Observing mammalian cells with superfast soft X-rays
Researchers have developed a new technique to view living mammalian cells. The team used a powerful laser, called a soft X-ray free electron laser, to emit ultrafast pulses of illumination at the speed of femtoseconds, or quadrillionths of a second......»»
Decoding reactive species in molten salts
By unraveling vibrational signatures and observing ion exchanges, an Oak Ridge National Laboratory team revealed how chemical species form in a highly reactive molten salt mixture of aluminum chloride and potassium chloride. The findings are publishe.....»»
IV infusion enables editing of the cystic fibrosis gene in lung stem cells
Approach relies on lipid capsules like those in the mRNA vaccines. Enlarge (credit: DrAfter123) The development of gene editing tools, which enable the specific targeting and correction of mutations, hold the promise of.....»»
Advances in techniques used to identify sharks and rays is not preventing trade and increase in extinction risk: Study
The most advanced molecular techniques contribute significantly to the identification of endangered sharks, rays and skates, collectively known as elasmobranchs, and are therefore fundamental to the enforcement of the laws and regulations governing t.....»»
Not wrapping but folding: Bacteria also organize their DNA, but they do it a bit differently
Some bacteria, it turns out, have proteins much like ours that organize the DNA in their cells. They just do it a bit differently. This is revealed by new research from biochemists at the Leiden Institute of Chemistry and the Max Planck Institute for.....»»
Nanowires create elite warriors to enhance T cell therapy
Adoptive T-cell therapy has revolutionized medicine. A patient's T-cells—a type of white blood cell that is part of the body's immune system—are extracted and modified in a lab and then infused back into the body, to seek and destroy infection, o.....»»
"Synthetic" cell shown to follow chemical directions and change shape, a vital biological function
In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a govern.....»»
UAW, Ultium Cells reach tentative agreement
The UAW and Ultium Cells have come to a tentative agreement on improvements in wages, health and safety measures after 18 months of negotiation. The agreement serves as a local supplement to the bigger master contract of the Detroit 3......»»
"Smart" chemistry allows recycling of networked rubbery materials
Oak Ridge National Laboratory scientists ingeniously created a sustainable, soft material by combining rubber with woody reinforcements and incorporating "smart" linkages between the components that unlock on demand. The smart linkages allow heat to.....»»
Lung organoids reveal how pathogens infect human lung tissue
How do pathogens invade the lungs? Using human lung microtissues, a team at the Biozentrum of the University of Basel has uncovered the strategy used by a dangerous pathogen. The bacterium targets specific lung cells and has developed a sophisticated.....»»
Deriving mammalian DNA methylation predictors for maximum life span, gestation time and age at sexual maturity
A research team has found that there are epigenetic predictors of species life span and other traits in mammals. In their paper published in the journal Science Advances, the group describes how they analyzed data held in a database created by the Ma.....»»
Spliceosomes: New technique tracks proteins involved in RNA splicing
Bodybuilders and cellular mechanisms agree generating protein is a heavy lift. To complete the task, cells rely on complexes called spliceosomes. These molecular machines snip extra bits out of our genes' RNA copies and piece together precise instruc.....»»
Improved prime editing system makes gene-sized edits in human cells at therapeutic levels
Scientists at the Broad Institute of MIT and Harvard have improved a gene-editing technology that is now capable of inserting or substituting entire genes in the genome in human cells efficiently enough to be potentially useful for therapeutic applic.....»»
Dead Cells designer’s new game, Tenjutsu, is a yakuza action roguelike
Devolver Digital will publish Tenjutsu, the next game from Dead Cells creator Sébastien Benard......»»
QUIET: A place to study qubits shielded from the effects of cosmic rays
Deep under the ground at Fermi National Accelerator Laboratory is a brand-new quantum sensor and computing research center called QUIET, and at the surface—100 meters above—sits its twin called LOUD......»»
Potential drug targets identified in African swine fever virus enzyme study
African swine fever virus is the only mammalian infectious virus that encodes type II DNA topoisomerase and has caused serious damage to the global swine industry in recent years. Safe and effective commercial vaccines and drugs are still lacking......»»
Marsupials key to discovering the origin of heater organs in mammals
Around 100 million years ago, a remarkable evolutionary shift allowed placental mammals to diversify and conquer many cold regions of our planet. New research from Stockholm University shows that the typical mammalian heater organ, brown fat, evolved.....»»
A novel spray device helps researchers capture fast-moving cell processes
Cells are the basic units of life—but many of their fundamental processes happen so fast and at such small length scales that current scientific tools and methods can't keep up, preventing us from developing a deeper understanding......»»
How a protein component of nuclear pore complexes regulates development of blood cells, contributes to myeloid disorders
Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin organization and RNA processes that influence cel.....»»
Study links nanoparticles to altered blood vessel formation in embryos
Human life begins with a single egg cell that grows into a human being with trillions of cells. To ensure that the highly complex development of tissues and organs is as protected as possible, the placental barrier keeps pathogens and foreign substan.....»»
Q&A: Studies reveal gut"s true stem cells, challenging previous assumptions
Two independent studies by Columbia scientists suggest that research into the gut's stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell......»»