Epigenetic regulator explains why some lung cancer patients become resistant to common therapeutics
Cellular biologists discover why some patients become resistant to standard treatments for nonsmall cell lung cancer......»»
Study sheds light on cancer cell "tug-of-war"
Understanding how cancerous cells spread from a primary tumor is important for any number of reasons, including determining the aggressiveness of the disease itself. The movement of cells into the extracellular matrix (ECM) of neighboring tissue is a.....»»
Nanoparticle researchers develop microfluidic platform for better delivery of gene therapy for lung disease
Drug delivery researchers at Oregon State University have developed a device with the potential to improve gene therapy for patients with inherited lung diseases such as cystic fibrosis......»»
Laboratory and natural strains of intestinal bacterium turn out to have similar mutational profiles
Understanding mutational processes in a cell offers clues to the evolution of a genome. Most actively, mutation processes are studied in human cancer cells, while other genomes are often neglected......»»
Dogma-challenging telomere findings may offer new insights for cancer treatments
A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of chromosomes, and that impairing this process can.....»»
Geologists, biologists unearth the atomic fingerprints of cancer
Scientists at the University of Colorado Boulder and Princeton University have, for the first time, employed a tool often used in geology to detect the atomic fingerprints of cancer......»»
Researchers develop a nanoparticle that can penetrate the blood-brain barrier
Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have developed a nanoparticle that can penetrate the blood-brain barrier. Their goal is to kill primary breast cancer tumors and brain metastase.....»»
Simulated chemistry: New AI platform designs tomorrow"s cancer drugs
Scientists at UC San Diego have developed a machine learning algorithm to simulate the time-consuming chemistry involved in the earliest phases of drug discovery, which could significantly streamline the process and open doors for never-before-seen t.....»»
Hungry, hungry white dwarfs: Solving the puzzle of stellar metal pollution
Dead stars known as white dwarfs, have a mass like the sun while being similar in size to Earth. They are common in our galaxy, as 97% of stars are white dwarfs. As stars reach the end of their lives, their cores collapse into the dense ball of a whi.....»»
Lake tsunamis pose significant threat under warming climate
Cowee Creek, Brabazon Range, Upper Pederson Lagoon—they mark the sites of recent lake tsunamis, a phenomenon that is increasingly common in Alaska, British Columbia and other regions with mountain glaciers......»»
Novel triple drug combination effective against antibiotic-resistant bacteria
Scientists at the Ineos Oxford Institute (IOI) have found a new potential combination therapy to combat antimicrobial resistance (AMR) by targeting two key bacterial enzymes involved in resistance. The study, "The Triple Combination of Meropenem, Avi.....»»
Blue Screen of Death: What it means and what to do if you get one
The Blue Screen of Death, or BSOD, is a common Windows error faced by many people over the years. Here's what to do if this appears on your screen......»»
Nano-drugs hitching a ride on bacteria could help treat pancreatic cancer
Many pancreatic tumors are like malignant fortresses, surrounded by a dense matrix of collagen and other tissue that shields them from immune cells and immunotherapies that have been effective in treating other cancers. Employing bacteria to infiltra.....»»
Bioreactor processes and cryotechnologies improve active ingredient tests using human cell cultures
Many new drug candidates end up failing because they cause serious side effects in clinical trials even though lab tests involving cell cultures have been successful. This is a common occurrence if the cells used come from animal tissue, for example......»»
New sugar-based catalyst could offer a potential solution for using captured carbon
A new catalyst made from an inexpensive, abundant metal and common table sugar has the power to destroy carbon dioxide (CO2) gas......»»
Understanding cellular transcription responses to oxygen deprivation
A multiprotein complex is essential for regulating cellular responses to oxygen deprivation, a key feature of cancer, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences......»»
Antimicrobial peptide from cows shows potential for treating hypervirulent bacteria
University of Central Florida College of Medicine researcher Renee Fleeman is on a mission to kill drug-resistant bacteria, and her latest study has identified a therapy that can penetrate the slime that such infections use to protect themselves from.....»»
In the Jersey suburbs, a search for rocks to help fight climate change
In early spring, George Okoko was perched on a ledge 15 feet up a crumbly cliff, trying to whack off a basketball-size piece of rock with a hammer and chisel. The locale was suburban Berkeley Heights, N.J. The rock was basalt, a common product of vol.....»»
Why do male chicks play more than females? Study finds answers in distant ancestor
Play is widespread, but far from ubiquitous, across the animal kingdom. Especially common in mammals, play is also known to occur in taxa as diverse as birds, fish, octopuses, and even insects. But what is its function, given that natural selection n.....»»
A new tool for plant long non-coding RNA identification
Long non-coding RNAs (lncRNAs) are ubiquitous transcripts with crucial regulatory roles in various biological processes, including chromatin remodeling, post-transcriptional regulation, and epigenetic modifications. While accumulating evidence elucid.....»»
Some communities are more vulnerable to weather-related power outages in New York State
Weather-related power outages in the United States have become nearly twice as common in the last 10 years compared to the previous decade. These outages, which can last most of a day, are more than an inconvenience: lack of power and related indoor.....»»