When mad AIOLOS drags IKAROS down: A novel pathogenic mechanism
Researchers have described a novel primary immunodeficiency due to a mutation in AIOLOS. This acts through a novel pathogenic mechanism termed 'heterodimeric interference', whereby when two different proteins bind together in a heterodimer, the mutan.....»»
Research identifies mechanism behind drug resistance in malaria parasite
Collaborating researchers have discovered a link between malaria parasites' ability to develop resistance to antimalarial drugs—specifically artemisinin (ART)—through a cellular process called transfer ribonucleic acid (tRNA) modification. tRNA m.....»»
Researchers unlock vital insights into metal-nitrogen-carbon catalysts" reaction mechanism
A team of researchers has made significant strides in understanding metal-nitrogen-carbon (M-N-C) catalysts, offering alternatives to expensive platinum-group-metal (PGM) catalysts and a pathway to a greener future......»»
Avian flu detected in New York City wild birds
A small number of New York City wild birds carry highly pathogenic H5N1 avian influenza, according to a study published in the Journal of Virology,. The work highlights that the interface between animals and humans that may give rise to zoonotic infe.....»»
Researchers uncover mechanism for short-distance vesicle movements
Researchers at the Hong Kong University of Science and Technology (HKUST) have thrown new light on the mechanism for how vesicles move short distances within specific parts of the cell, an area not understood by scientists......»»
Team develops an epigenome editing toolkit to dissect the mechanisms of gene regulation
Understanding how genes are regulated at the molecular level is a central challenge in modern biology. This complex mechanism is mainly driven by the interaction between proteins called transcription factors, DNA regulatory regions, and epigenetic mo.....»»
Study reveals new mechanism to explain how continents stabilized
Ancient, expansive tracts of continental crust called cratons have helped keep Earth's continents stable for billions of years, even as landmasses shift, mountains rise and oceans form. A new mechanism proposed by Penn State scientists may explain ho.....»»
Study pinpoints cellular response to pressure in sea star embryos
An international team of scientists has discovered a new cellular mechanism that explains how cells can adapt to pressure changes during tissue growth by packing themselves into a unique shape......»»
Experts provide facts about avian influenza for dairy producers
While a strain of highly pathogenic avian influenza virus has been detected in dairy cattle in nine states—not including New York state—the commercial milk supply continues to be safe, according to a panel of Cornell, New York state and dairy ind.....»»
Male or female? Scientists discover the genetic mechanism that determines sex development in butterflies
Scientists of the Biology Centre, Czech Academy of Sciences, in collaboration with University of Liverpool have found the genetic mechanism that determines whether individuals of the butterfly species Bicyclus anynana become male or female......»»
New discovery of a mechanism that controls cell division
Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of.....»»
Discovery of mechanism plants use to change seed oil could impact industrial, food oils
Researchers have discovered a new mechanism of oil biosynthesis and found a way to genetically engineer a type of test plant to more efficiently produce different kinds of seed oil that it otherwise wouldn't make......»»
Adaptation of photosynthetic mechanism in air plants occurs through gene duplication, study finds
Researchers at the University of Vienna, along with collaborators from France, Germany, Switzerland and the U.S., have achieved a breakthrough in understanding how genetic drivers influence the evolution of a specific photosynthesis mechanism in Till.....»»
NASA lays out how SpaceX will refuel Starships in low-Earth orbit
"The fundamental flow mechanism is the pressure delta across the umbilical." Enlarge / Artist's illustration of two Starships docked belly-to-belly in orbit. (credit: SpaceX) Some time next year, NASA believes SpaceX wi.....»»
New study reveals mystery of decaying exoplanet orbits
A new study led by researchers at Durham University has uncovered a novel mechanism that could solve a long-standing mystery about decaying planetary orbits around stars like our sun......»»
Florida dolphin found with highly pathogenic avian flu: Report
The case of a Florida bottlenose dolphin found with highly pathogenic avian influenza virus, or HPAIV—a discovery made by University of Florida researchers in collaboration with multiple other agencies and one of the first reports of a constantly g.....»»
Molecular mechanism of CmoDREB2A and CmoNAC1 in pumpkin regulating the salt tolerance of grafted cucumber revealed
In February 2024, a research article titled "Pumpkin CmoDREB2A enhances salt tolerance of grafted cucumber through interaction with CmoNAC1 to regulate H2O2 and ABA signaling and K+/Na+ homeostasis" was published by Professor Zhilong Bie's team from.....»»
Mechanism of grafting Prunus sp. to control crown gall disease by regulating the rhizosphere environment
Grafting is a traditional and significant strategy to suppress soil-borne diseases, such as the crown gall disease caused by tumorigenic Agrobacterium and Rhizobium. Root exudates and the rhizosphere microbiome play critical roles in controlling crow.....»»
Researchers discover mechanism regulating bud dormancy release in tree peony
In perennial woody plants, bud endodormancy is crucial for survival under adverse environmental conditions in winter, such as low temperature (LT) and dehydration stress. To break bud dormancy is essential for the resumption of bud growth and floweri.....»»
Supercomputer simulation reveals new mechanism for membrane fusion
An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world's most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse......»»
Key protein regulates immune response to viruses in mammal cells
Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and.....»»