What If Cells Kept Receipts of Their Gene Expression?
Researchers have found a new way to keep records of when a cell’s genes turn on and off—by harnessing systems that bacteria already use for self-defense......»»
Enhanced CRISPR method enables stable insertion of large genes into the DNA of higher plants
Scientists at the Leibniz Institute of Plant Biochemistry (IPB) have succeeded for the first time in stably and precisely inserting large gene segments into the DNA of higher plants very efficiently. To do this, they optimized the gene-editing method.....»»
Scientists study lipids cell by cell, making new cancer research possible
Imagine being able to look inside a single cancer cell and see how it communicates with its neighbors. Scientists are celebrating a new technique that lets them study the fatty contents of cancer cells, one by one......»»
Researchers create artificial cells that act like living cells
In a new study published in Nature Chemistry, UNC-Chapel Hill researcher Ronit Freeman and her colleagues describe the steps they took to manipulate DNA and proteins—essential building blocks of life—to create cells that look and act like cells f.....»»
Researchers report on mechanisms of gene regulatory divergence between species
Closely related animal species can look physically different, but you might be surprised to learn that those differences can result not only from DNA sequence changes that alter proteins' structure or function, but also because changes in the DNA aff.....»»
Pressure in the womb may influence facial development
Physical cues in the womb, and not just genetics, influence the normal development of neural crest cells, the embryonic stem cells that form facial features, finds a new study led by UCL researchers......»»
Diamond-based quantum sensing microscope offers effective approach for quantifying cellular forces
Cells rely on constant interplay and information exchange with their micro-environment to ensure their survival and perform biological functions. Hence, precise quantification of tiny cellular adhesion forces, spanning from piconewtons to a few nanon.....»»
Uncovering key players in gene silencing: Insights into plant growth and human diseases
Monash University biologists have shed light on the intricate molecular mechanisms that are responsible for gene silencing induced by expanded repeats in an international study published today in Nature Plants......»»
Light show in living cells: New method allows simultaneous fluorescent labeling of many proteins
Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge—especially in living cells, as the required fluorescent labeling had to be individually attached to each p.....»»
Key protein regulates immune response to viruses in mammal cells
Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and.....»»
Researchers crack mystery of swirling vortexes in egg cells
Egg cells are the largest single cells on the planet. Their size—often several to hundreds of times the size of a typical cell—allows them to grow into entire organisms, but it also makes it difficult to transport nutrients and other molecules ar.....»»
Mobile genetic elements can inadvertently suppress bacterial immune systems, research reveals
Bacterial restriction-modification systems are responsible for protecting cells from foreign genetic material, for example, bacteriophages and plasmids. Immune systems require strict regulation, as bacteria, like humans, can have autoimmune reactions.....»»
Saturn"s ocean moon Enceladus could support life—researchers are working out how to detect extraterrestrial cells there
Saturn has 146 confirmed moons—more than any other planet in the solar system—but one called Enceladus stands out. It appears to have the ingredients for life......»»
Computer model suggests frozen cells could be used to save northern white rhino from extinction
A team of geneticists and computer scientists from the San Diego Zoo Wildlife Alliance, Cornell University and the University of California, Santa Cruz, has created a computer model that shows it should be possible to save the northern white rhino fr.....»»
Researchers uncover human DNA repair by nuclear metamorphosis
Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging......»»
Nanoparticle delivery of FZD4 to lung endothelial cells inhibits lung cancer progression and metastases
A recent study from the lab of Tanya Kalin, MD, Ph.D., professor of Child Health and Internal Medicine at the University of Arizona College of Medicine—Phoenix, has shown potential to improve therapeutic outcomes for patients suffering from lung ca.....»»
Researchers find cryptic genetic element in the human gut that could serve as a sensitive biomarker
A component of the human intestinal flora that has been little studied to date is the focus of a new study from Germany. Plasmids are small extrachromosomal genetic elements that frequently occur in bacterial cells and can influence microbial lifesty.....»»
Nanovials method for immune cell screening uncovers receptors that target prostate cancer
A recent UCLA study demonstrates a new process for screening T cells, part of the body's natural defenses, for characteristics vital to the success of cell-based treatments. The method filters T cells based on the receptor proteins found on their sur.....»»
Discovery of organic catalyst could lead to cheaper fuel cells
With atmospheric carbon dioxide at record highs, the search for clean-energy alternatives to the use of fossil fuels is growing increasingly urgent......»»
Researchers discover previously unknown gene that indirectly promotes photosynthesis in blue-green algae
Cyanobacteria—also called blue-green algae—are known as the "plants of the ocean" because they carry out photosynthesis on a gigantic scale, produce oxygen and extract the greenhouse gas CO2 from the environment. However, to do this they need add.....»»
A rechargeable nanotorch: Afterglow luminescence imaging tracks cell-based microrobots in real time
An afterglow luminescent nanoprobe opens up new possibilities for imaging living cells. As a research team reports in the journal Angewandte Chemie International Edition, their new "nanotorch" can continue to luminesce for more than 10 days after a s.....»»