active matter self-organization essential for bacterial cell division follows the motto "dying to align": Misaligned filaments "die" spontaneously to form a ring structure at the center of the dividing cell. The stud.....»»
A new mechanism for shaping animal tissues
A key question that remains in biology and biophysics is how three-dimensional tissue shapes emerge during animal development. Research teams from the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) in Dresden, Germany, the Exce.....»»
The molecular shield: How tea plants combat drought through protein phosphorylation
Drought stress poses a significant challenge to agriculture, causing substantial yield losses in many crops. Tea plants, known for their rich flavonoid content which enhances both quality and health benefits, are particularly affected. Under drought.....»»
Researchers develop AI model that predicts the accuracy of protein–DNA binding
A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the t.....»»
Largest protein yet discovered builds algal toxins
While seeking to unravel how marine algae create their chemically complex toxins, scientists at UC San Diego's Scripps Institution of Oceanography have discovered the largest protein yet identified in biology......»»
Study reveals how intermittent fasting regulates aging through autophagy
Recent research at the Institute of Molecular Biology and Biotechnology (IMBB) of the Foundation for Research and Technology-Hellas (FORTH), at the Paris Cité University, and at the University of Graz, published today in Nature Cell Biology, sheds l.....»»
Heat stress survival: Unraveling the HsfA2-ACTIN dynamics in lily varieties
A research team has identified that the heat stress transcription factor HsfA2 and actin-interacting protein (AIP) LACTIN interact at the protein level in Lilium longiflorum "White Heaven," mediating gene expression and protecting cells from heat str.....»»
A review of the Epichloë festucae antifungal protein Efe-AfpA
A research team has reviewed the mechanisms behind endophyte-mediated disease resistance in strong creeping red fescue (Festuca rubra subsp. rubra) and identified the antifungal protein Efe-AfpA produced by Epichloë festucae as a key factor against.....»»
Seventh Person ‘Cured’ of HIV after Stem Cell Transplant
A man in Germany is HIV-free after receiving stem cells that are not resistant to the virus.....»»
Fungi adapt cell walls to evade antifungal drugs
Every year, life-threatening invasive fungal infections afflict more than 2 million individuals globally. Mortality rates for these infections are high, even when patients receive treatment......»»
Glimpse into the nanoworld: Microscope reveals tiniest cell processes
What does the inside of a cell really look like? In the past, standard microscopes were limited in how well they could answer this question. Now, researchers from the Universities of Göttingen and Oxford, in collaboration with the University Medical.....»»
How ribosomes in our cells enable protein folding
Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature......»»
Scientists take atomic look at a protein complex that grants access to our DNA
To transcribe the information contained in our genes or to repair the dozens of breaks that occur daily in our DNA, our enzymes must be able to directly access the DNA to perform their functions. However, in the cell nucleus, this access is limited b.....»»
Deals: 14-inch M3 Pro MacBook Pro $300 off, Apple Watch Series 8 GPS + Cell $299 off, Twelve South MacBook stand $40, more
Today’s deals are now ready and waiting down below starting with a new low on Apple’s Space Black $40 low alongside a host of notable deals on charging accessories and more. Head below for a closer look. more….....»»