Cellular tornadoes sculpt organs
How are the different shapes of our organs and tissues generated? To answer this question, a team from the University of Geneva (UNIGE), Switzerland, forced muscle cells to spontaneously reproduce simple shapes in vitro. By confining them on adhesion.....»»
Simulation model shows ribosome tunnel"s impact on protein structures
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»
Light microscopy study reveals molecular density changes during mitotic chromosome condensation
A team of scientists studying cell division developed a special light microscopy system and used it to analyze the molecular density of cellular environments. Their results provide a novel insight into mitotic chromosome condensation in living human.....»»
Scientists use evolution to bioengineer new pathways to sustainable energy and pharmaceuticals
Using evolution as a guiding principle, researchers have successfully engineered bacteria-yeast hybrids to perform photosynthetic carbon assimilation, generate cellular energy and support yeast growth without traditional carbon feedstocks like glucos.....»»
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
A hybrid arrowhead against immune disorders: Bacterially derived natural product inhibits cellular immune response
The so-called immunoproteasome is essential for the cellular immune response. In autoimmune diseases, however, it is overactive. Until now, it has not been possible to selectively inhibit the immunoproteasome without disrupting other cellular mechani.....»»
3D-printed living cells pave way for tomorrow"s medicine and cruelty-free animal products
Researchers are expanding the possibilities of 3D printing to create miniature human organs and a variety of products made from living tissue, including food......»»
Ultra-sensitive photothermal microscopy technique detects single nanoparticles as small as 5 nm
The detection of individual particles and molecules has opened new horizons in analytical chemistry, cellular imaging, nanomaterials, and biomedical diagnostics. Traditional single-molecule detection methods rely heavily on fluorescence techniques, w.....»»
The Next Frontier for mRNA Could Be Healing Damaged Organs
Researchers are testing the use of mRNA to get damaged livers to repair themselves, in a move that could one day lessen the need for organ transplants......»»
The secret to sleepy cells" control of inflammatory secretions
Scientists at Sanford Burnham Prebys and the La Jolla Institute for Immunology have revealed a new secret regarding senescence, a cellular state similar to sleep that is more likely to affect aged cells. This drowsy condition is known to provide heal.....»»
Cryo-ET study elucidates protein folding helpers in their natural environment
Cryo-electron tomography (cryo-ET), can be used to visualize and analyze cellular structures in their natural environment. Researchers at the MPI of Biochemistry in Martinsried and the University Medical Center Göttingen have now used cryo-ET to stu.....»»
Lithospheric oddities may be sculpting continental interiors
Interactions between neighboring tectonic plates can push parts of Earth's surface up or down to form notable features, such as the Andes and the Himalayas. The forces that sculpt the Earth's surface far from plate edges are less well understood. For.....»»
Cellular DNA damage response pathways might be useful against some disease-causing viruses
New research reveals that triggering a cell's DNA damage response could be a promising avenue for developing novel treatments against several rare but devastating viruses for which no antiviral treatments exist, possibly including human papilloma vir.....»»
AT&T and Verizon ask FCC to throw a wrench into Starlink’s mobile plan
Carriers allege Starlink/T-Mobile will interfere with existing mobile networks. Enlarge (credit: T-Mobile) AT&T and Verizon are urging telecom regulators to reject a key part of SpaceX's plan to offer cellular service wi.....»»
T-Mobile has been hit with a $60 million fine. Here’s why
The third-largest cellular provider in the U.S. has been hit with a hefty fine. Here's why T-Mobile now has to pay $60 million......»»
Galadriel and Sauron meet in single combat in final Rings of Power S2 trailer
"Once the deceiver obtains a being's trust, he gains the ability to sculpt their thoughts." Morfydd Clark stars as Galadriel in the second season of Prime Video's Lord of the Rings: The Rings of Power. Fans eager to see a Galadriel/.....»»
New technology uses light to engrave erasable 3D images
Imagine if physicians could capture three-dimensional projections of medical scans, suspending them inside an acrylic cube to create a hand-held reproduction of a patient's heart, brain, kidneys, or other organs. Then, when the visit is done, a quick.....»»
Microscopy technique "paves way" for improving understanding of cellular functions
Scientists have developed a new way of counting labeled proteins in living cells that could become a standard and valuable tool in the field of biomedical research......»»
3D-printed blood vessels bring artificial organs closer to reality
Growing functional human organs outside the body is a long-sought "holy grail" of organ transplantation medicine that remains elusive. New research from Harvard's Wyss Institute for Biologically Inspired Engineering and John A. Paulson School of Engi.....»»
OpenWrt dominates, but vulnerabilities persist in OT/IoT router firmware
Forescout has published a new report examining the current state of the software supply chain in OT/IoT routers. The study uncovered that OT and IoT cellular routers and those used in small offices and homes contain outdated software components assoc.....»»
iOS 17.6 continues Emergency SOS via satellite expansion
With and later, users can contact emergency services even when there’s no Wi-Fi or cellular signal thanks to the Emergency SOS via satellite feature. This feature was first launched in the US and Canada and has since been slowly expanded to more c.....»»