Freeze! Executioner protein caught in the act
A new molecular 'freeze frame' technique has allowed WEHI researchers to see key steps in how the protein MLKL kills cells......»»
Study finds protein reduces toxicity of graphene oxide for drug delivery
A new study has discovered ways to reduce the toxicity of graphene oxide (GO), an ultra-thin sheet of nanomaterial derived from graphite, laying the groundwork to use it as a drug delivery system......»»
International team discovers key protein that helps cells maintain their identity
A discovery regarding Mrc1 (Mediator of Replication Checkpoint 1)—a fission yeast protein involved in DNA replication—has been published in Cell. The discovery is the result of an international research collaboration, led by Professors Genevieve.....»»
Researchers identify body"s "quality control" regulator for protein folding, could lead to targeted treatments
Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-.....»»
Developing a simple, cost-effective method to identify the targets of a crucial protein-modifying enzyme
Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability. Researchers from the Bhogaraju Group at EMBL Grenoble have developed a new method to study a.....»»
The molecular shield: How tea plants combat drought through protein phosphorylation
Drought stress poses a significant challenge to agriculture, causing substantial yield losses in many crops. Tea plants, known for their rich flavonoid content which enhances both quality and health benefits, are particularly affected. Under drought.....»»
Researchers develop AI model that predicts the accuracy of protein–DNA binding
A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the t.....»»
Largest protein yet discovered builds algal toxins
While seeking to unravel how marine algae create their chemically complex toxins, scientists at UC San Diego's Scripps Institution of Oceanography have discovered the largest protein yet identified in biology......»»
Heat stress survival: Unraveling the HsfA2-ACTIN dynamics in lily varieties
A research team has identified that the heat stress transcription factor HsfA2 and actin-interacting protein (AIP) LACTIN interact at the protein level in Lilium longiflorum "White Heaven," mediating gene expression and protecting cells from heat str.....»»
A review of the Epichloë festucae antifungal protein Efe-AfpA
A research team has reviewed the mechanisms behind endophyte-mediated disease resistance in strong creeping red fescue (Festuca rubra subsp. rubra) and identified the antifungal protein Efe-AfpA produced by Epichloë festucae as a key factor against.....»»
How ribosomes in our cells enable protein folding
Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature......»»
Scientists take atomic look at a protein complex that grants access to our DNA
To transcribe the information contained in our genes or to repair the dozens of breaks that occur daily in our DNA, our enzymes must be able to directly access the DNA to perform their functions. However, in the cell nucleus, this access is limited b.....»»
Nvidia reportedly caught scraping AI data from Netflix and YouTube (again)
Nvidia helped itself to "a human lifetime visual experience worth of training data per day," according to company execs......»»
Scientists "cautiously optimistic" about AI"s role in drug discovery
The human body contains at least 20,000 different proteins, often called the "workhorses of the cell" because of their role in keeping cells healthy. Each protein consists of a unique string of amino acids that affects its shape and function—or dys.....»»
Researchers elucidate mechanisms behind protein selectivity in adenosine receptor
In a new study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out experimental and computational studies to elucidate th.....»»
Astronomers use AI to find elusive stars "gobbling up" planets
Astronomers have recently found hundreds of "polluted" white dwarf stars in our home galaxy, the Milky Way. These are white dwarfs caught actively consuming planets in their orbit. They are a valuable resource for studying the interiors of these dist.....»»
Climate change may lead to shifts in vital Pacific Arctic fisheries
Marine fisheries are an essential source of protein for a large part of the world's population, as well as supporting around 390 million livelihoods and an industry worth approximately US$ 141 billion, according to the UN FAO. Yet, climate change pre.....»»
Report: Apple disrupts overseas acquisition that involves Indian partner
Apple is a technology company. It specializes in creating products. But as a global force in the world, it can also get caught up in international drama. Today, a new report details one such situation playing out that involves India, China, and compe.....»»
ACE-ing protein detection in single cells
Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals. This has enabled a much deep.....»»
Precise genetics: New CRISPR method enables efficient DNA modification
With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This targeted cut allows the D.....»»
Parasite engineered to deliver therapy proteins to nerve cells
An international team of neurobiologists has developed a way to use a parasite to deliver protein therapies through the blood–brain barrier to treat nerve cell disorders. In their study published in Nature Microbiology, the group engineered the par.....»»