Getting protein factories to run—How deubiquitinating enzymes moonlight as Fubi proteases
The small protein ubiquitin is particularly famous for marking proteins for degradation but it has also been shown to regulate virtually all cellular processes. In parallel to the ubiquitin system various other ubiquitin-like modifiers have evolved,.....»»
New process uses light and enzymes to create greener chemicals
Researchers at the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) have achieved a significant breakthrough that could lead to better—and greener—agricultural chemicals and everyday products......»»
China poised to lead global auto market, S&P Global says
BYD has emerged as a top 10 manufacturer, and evolving retail networks and new factories in Europe offer opportunities for Chinese automakers. Despite European and North American tariffs, they continue to push forward......»»
Cheesemaking is a complex science—a food chemist explains the process from milk to mozzarella
Cheese is a relatively simple food. It's made with milk, enzymes—these are proteins that can chop up other proteins—bacterial cultures and salt. Lots of complex chemistry goes into the cheesemaking process, which can determine whether the cheese.....»»
Smart guide RNAs: Researchers use logic gate-based decision-making to construct circuits that control genes
Researchers have transformed guide RNAs, which direct enzymes, into a smart RNA capable of controlling networks in response to various signals. A research team consisting of Professor Jongmin Kim and Ph.D. candidates Hansol Kang and Dongwon Park fro.....»»
Nanoscopic imaging aids in understanding protein, tissue preservation in ancient bones
A pilot study from North Carolina State University shows that nanoscopic 3D imaging of ancient bone not only provides further insight into the changes soft tissues undergo during fossilization, it also has potential as a fast, practical way to determ.....»»
Study deciphers intricate 3D structure of DNA aptamer for disease theranostics
In a study published in PNAS, a research team has resolved the first high-resolution structure of the sgc8c DNA aptamer that targets protein tyrosine kinase 7 (PTK7), engineered two optimal sgc8c variants for disease theranostics efficiently, and rev.....»»
Discovery of a tRNA modification enzyme that also acts on nucleosides
The genetic information on DNA is transcribed into messenger RNA (mRNA) and translated to the amino acid sequence by transfer RNA (tRNA) on the ribosome. Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis.....»»
Nano-scale materials that mimic enzymes could convert CO₂ into chemical building blocks
Montana State University researcher James Crawford recently published a collaborative paper with the National Renewable Energy Laboratory that marks a step forward in their quest for what he calls a "holy grail" of chemistry: converting the greenhous.....»»
Modular design: New insights into protein factories in human mitochondria
The "power plants" of living cells, the mitochondria, probably evolved through endosymbiosis: A bacterium migrated into a primordial cell and eventually developed into an organelle that provides the cell with energy, among other things. Mitochondria.....»»
Scientists develop dual-functional, high-efficiency antimicrobial nanozyme
A research team led by Prof. Gao Lizeng from the Institute of Biophysics of the Chinese Academy of Sciences proposed a bactericidal mechanism based on nanozymes that simulate antimicrobial peptides (AMPs) and antimicrobial enzymes (AMEs) according to.....»»
Snakes on a plate: Pythons touted as protein alternative
In a warehouse in the lush humid farmlands of central Thailand, thousands of pythons lie coiled in containers, rearing and striking at the glass as people pass by......»»
Lab develops smallest free-floating bubbles for medical imaging
Bioengineering researchers at Rice University have developed ultrasmall, stable gas-filled protein nanostructures that could revolutionize ultrasound imaging and drug delivery......»»
Novel protein found to inhibit activity of CRISPR-Cas system
In a study published in Nature on July 3, researchers from the Institute of Biophysics of the Chinese Academy of Sciences and the University of Toronto, Canada, discovered a novel anti-CRISPR protein called AcrIF25, which inhibits the activity of the.....»»
Opening the right doors: New work reveals "jumping gene" control mechanisms
International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents t.....»»
Team investigates chemical modifications to gain deeper insights into genetic regulation mechanisms
University of North Carolina at Chapel Hill researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation, according to the paper, "Drosophila.....»»
Unexpected phage protein function discovered in bacteria battle
An unexpected find has enabled important progress to be made in the battle against harmful bacteria. An international team of researchers, led by Professor Peter Fineran from the University of Otago, investigated a particular protein used by bacteria.....»»
Intracellular mechanisms shown to promote spread of deadly bacterial infection
Northwestern Medicine investigators have discovered novel protein mechanisms that promote the rapid spread of Vibrio vulnificus, a rare but lethal bacteria that can cause vibriosis and sepsis, according to findings published in the Proceedings of the.....»»
New method enables amplifiable protein identification from trace samples
In a study published in the journal National Science Review, researchers developed an amplifiable protein identification method called "AmproCode.".....»»
Innovative use of hyperspectral data and DCGANs enhances rice protein content estimation
Rice (Oryza sativa L.) is a crucial crop feeding over half of the global population. The demand for high-quality, protein-rich rice is rising, making accurate grain protein content (GPC) estimation vital for breeding superior varieties......»»
Novel protein involved in mitochondrial gene expression identified
Researchers at the Department of Medical Biochemistry and Biophysics at Karolinska Institutet have characterized a novel GTPase involved in ribosome production in mitochondria. The study, published in Nature Communications, provides new insights into.....»»