Novel strategy proposed for selectively targeting G-quadruplex at specific genome loci
DNA G-quadruplexes (G4s) are a type of quadruple helix structure formed by a continuous guanine-rich DNA sequence. Although DNA G4s are thought to be involved in various biological processes, in many cases their causative effects are largely unclear.....»»
Selenoproteins open new strategies for treating certain cancers in children
Selenoproteins are crucial for several biological functions, including the breakdown of harmful substances, immune system support, and regulating metabolic processes. However, in specific contexts, these proteins can be misused and shield cancer cell.....»»
Big Bang: Trump and Musk could redefine US space strategy
Should NASA return to the moon, or go straight to Mars? Maintain its focus on climate science, or pivot away?.....»»
Hormone receptor structure reveals how it functions in heart disease
Weill Cornell Medicine researchers have determined the full-length structure of a blood pressure-regulating hormone receptor for the first time, uncovering how it functions, which may enable better drug targeting of the receptor for diseases such as.....»»
Discovery of 2,586 orphan genes in Rosa chinensis reveals stress adaptation and flower development
Orphan genes, found only in specific lineages, are key drivers of new functions and phenotypic traits. This discovery lays a foundation for understanding how roses thrive under environmental challenges......»»
A strategy of ligand-protected direct hydrogen reduction to prepare bimetallic cluster catalysts
Researchers have developed a ligand-protected direct hydrogen reduction strategy to prepare zeolite-confined Pt-Pd bimetallic cluster catalysts. These catalysts efficiently facilitate hydrogen production from ammonia borane (AB) solvolysis and the ta.....»»
Scientists engineer stable protein complexes for targeted cancer therapies
Researchers from Auburn University, partnering with the University of Basel in Switzerland, have discovered a new way to make a cancer-targeting protein complex more stable, opening doors to better cancer treatments. Led by Dr. Rafael Bernardi from A.....»»
UK consumer rights group sues Apple for maintaining an ‘unlawful’ iCloud monopoly
UK consumer rights group Which? is leading a lawsuit against Apple, targeting Apple’s dominance over cloud services on iPhone and iPad. Essentially, it argues that Apple forces iOS device users to buy iCloud storage as it does not allow other cloud.....»»
How Intel is making open source accessible to all developers
In this Help Net Security interview, Arun Gupta, Vice President and General Manager for Open Ecosystem, Intel, discusses the company’s commitment to fostering an open ecosystem as a cornerstone of its software strategy. He explains how this app.....»»
Metal-organic framework materials to remove dye contaminants for cleaner water
The future of MOFs, metal-organic framework materials, looks bright. A review in the International Journal of Environment and Waste Management has looked at how a specific class of these sponge-like materials might find increasing use in removing dye.....»»
Economic policies encourage the careless use of people and the planet. Creating caring economies is the answer
The United Nations Framework Convention on Climate Change includes a Gender Action Plan, adopted in 2017. The plan aims to "enhance the gender responsiveness" of climate policy and climate action. It outlines specific actions and strategies to promot.....»»
Squishy microgels in granular biomaterials confine and direct cell behavior
A simple biomaterial-based strategy that can influence the behavior of cells could pave the way for more effective medical treatments such as wound healing, cancer therapy and even organ regeneration, according to a research team at Penn State......»»
Scientists develop a phase-transformable membrane for efficient gas separation
Industrial gas separation, essential for clean energy and environmental protection, demands efficiency and adaptability. Current materials, however, lack the flexibility to selectively separate gases like carbon dioxide (CO2) and hydrogen (H2) while.....»»
GoIssue phishing tool targets GitHub developer credentials
Researchers discovered GoIssue, a new phishing tool targeting GitHub users, designed to extract email addresses from public profiles and launch mass email attacks. Marketed on a cybercrime forum, GoIssue allows attackers to send bulk emails while kee.....»»
Apple targeting March release for new wall-mounted smart display product: report
Apple is aiming to release its first Apple Intelligence-powered smart home device as early as March, according to a new report from Bloomberg. The product will take the form of “a wall-mounted display that can control appliances, handle videoco.....»»
How retailers change ordering strategy when a supplier starts its own direct channel
Researchers from Erasmus University and KU Leuven have published a new study that examines how retailers respond when suppliers establish direct channels to reach end-consumers and how suppliers can take steps to avoid a backlash......»»
Trump tariffs will raise prices, but Apple has set the table to avoid the worst of it
Proposed tariffs under the Trump administration could trigger considerable price increases for consumer electronics in the United States, though Apple may be able to weather the storm.Apple CEO Tim Cook [left] with Donald Trump [right]During his firs.....»»
LED light strategy deters Great White shark attacks
Surfers could be protected from future shark attacks following new discoveries about how to trick sharks' visual systems made by Professor Nathan Hart, head of Macquarie University's Neurobiology Lab, Dr. Laura Ryan and colleagues......»»
New CRISPR system for gene silencing doesn"t rely on cutting DNA
Scientists from Vilnius University's (VU) Life Sciences Center (LSC) have discovered a unique way for cells to silence specific genes without cutting DNA. This research, led by Prof. Patrick Pausch and published in the journal Nature Communications,.....»»
Trump tariffs will raise prices, but Apple could avoid harsher taxes
Proposed tariffs under the Trump administration could trigger considerable price increases for consumer electronics in the United States, though Apple may be able to weather the storm.Apple CEO Tim Cook [left] with Donald Trump [right]During his firs.....»»
Youth social media: Why proposed legislation won"t fix harms related to data exploitation
Ontario school board lawsuits against social media giants including Meta, Snapchat and TikTok are seeking damages— money paid as a remedy—for the disruption of the educational system......»»