Nanoparticle Vaccine for Many SARS-Like Coronaviruses
Researchers at the California Institute of Technology, better known as Caltech, have developed a nanoparticle vaccine that appears to confer broad protection against SARS-like betacoronaviruses. This includes SARS-CoV-2, responsible for the current p.....»»
Breaking boundaries in tiny labs: New technology using sound waves has implications for nanoparticle manipulation
Acoustofluidics elegantly merges acoustics with fluid mechanics, enabling precise manipulation of fluids and particles on both micro and nanoscales. This interdisciplinary field plays a crucial role in biomedicine, tissue engineering, and nanoparticl.....»»
Arboviruses, mosquitoes and potential hosts tracked in real time in São Paulo city
The technology used to sequence SARS-CoV-2 at record speed early in the COVID-19 pandemic has been successfully tested as a technique to monitor arboviruses and diseases transmitted mainly by mosquitoes......»»
Nanoparticle delivery of FZD4 to lung endothelial cells inhibits lung cancer progression and metastases
A recent study from the lab of Tanya Kalin, MD, Ph.D., professor of Child Health and Internal Medicine at the University of Arizona College of Medicine—Phoenix, has shown potential to improve therapeutic outcomes for patients suffering from lung ca.....»»
Republicans who support childhood vaccine mandates often stay silent, research suggests
Most Republican voters support childhood vaccine mandates, yet may be discouraged from publicly expressing these views, a new study suggests......»»
Scientists report that buffer and pH strongly affect the phase separation of SARS-CoV-2 N protein
In a new paper published in Molecular Biology of the Cell, the Allain lab (IBC) reported that the phase separation of the SARS-CoV-2 N protein strongly depends on the chosen buffer and pH. For example, the protonation of a single histidine side chain.....»»
Study describes zinc oxide nanoparticle strategy for inactivation of multidrug-resistant bacteria
An article published in the Journal of Environmental Chemical Engineering describes a possible strategy for promoting selective inhibition of multidrug-resistant bacteria, which are increasingly abundant owing to the indiscriminate use of antibiotics.....»»
Must mRNA be cloaked in a lipid coat to serve as a vaccine?
The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus causing COVID-19, in mic.....»»
Tuberculosis vaccine may enable elimination of the disease in cattle by reducing its spread
Vaccination not only reduces the severity of TB in infected cattle, but reduces its spread in dairy herds by 89%, research finds. The research, led by the University of Cambridge and Penn State University, improves prospects for the elimination and c.....»»
Chemists develop method to confirm mRNA vaccine stability
University at Albany researchers at the RNA Institute have developed a new method to test COVID-19 vaccine integrity that could allow anyone with basic skills in vaccine handling to detect expired vaccines quickly and effectively, without specialized.....»»
Can mRNA vaccines help boost livestock production?
University of Queensland researchers say mRNA vaccine technology could play an important role in boosting livestock production to meet global food demands......»»
Nanoparticles target multiple COVID variants through the twist in the spike protein
Teardrop-shaped particles designed to inactivate multiple strains of the SARS-CoV-2 virus could one day complement existing treatments for COVID-19, according to a new study led by researchers at the University of Michigan and Jiangnan University in.....»»
New bioengineered protein design shows promise in fighting COVID-19
In the wake of the COVID-19 pandemic, scientists have been racing to develop effective treatments and preventatives against the virus. A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus re.....»»
"GPS nanoparticle" platform precisely delivers therapeutic payload to cancer cells
A newly developed "GPS nanoparticle" injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers from Penn State. They tested their approach in human cel.....»»
Q&A: How Instagram influencers profit from anti-vaccine misinformation
While Instagram might have a reputation for superficiality—a realm of exquisitely filtered images—it is now eclipsing other social media as a news source. The platform is increasingly filled with information, some of it pernicious and distributed.....»»
Early experiments show Ebola-fighting potential of engineered bacteria
Since its 1976 emergence in Africa, the Ebola virus has proven an especially lethal contagion, killing roughly 50% of the people who contract it. The 2019 FDA approval of a vaccine, combined with the subsequent development of two antibody-based drugs.....»»
Scientists use a new type of nanoparticle that can both deliver vaccines and act as an adjuvant
Many vaccines, including vaccines for hepatitis B and whooping cough, consist of fragments of viral or bacterial proteins. These vaccines often include other molecules called adjuvants, which help to boost the immune system's response to the protein......»»
Research milestone reached as healthy koala leaves treatment program
In a research milestone, the first koala to receive the QUT-developed chlamydia vaccine has been released from the program and back into the wild......»»
CDC recommends spring COVID booster for people 65 and up
The shot should be taken at least four months since the last COVID vaccination. Enlarge / The Moderna Spikevax COVID-19 vaccine is shown at a CVS in 2023. (credit: Getty | Melissa Phillip/Houston Chronicle ) People ages.....»»
How the SARS-CoV-2 virus acquires its spherical shape
For centuries, coronaviruses have triggered health crises and economic challenges, with SARS-CoV-2, the coronavirus that spreads COVID-19, being a recent example. One small protein in SARS-CoV-2, the membrane protein, or M protein, is the most abunda.....»»
New molecules, inspired by space shuttles, advance lipid nanoparticle delivery for weight control
Inspired by the design of space shuttles, Penn Engineering researchers have invented a new way to synthesize a key component of lipid nanoparticles (LNPs), the revolutionary delivery vehicle for mRNA treatments including the Pfizer-BioNTech and Moder.....»»