Establishing the basis for mammalian intracellular computing with mRNA switches
Professor Hirohide Saito and his research team have developed a new approach to control mRNA translation using Cas proteins, thus expanding the variety of mRNA switches and making it easier to build synthetic gene circuits in mammalian cells. The res.....»»
Structural and biochemical basis of methylmalonate semialdehyde dehydrogenase ALDH6A1
ALDH6A1, a member of the ALDH family, plays a crucial role in the catabolic pathways of valine and thymine. Dysregulation of ALDH6A1 expression has been linked to a variety of diseases. Methylmalonate semialdehyde dehydrogenase deficiency (MMSDH defi.....»»
Gene editing technology reveals molecular mechanisms governing diatom population density signals
The intricate dynamics of diatom blooms, influenced by a myriad of external factors and internal signals, continue to fascinate scientists. After recognizing the potential role of density perception and intracellular signaling in dictating these phen.....»»
Researchers reveal impact of brassinosteroid and sugar signal on wheat grain size regulation
Grain size plays a central role in determining wheat yield, and precise regulation of grain development has emerged as a key strategy for increasing yields in several staple crops such as rice and maize. However, the genetic basis and potential molec.....»»
8BitDo’s $100 wireless mechanical keyboard is a tribute to Commodore 64
The clicky Kailh White switches are easily replaceable. Fits in nicely with old cassettes and floppy disks. [credit: 8Bi.....»»
Quantum computing just got hotter: One degree above absolute zero
For decades, the pursuit of quantum computing has struggled with the need for extremely low temperatures, mere fractions of a degree above absolute zero (0 Kelvin or –273.15°C). That's because the quantum phenomena that grant quantum computers the.....»»
Chemists develop method to confirm mRNA vaccine stability
University at Albany researchers at the RNA Institute have developed a new method to test COVID-19 vaccine integrity that could allow anyone with basic skills in vaccine handling to detect expired vaccines quickly and effectively, without specialized.....»»
Quantum computing progress: Higher temps, better error correction
Amazon, IBM, and traditional silicon makers all working toward error correction. Enlarge (credit: vital) There's a strong consensus that tackling most useful problems with a quantum computer will require that the compute.....»»
Unlocking quantum computing power: Automated protocol design for quantum advantage
Imagine a world where complex calculations that currently take months for our best supercomputers to crack could be performed in a matter of minutes. Quantum computing is revolutionizing our digital world. In a research article published in Intellige.....»»
Does Apple"s platform need to be opened up?
Does the European Union, the United States, or other governments need to intervene to fix potential problems in competitive markets for personal computing?Apple has a monopoly on the Steve Jobs TheaterApple's App Store, iPhone and its services includ.....»»
Celebrate modern computing and technology with Dell’s Techfest deals
It's time to celebrate modern technology and computing with Dell's Techfest deals, a selection of discounts on powerful gear......»»
The world is one step closer to secure quantum communication on a global scale
Researchers at the University of Waterloo's Institute for Quantum Computing (IQC) have brought together two Nobel prize-winning research concepts to advance the field of quantum communication......»»
Can mRNA vaccines help boost livestock production?
University of Queensland researchers say mRNA vaccine technology could play an important role in boosting livestock production to meet global food demands......»»
Messenger RNAs with multiple "tails" could lead to more effective therapeutics, say researchers
Messenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines. But mRNAs, which are genetic sequences that instruct the body to produce proteins, are also being devel.....»»
Research seeks to develop mRNA lipid nanoparticles for next-generation oral cancer tumor suppressor therapy
A study aiming to develop a lipid nanoparticles (LNP) platform for treating oral squamous cell carcinoma (OSCC) utilizing p53 mRNA was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of t.....»»
Kasada introduces CDN edge API integrations to block abuse and online fraud
Kasada released a bot detection API with out-of-the-box integrations for Content Delivery Network (CDN) edge computing platforms. Security teams can use the new integrations to quickly block abuse and online fraud without sacrificing user experience.....»»
Genetic basis for the evolution of hair discovered in the clawed frog
The development of hair was of central importance for the evolution of mammals and, thus, also of humans. However, the evolutionary origin of the genetic program of hair was previously unknown. An international research team led by Leopold Eckhart fr.....»»
Elegant use of noise for quantum computing
Scientists around the world work hard to rinse quantum systems for noise, which may disturb the function of tomorrow's powerful quantum computers. Researchers from the Niels Bohr Institute (NBI) have found a way to use noise to process quantum inform.....»»
GM puts 2 newcomers in pivotal roles
General Motors hired Jens Peter Clausen, formerly of Tesla, to lead global manufacturing, while Baris Cetinok, who has worked at Apple and Microsoft, will lead its software and services team on an interim basis......»»
Keychron Q1 Max review: cushy, comfortable, costly
The Keychron Q1 Max is a 75% mechanical keyboard filled to the brim with foam with a smooth typing experience, featuring exclusive — and pricey — Gateron Jupiter switches and a 1,000 Hz polling rate.Keychron Q1 Max reviewKeychron is not slowing d.....»»
Exploring the transferability of extracytoplasmic function switches across bacterial species
Extracytoplasmic function sigma factors (ECFs) have been successfully used for constructing predictable artificial gene circuits in bacteria like Escherichia coli, but their transferability between species within the same phylum remained unknown......»»