Glucagon receptor structures uncover new arrestin interaction mechanism
G protein-coupled receptors (GPCRs) are essential for cell signal transduction and constitute the largest drug target protein family. Upon agonist stimulation, these receptors activate multiple downstream transducers, including G proteins and arresti.....»»
Tracking vampire worms with machine learning
Blood samples of patients infected with a parasitic worm that causes schistosomiasis contain hidden information that marks different stages of the disease. In our recently published research, our team used machine learning to uncover that hidden info.....»»
3D structures of biomolecules: "Dictionaries" make fluorescence-based data accessible
A research team from Germany and the U.S. led by Heinrich Heine University Düsseldorf (HHU) has developed a data description that can provide results from fluorescence measurements for structural and dynamic modeling of large biomolecules......»»
Physicists uncover universal non-equilibrium quantum dynamics in randomly interacting spin models
A new study has uncovered the universal dynamics far from equilibrium in randomly interacting spin models, thereby complementing the well-established universality in low-energy equilibrium physics. The study, recently published in Nature Physics, was.....»»
Integrated space-ground technologies empower archaeological research into ancient tombs
A team of international researchers has employed an integrated approach to uncover the mysteries of the Eastern Mausoleum of Qin State, an ancient royal burial site from China's Warring States period......»»
Butterfly brains reveal the tweaks required for cognitive innovation
A species of tropical butterfly with unusually expanded brain structures displays a fascinating mosaic pattern of neural expansion linked to a cognitive innovation......»»
Abiotic organic synthesis research proposes new mechanism for organic condensation
A Chinese research team has reported the discovery of abiotic organic compounds in the oceanic crust of the Southwest Indian Ridge and proposed a molecular mechanism for organic condensation......»»
Cryo-electron microscopy sheds light on endothelin signaling mechanisms
Endothelin is a peptide hormone known for its vasoconstrictive effects. Researchers at University of Tsukuba used cryo-electron microscopy to examine the complex structure of the endothelin receptor and G protein, which are crucial for signal transdu.....»»
Mechanism of cobalt–manganese catalysts deciphered
Conventional catalysts for hydrogen production via water electrolysis usually contain precious metals and are expensive. However, cheaper alternatives have been developed, for example cobalt–manganese catalysts. They have a high activity and are st.....»»
Janus-like metasurface technology shows different optical responses according to the direction of light
Metasurface technology is an advanced optical technology that is thinner, lighter, and more capable of precisely controlling light through nanometer-sized artificial structures than conventional technologies. KAIST researchers have overcome the limit.....»»
Microtubule formation mechanism sheds light on how cells build their internal skeleton
Inside every cell, a network of tiny filaments, called the microtubule cytoskeleton, helps maintain the cell's shape, allows it to divide, and transports vital materials from one part of the cell to another. The filaments that form this network, term.....»»
First coherent picture of an atomic nucleus made of quarks and gluons
The atomic nucleus is made up of protons and neutrons, particles that exist through the interaction of quarks bonded by gluons. It would seem, therefore, that it should not be difficult to reproduce all the properties of atomic nuclei hitherto observ.....»»
Scientists apply ancient construction methods to help fabricate modern microparticles
Inspired by the ancient East Asian method of constructing wooden structures using a "tongue and groove" technique, Nanyang Technological University, Singapore (NTU Singapore) scientists have developed a new approach to fabricating advanced ceramic mi.....»»
Digital quantum simulation of nuclear magnetic resonance experiments
Programmable quantum computers have the potential to efficiently simulate increasingly complex molecular structures, electronic structures, chemical reactions, and quantum mechanical states in chemistry that classical computers cannot. As the molecul.....»»
Physicists uncover behavior in quantum superconductors that provides a new level of control
A new study has uncovered important behavior in the flow of electric current through quantum superconductors, potentially advancing the development of future technologies like quantum computing......»»
Can walls of oysters protect shores against hurricanes? Darpa wants to know.
Colonized artificial reef structures could absorb the power of storms. On October 10, 2018, Tyndall Air Force Base on the Gulf of Mexico—a pillar of American air superiority—f.....»»
Researchers uncover role of plasma waves in mysterious heating of sun"s corona
There is a profound mystery in our sun. While the sun's surface temperature measures around 10,000 degrees Fahrenheit, its outer atmosphere, known as the solar corona, measures more like 2 million degrees Fahrenheit, about 200 times hotter......»»
Researchers create a three-dimensional multi-focus laser for glass micro-sculpting
Glass materials are widely used in optical and optoelectronic devices due to their low cost and excellent mechanical and optical properties. Among them, glass concave/convex linear structures with feature sizes ranging from several micrometers to hun.....»»
Darpa Thinks Walls of Oysters Could Protect Shores Against Hurricanes
The US defense research agency is funding three universities to engineer reef structures that will be colonized by corals and bivalves and absorb the power of future storms......»»
Study unveils cobalt(III) reaction mechanism with nitriles, opening pathways for drug development
A research team led by Professor Jaeheung Cho from the Department of Chemistry at UNIST has published a study in the Journal of the American Chemical Society reporting the reaction mechanism of cobalt(III)-based metal complexes with nitrile substance.....»»
Plant stem cells: Understanding the biological mechanism of growth control
Researchers from the University of Freiburg have identified the HAN molecule as an important regulator that controls plant growth in conjunction with WOX5. Understanding this mechanism is relevant for breeding more resilient or higher-yielding crops......»»