Genome of Steller"s sea cow decoded
During the Ice Age, giant mammals such as mammoths, saber-toothed cats and wooly rhinoceroses once roamed Northern Europe and America. The cold oceans of the northern hemisphere were also home to giants like Steller's sea cow, which grew up to eight.....»»
The "unknome": A database of human genes we know almost nothing about
Researchers from the United Kingdom hope that a new, publicly available database they have created will shrink, not grow, over time. That's because it is a compendium of the thousands of understudied proteins encoded by genes in the human genome, who.....»»
Size matters: Genome size dynamics driven by copy number variation in a green alga
A new study challenges the conventional wisdom surrounding genome stability within closely related organisms and sheds new light on the mechanisms underlying extensive genome size variation......»»
Your Genes May Influence What You Like to Eat
New research identifies genome areas linked to dietary patterns and our taste for things such as tea, tobacco and grapes.....»»
Genome data rewrite the story of oat domestication in China
Oat is among the top ten cereal crop species in terms of global production. It can adapt to different climates, and farmers can grow it successfully even in harsh environments where other crops such as rice and corn fail. However, not all oat plants.....»»
Genome analysis of 46,000-year-old roundworm from Siberian permafrost reveals novel species
Some organisms, such as tardigrades, rotifers, and nematodes, can survive harsh conditions by entering a dormant state known as "cryptobiosis.".....»»
Generation of a human haploid neural stem cell line for genome-wide genetic screening
Haploid embryonic stem cells (haESCs) have been established in many species. Differentiated haploid cell line types in mammals are lacking due to spontaneous diploidization during differentiation that compromises lineage-specific screens......»»
Modifying shelf-life of melons via gene editing
The gaseous plant hormone ethylene has been long known to promote fruit ripening and plays a certain role in shelf-life. In a study published in Frontiers in Genome Editing, researchers performed gene editing using the Clustered Regularly Interspaced.....»»
SeqCode provides a path to name uncultivated prokaryotes
Most prokaryotes have never been isolated in pure culture and cannot be named under the International Code of Nomenclature of Prokaryotes (ICNP). However, many studies have described uncultured bacteria and archaea though metagenome-assembled genome.....»»
Bacterial single-cell, whole-genome sequencing overhauled by engineered polymerase
Sequencing the genome of single bacterial cells has long been technically difficult due to the seemingly unalterable bias in the gene amplification stage of the process, making it hard to produce high-coverage genome sequence from precisely just one.....»»
Spiritual people more likely to be skeptical about science, study finds
Scientists surveyed 600 Dutch people on what they think and believe about certain topics and how that affects their opinions on science. Specifically, it involved what they thought about nanotechnology, human genome editing and artificial intelligenc.....»»
Ancient "Unknown" Script Is Finally Deciphered
Researchers have decoded more than half of the characters in the so-called Kushan script by comparing them with inscriptions in a known ancient language called Bactrian.....»»
Scientists create high-quality chromosome-level reference genome of Chelidonichthys spinosus
Chelidonichthys spinosus, commonly known as the spiny red gurnard in the order Scorpaeniformes, is a typical migratory fish that undertakes offshore overwintering migrations in late autumn and early winter, and returns to nearshore areas for spawning.....»»
App for visualizing the bovine physical–genetic map
Physical maps are created in genome research to illustrate how the genetic information is arranged on individual chromosomes. In addition, genetic maps show the probability with which genetic variants can be transmitted together from one parent to an.....»»
An Ancient Battle Is Playing Out in the DNA of Every Embryo
Millions of years ago, retroviruses invaded the human genome. Today some of these viral remnants threaten the developing embryo, while others fight to defend it......»»
Researchers decode the structure of a crucial neural transport protein
Using Cryo-EM, a powerful microscopy technique, researchers at the Indian Institute of Science (IISc) and collaborators have decoded the molecular architecture of a transporter protein controlling the movement of a key neurotransmitter. Their work is.....»»
Supersize the cell: Unlocking genome secrets through expansion microscopy
The ability to turn genes on or off is fundamental to the diversity we see in cells, in individuals, and even in terms of health and disease. This process, known as gene transcription, involves converting the information stored in our DNA into a "car.....»»
Transplantation of genome-edited iPS cells delivers therapeutic molecules in vivo
Induced pluripotent stem (iPS) cells have a great impact on biology and medicine, and they are expected to improve regenerative medicine. Since 2014, when a sheet of retinal pigment epithelial cells derived from iPS cells was transplanted into patien.....»»
Zeroing in on the workings of tumor suppressor protein p53, the "guardian of the genome"
The tumor suppressor protein p53 has been dubbed the "guardian of the genome" because it protects the DNA from stress or long-term damage by regulating the expression of numerous genes involved DNA repair, cell division and cell death. Now, FMI resea.....»»
New platform slashes time to engineer and select the best genome editors for specific applications
A research team from the LKS Faculty of Medicine, the University of Hong Kong (HKUMed) has developed a new way to break through the current limited throughput in optimizing precise genome editors at scale, and engineer hundreds (or more) of base edit.....»»
Researchers provide first chromosome-level genome assembly in Murraya plants
Murraya paniculata, commonly known as orange jessamine in the family Rutaceae, is an important ornamental plant in tropical and subtropical regions that is famous for its strong fragrance. As an ornamental plant with strong flower aroma, the floral v.....»»