Nanoparticle delivery of FZD4 to lung endothelial cells inhibits lung cancer progression and metastases
A recent study from the lab of Tanya Kalin, MD, Ph.D., professor of Child Health and Internal Medicine at the University of Arizona College of Medicine—Phoenix, has shown potential to improve therapeutic outcomes for patients suffering from lung ca.....»»
New understanding of a cancer-relevant protein reveals opportunities for drug discovery
A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights into how it functions......»»
Scientists develop self-sustained protein transport and tissue assembly in artificial cells
In a new Nature Communications study, scientists have developed a novel method for artificial cells to interact with their external environment without the need for complex modification processes......»»
State surveillance: Kenyans have a right to privacy—does the government respect it?
The Kenyan government is using technology to improve governance, service delivery and national security. The progress, while welcome, has brought with it concerns about state surveillance, data protection, and violations of fundamental rights and fre.....»»
Toxic site is leaking cancer-causing chemicals in Grand Prairie, Texas: When will it be cleaned?
The Environmental Protection Agency has finalized a plan to clean a toxic site leaking cancer-causing chemicals under dozens of homes in Grand Prairie, Texas......»»
Bio-inspired droplet-based systems herald a new era in biocompatible devices
Oxford University researchers have made a significant step toward realizing a form of "biological electricity" that could be used in a variety of bioengineering and biomedical applications, including communication with living human cells. The work wa.....»»
Nanopesticide delivery system made with neem seed extract improves pesticide effectiveness
Pesticides can be made more effective and environmentally friendly by improving how they stick to plant surfaces, thanks to new research led by Dr. Mustafa Akbulut, professor of chemical engineering at Texas A&M University......»»
A matter of time: New research shows how tissue development is temporally organized
When a vertebrate embryo develops, a group of cells self-organizes into the neural tube, eventually becoming the brain and the spinal cord. This involves specific signals, but how these signals are interpreted by developing cells remains unclear. A t.....»»
Cell model identifies important factor in neural development
The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular "bridge" complex demonstrate a new level of detail in the under.....»»
Scientists successfully use harmless viruses to investigate the nervous system in frogs
Virus. When you hear the word, you probably shudder. But not all viruses are bad or cause disease. Some are even used for therapeutic applications or vaccination. In basic research, they are often employed to infect certain cells, genetically modify.....»»
Better health diagnostics through genetically engineered embedded sentinel cells
Cells can now be genetically programmed to record their histories within their genomes, a development that could revolutionize the study of developmental and disease processes, according to a collaborative work by researchers from multiple institutio.....»»
Researchers develop light-guided siRNA delivery system based on cyanobacteria
In a study published in Cell Reports Physical Science on Nov. 25, a research team reported the development of an innovative intelligent light-guided biohybrid system, the CTPA/siCSF1R system, to target tumor-associated macrophages (TAMs), thus enabli.....»»
This week"s space station science: Leads on cancer drugs, satellite sustainability, glass from magnesium silicates
Recent findings from the International Space Station address.....»»
Exploring life at its simplest: Scientists create a "minimal cell membrane" with just two lipids
Lipids, or fats, are essential to life. They form the membranes around cells, protecting them from the outside. In nature, there is an enormous diversity of lipids, with each organism having its own unique combination. But what are the minimum lipid.....»»
Tweaking non-neural brain cells can cause memories to fade
Neurons and a second cell type called an astrocyte collaborate to hold memories. “If we go back to the early 1900s, this is when the idea was first proposed that memories are ph.....»»
Improved ultrasound technique produces previously unattainable images inside live cells
A ultrasound technique from the University of Nottingham will allow the production of sharper images inside live cells without causing damage at resolutions that were previously unattainable......»»
Nano-patterned copper oxide sensor provides rapid ultra-low hydrogen detection
Hydrogen is becoming an increasingly popular choice as we shift towards cleaner energy. It can be burned like traditional fuels, producing only water as a byproduct, and can generate electricity when used in fuel cells. However, as hydrogen productio.....»»
Engineers refine lipid nanoparticles for better mRNA therapies
Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids—key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 vaccines and other innovative therapies. The meth.....»»
Study reveals RNA"s unknown role in DNA damage repair
A multi-institutional team of researchers, led by Georgia Tech's Francesca Storici, has discovered a previously unknown role for RNA. Their insights could lead to improved treatments for diseases like cancer and neurodegenerative disorders while chan.....»»
Using gas bubbles to precisely deliver nanomedicines shows promise for lung cancer treatment
The delivery of nanomedicines using gas bubbles has shown itself to be a unique way of transporting cytotoxins to the lungs of cancer patients. The method enables precise and focused treatments, and the local action of the drugs also prevents a range.....»»
Transparent worms with glowing proteins may help fertility treatments
The development of maternal egg cells is pivotal for survival—but also precarious. During meiosis, the DNA-containing chromosomes can easily be broken or lost, causing infertility, miscarriage or genetic disorders like Down syndrome. Scientists hav.....»»