A comprehensive map of the SARS-CoV-2 genome
Researchers have generated what they describe as the most complete gene annotation of the SARS-CoV-2 genome. In their study, they confirmed several protein-coding genes and found that a few others that had been suggested as genes do not code for any.....»»
Scientists create comprehensive map of sea worm neural circuits
Researchers have created a detailed map of the circuits and more than 9,000 cells that make up the entire body and nervous system of a three-day-old larva of the sea worm Platynereis dumerilii......»»
Tiny TnpB: The next-generation genome editing tool for plants unveiled
Genome editing stands as one of the most transformative scientific breakthroughs of our time. It allows us to dive into the very code of life and make precise modifications. Imagine being able to rewrite the genetic instructions that determine almost.....»»
Team develops new one-step method to make multiple edits to a cell"s genome
Genome editing has become a widely adopted technology to modify DNA in cells, allowing scientists to study diseases in the lab and develop therapies that repair disease-causing mutations. However, with current approaches, it's only possible to edit c.....»»
Complete genome and toxin genes of the microalgae from the Oder River disaster decoded
In the summer of 2022, around 1,000 tons of fish, mussels and snails died in the River Oder. Although the disaster was manmade, the immediate cause of death was the toxin of a microalgae with the scientific collective name Prymnesium parvum, often re.....»»
A genome-wide screen in live hosts reveals new secrets of parasite infection
Apicomplexan parasites are a common cause of disease, infecting hundreds of millions of people each year. They are responsible for spreading malaria; cryptosporidiosis—a severe childhood diarrheal disease; and toxoplasmosis—a disease that endange.....»»
Novel strategy proposed for selectively targeting G-quadruplex at specific genome loci
DNA G-quadruplexes (G4s) are a type of quadruple helix structure formed by a continuous guanine-rich DNA sequence. Although DNA G4s are thought to be involved in various biological processes, in many cases their causative effects are largely unclear.....»»
We mapped the entire bilby genome—and now we can use poo to save Australia"s "Easter bunny" from extinction
Commonly known as Australia's "Easter bunny" due to its large ears and hopping movement, the greater bilby (Macrotis lagotis) is the last of its kind. Today we published its reference genome—all 3.66 billion pieces of it......»»
Exploring the molecular basis of how pradimicin A binds to viral N-glycan, a potential SARS-CoV-2 entry inhibitor
HIV, Ebola and most recently, COVID-19 viruses have had an enormous impact on our societies world-wide. All these viruses are "enveloped viruses," viruses that have an exterior envelope that surrounds them largely composed of their host's cells. This.....»»
How (apparently) identical animals can be completely different species
Logically speaking, you would think that animals who appeared to be the same—even if they were found in different parts of the world—would belong to the same species, and that they would share the same genome. However, our recent study has found.....»»
A 4,500-year-old collective tomb in France reveals final stage in formation of the "European genome"
High-resolution analysis of the genomes of individuals buried in a 4,500-year-old collective tomb at Bréviandes-les-Pointes, near the French town of Troyes, has revealed a surprising story with far-reaching implications. As detailed in an article in.....»»
Unveiling East Asia"s urban landscape: A massive mapping project illuminates 280 million buildings
Accurate and comprehensive building data is critical for urban management and planning. Existing datasets, such as those from Microsoft and OpenStreetMap, often lack completeness and accuracy in East Asia, limiting their utility for large-scale appli.....»»
Scientists make gains in mystery of missing snow
A major field project high in Colorado's Rocky Mountains has enabled scientists to produce the most comprehensive examination to date of how snow sublimates in a mountain environment......»»
A new way to see viruses in action: Super-resolution microscopy provides a nano-scale look
A new, nano-scale look at how the SARS-CoV-2 virus replicates in cells may offer greater precision in drug development, a Stanford University team reports in Nature Communications. Using advanced microscopy techniques, the researchers produced what m.....»»
Perplexity, one of our favorite AI apps, just got a big update
ChatGPT tool Perplexity is getting even better. With Perplexity Pages, you can transform your research into visually engaging and comprehensive content......»»
Advancing poplar genomics: Nearly gap-free genome assembly unveils new insights and applications
A research team has successfully assembled a nearly gap-free, telomere-to-telomere (T2T) genome of Populus ussuriensis, filling gaps present in the P. trichocarpa genome. Leveraging long-read sequencing, the team identified and annotated centromere r.....»»
Avoiding the cybersecurity blame game
Cyber risk management has many components. Those who do it well will conduct comprehensive risk assessments, enact well-documented and well-communicated processes and controls, and fully implemented monitoring and review requirements. Processes and c.....»»
Sweet secrets of the bayberry: Genetic insights set to transform fruit quality
The Chinese bayberry, Myrica rubra, is a subtropical fruit highly valued for its distinctive flavor, nutritional benefits, and economic importance. However, previous genome assemblies lacked sequence continuity, hindering comprehensive genetic studie.....»»
Persistent gender imbalances in UK political candidate selections: A call for systemic reform
In a comprehensive analysis by Dr. Sofía Collignon, Senior Lecturer in Comparative Politics at Queen Mary University of London, new light has been shed on the persistent gender disparities in the selection of parliamentary candidates by the U.K.'s C.....»»
Epigenetic insights: How hybrid poplar regenerates shoots
Understanding plant regeneration at the molecular level is pivotal for advancements in genetic transformation and genome editing. Previous studies have underscored the importance of DNA methylation in model organisms, yet the specific mechanisms in w.....»»
Researchers reconstruct genome of extinct species of flightless bird that once roamed the islands of New Zealand
A team of evolutionary biologists at Harvard University, working with colleagues from the Max Planck Institute for Biological Intelligence, East Carolina University, Osaka University and the University of Toronto, has reconstructed the genome of an e.....»»