Where the heck did all those structures inside complex cells come from?
There are competing theories about the origin of the nucleus and endoplasmic reticulum. Enlarge / Computer illustration of mitochondria, membrane-enclosed cellular organelles that produce energy. (credit: KATERYNA KON/SCIENCE PHO.....»»
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
What makes a supercluster?
By eye, it's impossible to pick out the exact boundaries of the superclusters, which are among the largest structures in the universe. But that's because they are not defined by their edges, but by the common motion of their components......»»
Unlocking crop yield potential: New modeling approach for sustainable agriculture
Predicting crop yields is a significant challenge in modern agriculture, especially under fluctuating environmental conditions. With the escalating demand for sustainable food production, understanding the complex interplay between environmental fact.....»»
Canada to slap tariffs on EVs, steel from China
Canada, an export-driven economy that relies heavily on trade with the U.S., has been closely watching moves by the Biden administration to erect a much higher tariff wall against Chinese EVs, batteries, solar cells, steel and other products......»»
Hybrid imaging approach reveals microbes in 3D
Caltech researchers have developed a new method to create three-dimensional images of complex communities of bacteria and plant roots. The technology synthesizes two traditional methods of imaging: visualizing microbes with fluorescence and a noninva.....»»
3D-printed living cells pave way for tomorrow"s medicine and cruelty-free animal products
Researchers are expanding the possibilities of 3D printing to create miniature human organs and a variety of products made from living tissue, including food......»»
The promise of synthetic cells
For over a decade, scientists have made extraordinary progress on the long-held dream of fabricating an entire cell from nonliving molecules and materials......»»
Study highlights new advancements to simulate multiscale coastal processes
Simulating flooding where rivers meet the ocean is challenging because existing Earth system models struggle to capture the complex interactions between river flows, ocean tides, and storm surges......»»
As EV sales slump, Volkswagen scales back battery factories buildout
VW might only need 170 GWh of cells in 2030 if demand stays depressed. Enlarge / A VW worker on the assembly line at Emden in Germany. (credit: Volkswagen) Volkswagen will wait to see what electric car demand is like be.....»»
Researchers synthesize molecular aggregates for solar energy applications
No molecule stands alone—they need others, at least when it comes to being able to display useful photophysical, electronic, and chemical properties. When individual molecules combine into an aggregate, or a complex of two or more molecules, they b.....»»
New approach for profiling complex dynamics at the single-molecule level
A team of researchers led by Professor Sebastian Deindl at Uppsala University has developed a pioneering method that vastly improves the ability to observe and analyze complex biological processes at the single-molecule level. Their work is published.....»»
Single nucleosomes tracked in live cells during cell division using super-resolution microscopy
Individual cells divide through a process called mitosis, during which the cell's copied DNA is separated between two resulting daughter cells. Despite recent advances in cell biology, the mechanism by which DNA condenses during mitosis is still poor.....»»
The secret to sleepy cells" control of inflammatory secretions
Scientists at Sanford Burnham Prebys and the La Jolla Institute for Immunology have revealed a new secret regarding senescence, a cellular state similar to sleep that is more likely to affect aged cells. This drowsy condition is known to provide heal.....»»
A small molecular glue that increases P53 level and suppresses tumor growth in vivo
Molecular glues are typically small chemical molecules that act on the interface between the target protein and the degradation machinery to trigger ternary complex formation. Identification of molecular glues is challenging, and there has been a lac.....»»
Novel silica nonwoven fabric scaffold enhances understanding of cell-to-cell interactions
Communication and coordination among different cells are fundamental aspects that regulate many functions in our body. This process, known as paracrine signaling, involves the release of signaling molecules by a cell into its extracellular matrix (EC.....»»
New study uncovers the complex dynamics of self-deprecating remarks in Korean entertainment
Self-deprecation, a negative self-assessment used in social interaction, is prevalent in Korean reality TV shows. Traditionally, psychology views self-deprecation as indicative of low self-esteem or related psychological disorders, such as depression.....»»
Cryo-ET study elucidates protein folding helpers in their natural environment
Cryo-electron tomography (cryo-ET), can be used to visualize and analyze cellular structures in their natural environment. Researchers at the MPI of Biochemistry in Martinsried and the University Medical Center Göttingen have now used cryo-ET to stu.....»»
Tissue fluidization during skin repair is crucial for wound healing, study reveals
The ability to repair tissue following injuries is essential for the survival of all animals. Following wounding, the skin is repaired by activating, migrating, and dividing skin stem cells. Defects of wound healing in humans lead to chronic wounds t.....»»
Surprising mechanism for removing dead cells identified
Billions of our cells die every day to make way for the growth of new ones. Most of these goners are cleaned up by phagocytes—mobile immune cells that migrate where needed to engulf problematic substances. But some dying or dead cells are consumed.....»»
Physicists develop new model that describes how filaments assemble into active foams
Many fundamental processes of life, and their synthetic counterparts in nanotechnology, are based on the autonomous assembly of individual particles into complex patterns. LMU physicist Professor Erwin Frey, Chair of Statistical and Biological Physic.....»»