Why some drug traffickers are more likely to be reconvicted than others
One in two "typical" drug traffickers convicted in NSW between 2000 and 2023 will have no further contact with the criminal justice system after release, according to an Australian-first study published in the International Journal of Drug Policy......»»
Nano drug delivery system eliminates need for complicated carriers
A team of University of Melbourne researchers from the Caruso Nanoengineering Group has created an innovative drug delivery system with outstanding potential to improve drug development......»»
Why some drug traffickers are more likely to be reconvicted than others
One in two "typical" drug traffickers convicted in NSW between 2000 and 2023 will have no further contact with the criminal justice system after release, according to an Australian-first study published in the International Journal of Drug Policy......»»
“Unprecedented” decline in teen drug use continues, surprising experts
Kids who were in 8th grade at pandemic's start have ushered in an era of abstaining. Teen drug use continued to fall in 2024, extending a dramatic decline spurred by the COVID-19.....»»
The kids are… maybe alright: Teen drug use hits new lows in ongoing decline
Kids who were in 8th grade at pandemic's start have ushered in an era of abstaining. Teen drug use continued to fall in 2024, extending a dramatic decline spurred by the COVID-19.....»»
Boltz-1: Fully open-source model rivals AlphaFold3 for predicting biomolecular structures
MIT scientists have released a powerful, open-source AI model called Boltz-1 that could significantly accelerate biomedical research and drug development. The paper is available on the bioRxiv preprint server......»»
Protein"s "hopping" behavior uncovers new drug development avenues
Since 2006, Ruben Gonzalez's Columbia lab has used single-molecule light microscopy to study the structural dynamics of biomolecules......»»
Analysis provides new insights into the replication of BK polyomavirus, a major cause of kidney transplant failure
BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research at the University of Alabama at Birmingham reveals new aspects of BKPyV replication, offering possible drug targets to pro.....»»
Peer-brokered sales central to illegal drug trade
The thought of illegal drug sales evokes images of deals done on shady street corners. But a new study from Case Western Reserve University exposes a critical but underreported element of the illegal drug market: so-called "peer-brokered" sales......»»
Russian court sentences kingpin of Hydra drug marketplace to life in prison
The underground marketplace distributed more than a metric ton of narcotics. A Russian court has issued a life sentence to a man found guilty of being the kingpin of a dark web dr.....»»
Open-source platform supports large imaging data analysis of single cell responses to manipulation
Modern day drug discovery is shifting from single end point assays to more complex phenotypic assays that query single cell and population responses to chemicals and genetic manipulation......»»
New understanding of a cancer-relevant protein reveals opportunities for drug discovery
A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights into how it functions......»»
Modified ribosomes could be a possible mechanism of antibiotic resistance
Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published in Nature Communications. The subtle changes might be enough to alter the binding site of drug targets and constitute a possible new mechanism of.....»»
Parasite genome analysis provides a new approach to predicting malaria drug resistance
Researchers at University of California San Diego analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug resistance......»»
Scientists synthesize unsymmetrical ureas using non-phosgene method
Unsymmetrical ureas can form multiple stable hydrogen bonds with proteins. Since drugs containing urea functional groups display unique biological activities when interacting with their targets, they play an important role in drug development and med.....»»
Trump targets Mexico and Canada with tariffs, plus an extra 10% for China
Tariffs are retaliation for drug trafficking and illegal migration. Donald Trump has said he will impose tariffs of 25 percent on all imports from Canada and Mexico, and an extra.....»»
A molecular trap for exotic metals promises improved diagnostics and faster drug development
A group of scientists from IOCB Prague, led by Dr. Miloslav Polášek, have created compounds that are up to a million times more stable than similar substances used in contemporary medicine to treat tumors or as contrast agents for magnetic resonanc.....»»
Light-activated, drug-carrying liposomes show potential for minimally invasive glaucoma treatments
More than 4 million people in the U.S. have glaucoma, a group of eye diseases that can damage the optic nerve and lead to vision loss. It's the second-leading cause of blindness worldwide and there's currently no cure, but there's a way to help preve.....»»
Sugar-like nanoparticle covering could boost cancer drug delivery
A spoonful of sugar might actually help medicine go down, according to recent research from the University of Mississippi. And it could reduce the harmful side effects of cancer treatment. Instead of a literal spoonful of sugar, however, the research.....»»
Engineered antibiotic D22 shows promise against drug-resistant bacteria
Antibacterial drugs are important for treating infections. But increasingly, bacterial resistance to current drugs—so they don't work well, or even at all—means new ones are urgently needed......»»
Novo Nordisk sells hit weight-loss drug in China—at fraction of US price
As US struggles to afford GLP-1 drugs, the rest of the world sees much lower prices. Patients in China will be able to purchase the blockbuster weight-loss drug Wegovy for 1,400 y.....»»