Activation of prodrug using protein-encased gold catalyst
As part of their efforts to devise ways to minimize the side effects of drugs for treating cancer, four RIKEN chemists have found a biocompatible way to convert compounds with low biological activity into anticancer drugs at tumors1......»»
Researchers apply quantum computing methods to protein structure prediction
Researchers from Cleveland Clinic and IBM have recently published findings in the Journal of Chemical Theory and Computation that could lay the groundwork for applying quantum computing methods to protein structure prediction......»»
Insect frass becomes food for protein-rich microalgae
As the demand for protein-rich food increases with population growth and rising awareness of nutrition and health, traditional animal and plant-based protein sources that require arable land or freshwater put significant pressure on land and resource.....»»
A new Hungarian method may aid protein research
In a paper recently published in Nature Communications, the HUN-REN-ELTE Protein Modeling Research Group (Institute of Chemistry) has laid the foundations for a mathematical method, allowing the computer-assisted comparison of the three-dimensional s.....»»
Scientists elucidate substrate recognition and proton coupling mechanism of transporter protein VMAT2
Vesicular monoamine transporter 2 (VMAT2) is the only transporter protein in the central nervous system that mediates the storage of monoamine neurotransmitters. It plays a critical role in mediating nerve impulse transmission and neuroprotection......»»
Producing gold nano-particles (and hydrogen) in water without the need for toxic chemicals
In a surprise discovery, Flinders University nanotechnology researchers have produced a range of different types of gold nanoparticles by adjusting water flow in the novel vortex fluidic device—without the need for toxic chemicals. The article, "Na.....»»
DNA repair mechanism further elucidated in cryo-electron microscopy experiment
Researchers have discovered how the protein XPD detects severe DNA damage and controls its repair......»»
Who will like beetle skewers? What Europeans think about alternative protein food
Why do people in Paris like seaweed and tofu salad? Will Italians be tempted to try a beetle skewer? How many young Polish consumers are "food innovators," eager to eat chickpea pâté? In an international project, researchers from SWPS University an.....»»
A man who lost 40 pounds — and cut 10 inches from his waistline — recommends walking, protein swaps, and drinking vinegar water
A man who lost 40 pounds — and cut 10 inches from his waistline — recommends walking, protein swaps, and drinking vinegar water.....»»
Unveiling a novel AAK1 inhibitor: How chemical proteomics unlock therapeutic potential
Enhancing drug development for life-threatening diseases like cancer hinges on a deep understanding of protein kinases, making it a focal point for researchers. These enzymes, encoded by more than 500 human genes, serve as critical players in cellula.....»»
South Africa: Gold mine pollution is poisoning Soweto"s water and soil—study finds food gardens are at risk
For 140 years, gold mines in Johannesburg, South Africa have been leaking wastewater contaminated with heavy metals. The acid mine drainage from Johannesburg's estimated 278 abandoned mines and 200 mine dumps includes uranium (a radioactive metal), t.....»»
Scientists develop novel approach to interrogate tissue-specific protein–protein interactions
Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out.....»»
Finland"s wizards making food out of thin air
At a factory in Finland, the "farmers of the future" are making a new food protein by feeding a microbe air and electricity, proving that protein can be produced without traditional agriculture......»»
Repurposed protease controls important signaling molecule-activating protein
Efficient communication between cells is vital for many biological processes, such as recruiting immune cells to combat disease. The rapid release of at least 80 signaling molecules, including tumor necrosis factor and epidermal growth factor, is con.....»»
New catalyst transforms carbon dioxide from industrial emissions into commonly used chemicals
A low-cost, tin-based catalyst can selectively convert carbon dioxide to three widely produced chemicals—ethanol, acetic acid and formic acid......»»
Scientists" new drug-delivery technology is possible breakthrough for multi-strain vaccines
A new way to deliver drugs using a common protein could be used to develop mosaic vaccines, which are vaccines effective against multiple strains of a virus like COVID-19, among other medicines in a global first......»»
Comparison of four methods on drying efficiency and physicochemical properties of chicken meat
Chicken breast jerky (CBJ) is a popular pet food due to its high crude protein content and long shelf life. In the production of CBJ, the drying process is a crucial step. However, the physicochemical and functional properties of CBJ depend on the dr.....»»
By listening, scientists learn how a protein folds
By converting their data into sounds, scientists discovered how hydrogen bonds contribute to the lightning-fast gyrations that transform a string of amino acids into a functional, folded protein......»»
Scientists introduce DIProT—an interactive deep learning toolkit for efficient protein design
Scientists have developed DIProT, an innovative, user-friendly toolkit for protein design. The toolkit utilizes a non-autoregressive deep generative model to address the protein inverse folding problem, integrating human expertise into the design loo.....»»
Using hybrid nanotubes to enhance cancer treatment with intracellular protein delivery
The intracellular delivery of proteins is an important technique for unveiling the cellular functions, protein complex structure, and therapeutics. However, conventional delivery methods have several limitations......»»
Automotive News is Magazine of Year
Automotive News won 3 National Gold Awards and 10 regional honors in the 2024 Azbees competition, as well as 3 Jesse H. Neal Awards......»»