Nanoparticle delivery of FZD4 to lung endothelial cells inhibits lung cancer progression and metastases
A recent study from the lab of Tanya Kalin, MD, Ph.D., professor of Child Health and Internal Medicine at the University of Arizona College of Medicine—Phoenix, has shown potential to improve therapeutic outcomes for patients suffering from lung ca.....»»
New discovery of a mechanism that controls cell division
Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of.....»»
Researchers develop "founding document" on synthetic cell development
Cells are the fundamental units of life, forming the variety of all living things on Earth as individual cells and multicellular organisms. To better understand how cells perform the essential functions of life, scientists have begun developing synth.....»»
Nano-drugs hitching a ride on bacteria could help treat pancreatic cancer
Many pancreatic tumors are like malignant fortresses, surrounded by a dense matrix of collagen and other tissue that shields them from immune cells and immunotherapies that have been effective in treating other cancers. Employing bacteria to infiltra.....»»
Delivery van safety features could mitigate 4 in 10 fatal crashes, study says
Larger vehicles are more likely to cause injuries in crashes because of their greater mass, and the victims are often outside the vehicle......»»
Bioreactor processes and cryotechnologies improve active ingredient tests using human cell cultures
Many new drug candidates end up failing because they cause serious side effects in clinical trials even though lab tests involving cell cultures have been successful. This is a common occurrence if the cells used come from animal tissue, for example......»»
Understanding cellular transcription responses to oxygen deprivation
A multiprotein complex is essential for regulating cellular responses to oxygen deprivation, a key feature of cancer, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences......»»
Study: Airway hillocks challenge our understanding of lung biology
Airway hillocks are mysterious, flat-topped structures that were only recently identified within regular lung tissue, and their role in airway biology and pathology has previously been unknown......»»
Cell contraction drives the initial shaping of human embryos, study finds
Human embryo compaction, an essential step in the first days of an embryo's development, is driven by the contractility of its cells. This is the finding of a team of scientists from CNRS, Institut Curie, Inserm, AP-HP and the Collège de France. Pub.....»»
Study uncovers the secret of long-lived stem cells
Nothing lives forever, but compared to other cells in the body, hematopoietic stem cells (HSCs) are remarkably long-lived. HSCs are blood-forming cells—they give rise to rapidly dividing progenitor cells, which in turn generate hundreds of billions.....»»
Researchers suggest that mechanical pressure triggers a key event in HIV infection
It has been more than 40 years since the beginning of the HIV/AIDS epidemic and scientists still don't fully understand how HIV enters and replicates in human cells, which has hindered the development of treatments......»»
Motherboard makers apparently to blame for high-end Intel Core i9 CPU failures
Motherboard makers "disable thermal and power delivery safeguards" by default. Enlarge / Intel's top-end i9-14900KS. (credit: Intel) Earlier this month, we wrote that some of Intel's recent high-end Core i9 and Core i7.....»»
Study reveals cancer vulnerabilities in popular dog breeds
Medium-sized dogs have a higher risk of developing cancer than the very largest or smallest breeds, according to a UC Riverside study......»»
Scientists" research on RNA editing illuminates possible lifesaving treatments for genetic diseases
A team at Montana State University published research this month that shows how RNA, the close chemical cousin to DNA, can be edited using CRISPRs. The work reveals a new process in human cells that has potential for treating a wide variety of geneti.....»»
Cartilage healing discovery in animal models could lead to new human therapies
Researchers hope their discovery about the healing properties of fetal cartilage cells in mice will lay the groundwork for new treatments for human growth disorders and degenerative diseases......»»
Fruit fly helps unlock clues about how organs, tissue and cancer grow
The fruit fly, Drosophila, has been used by scientists for more than 100 years to unravel key features of life on Earth, such as how animals respond to the sun and how the bodies of animals are patterned from head to tail......»»
Did climate chaos cultivate or constrain 2023"s greenery?
In the ongoing quest to track the progression of climate change, scientists frequently examine the state of our planet's vegetation—forests, grasslands, agricultural lands, and beyond......»»
Scientists combine a spatially distributed sediment delivery model and biogeochemical model to estimate fluxes by water
Water erosion is the most active process controlling soil formation and evolution, which can affect the redistribution of carbon between terrestrial, aquatic, and atmospheric ecosystems. Erosion-induced organic carbon dynamic process should not be mi.....»»
Study reveals protein"s key role in helping cilium transmit signals to the rest of the cell
The essential role played by a protein in the functioning of cells is revealed in new work from the laboratory of Université de Montréal medical professor Frédéric Charron, holder of the Canada Research Chair in Developmental Neurobiology......»»
Scientists regenerate neural pathways in mice with cells from rats
Two independent research teams have successfully regenerated mouse brain circuits in mice using neurons grown from rat stem cells. Both studies, published April 25 in the journal Cell, offer valuable insights into how brain tissue forms and present n.....»»
IRIS beamline at BESSY II gets a new nanospectroscopy end station
The IRIS infrared beamline at the BESSY II storage ring now offers a fourth option for characterizing materials, cells and even molecules on different length scales. The team has extended the IRIS beamline with an end station for nanospectroscopy and.....»»