Glucagon receptor structures uncover new arrestin interaction mechanism
G protein-coupled receptors (GPCRs) are essential for cell signal transduction and constitute the largest drug target protein family. Upon agonist stimulation, these receptors activate multiple downstream transducers, including G proteins and arresti.....»»
New nanocatalyst targets tumors without oxygen
Tumors often contain areas of oxygen-deficient tissue that frequently withstand conventional therapies. This is because the drugs applied in tumors require oxygen to be effective. An international research team has developed a novel mechanism of acti.....»»
Accelerating 3D nanofabrication using a sensitive cationic photoresist
Two-photon laser direct writing lithography or TPL is a cutting-edge technique used for creating nanoscale structures. It works by leveraging specific materials known as photoresists, which change their chemical properties when exposed to light. Thes.....»»
Novel polypeptide-based molecules could pave the way for enhanced polymer design
A research study describes a systematic high-throughput design approach for virtual screening and creation of novel polypeptide-based molecules that form regular secondary structures that can be used in biology or materials science research. The stud.....»»
Quantum simulator could help uncover materials for high-performance electronics
Quantum computers hold the promise to emulate complex materials, helping researchers better understand the physical properties that arise from interacting atoms and electrons. This may one day lead to the discovery or design of better semiconductors,.....»»
Solar-powered animal cells: Combining chloroplasts from algae with hamster cells
Energy-making chloroplasts from algae have been inserted into hamster cells, enabling the cells to photosynthesize light, according to new research in Japan. It was previously thought that combining chloroplasts (chlorophyll containing structures in.....»»
A Lost Mayan City Has Been Found With Laser Mapping
Archaeologists have revealed an ancient lost Mayan city using advanced laser mapping technology, unearthing monumental structures such as pyramids and plazas. Named Valeriana, the city is believed to have been founded before 150 AD......»»
“Impact printing” is a cement-free alternative to 3D-printed structures
Impact printing uses a high-velocity jet of material, fusing it into a structure. Recently, construction company ICON announced that it is close to completing the world’s larges.....»»
Antithrombin study proposes new mechanism of action for the plasma protein"s functional role
Antithrombin, a plasma protein, has been reported to control thrombin activity by directly binding to thrombin, as well as to have an anti-inflammatory effect. However, the actual molecular mechanism of the anti-inflammatory effect of antithrombin wa.....»»
Team observes how iron atoms alter grain boundary structures in titanium
Using state-of-the-art microscopy and simulation techniques, an international research team has systematically observed how iron atoms alter the structure of grain boundaries in titanium. Their findings were published in the journal Science on Octobe.....»»
Scientists uncover key mechanism in pathogen defense, paving way for new antimicrobial strategies
Researchers have made a significant breakthrough in understanding how certain pathogens defend themselves against the host's immune system......»»
Have we found all the major Maya cities? Not even close, new research suggests
Archaeologists have analyzed lidar data from a completely unstudied corner of the Maya world in Campeche, Mexico, revealing 6,674 undiscovered Maya structures, including pyramids like those at the famous sites of Chichén Itzá or Tikal......»»
Protecting endangered bats with biomaterials
Oak Ridge National Laboratory researchers are using a new bioderived material to 3D print custom roosting structures for endangered bats......»»
Pompeii archaeologists uncover ancient tiny house with elaborate frescoes
Pompeii archaeologists uncover ancient tiny house with elaborate frescoes.....»»
Experts uncover stunning side effects of solar farms: "Introducing structural complexity into the environment"
Experts uncover stunning side effects of solar farms: "Introducing structural complexity into the environment".....»»
From fireflies to drones: Researchers uncover strategy for synchronization efficiency
Researchers from The University of New Mexico School of Engineering looked to the natural world to explain how synchronized systems can work more efficiently and made a significant discovery. Their results were published in the journal Nature Communi.....»»
Microbes feed on iron: New study reveals how they do it
Pipelines, sprinklers, and other infrastructure in oxygen-free environments are vulnerable to microbially induced corrosion (MIC)—a process where microorganisms degrade iron-based structures, potentially leading to costly damages or even collapses......»»
Scientists uncover how transcription drives motion within the genome
A team of scientists has discovered surprising connections among gene activity, genome packing, and genome-wide motions, revealing aspects of the genome's organization that directly affect gene regulation and expression......»»
"Making insurance effective in the face of climate change may require it to be legally enforced"
Recent hurricanes hitting the Southeastern United States have again robbed people of their homes, businesses and lives. Hurricane Helen, in late September, was followed up last week by Hurricane Milton, collapsing seemingly robust building structures.....»»
How plants compete for light: Researchers discover new mechanism in shade avoidance
Plants that are close together do everything they can to intercept light. This "shade avoidance" response has been extensively researched. It is therefore even more remarkable that researchers from the laboratory of Molecular Biology at Wageningen Un.....»»
Tracking vampire worms with machine learning
Blood samples of patients infected with a parasitic worm that causes schistosomiasis contain hidden information that marks different stages of the disease. In our recently published research, our team used machine learning to uncover that hidden info.....»»