Venomous Snail Unlocks New Diabetes Drugs
A cone snail’s poison helps to form a fast-acting insulin -- Read more on ScientificAmerican.com.....»»
Path to precision: Targeted cancer drugs go from table to trials to bedside
What started in a scientist's dining room is now in tissue-agnostic combo trials. Enlarge (credit: Aurich Lawson) In 1972, Janet Rowley sat at her dining room table and cut tiny chromosomes from photographs she had taken.....»»
Buying shady weight loss drugs online is a bad idea, in case you were wondering
Buying shady weight loss drugs online is a bad idea, in case you were wondering.....»»
Scientists reveal transport mechanism of norepinephrine transporter and binding mode of small molecule and peptide drugs
Noradrenaline (NA) is an important monoamine neurotransmitter in the nervous system. The noradrenaline transporter (NET) located on the presynaptic membrane can transport NA into presynaptic neurons......»»
Electrical impedance tomography plus extracellular voltage activation technique simplifies drug screening
When developing new drugs, understanding their effects on ion channels in the body, such as the human ether-a-go-go-related gene (hERG) ion channel found in neurons and heart muscle cells, is critical. Blocking hERG channels can disrupt a normal hear.....»»
Weight loss drugs like Ozempic can also help people stop smoking
Drugs containing semaglutide, like Ozempic and Wegovy, are intended to help people with diabetes lower their blood glucose levels while also reducing the risk of … The post Weight loss drugs like Ozempic can also help people stop smoking appear.....»»
A new model to study regeneration of brown adipose tissues
The prevalence of obesity worldwide has led to an increase in the risk of metabolic diseases and socio-economical burdens. Brown adipose tissue (BAT) has been established as a promising therapeutic target to overcome obesity, type 2 diabetes (T2D) an.....»»
Mass breeding of desert locusts unlocks new food source
Mass breeding of desert locusts in a controlled environment could provide a sustainable source of protein for animals and humans as well as business opportunities in Sub-Saharan Africa, researchers say......»»
"Russian doll" packaging could boost drug delivery
New technology, which is in the early stages of development, has the potential to significantly enhance the effectiveness and reduce the side effects of drugs and vaccines......»»
People are overdosing on off-brand weight-loss drugs, FDA warns
Bad math and unclear directions are behind overdoses of up to 20 times the normal amount. Enlarge / Wegovy is an injectable prescription weight-loss medicine that has helped people with obesity. (credit: Getty | Michael Siluk).....»»
The Race for the Next Ozempic
The next wave of obesity drugs could help people lose even more weight—and make some pharma companies a fortune......»»
Scientists hijack natural delivery system to send engineered proteins to target cells
Each cell in the body has its own unique delivery system that scientists are working on harnessing to move revolutionary biological drugs—molecules like proteins, RNA and combinations of the two—to specific diseased parts of the body......»»
Discovery of daphnane diterpenoids in Daphne pedunculata could lead to new HIV drugs
A research group led by Professor Wei Li of the Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Toho University, in collaboration with Shenyang Pharmaceutical University in China and Duke University Medical Center in the United State.....»»
FruitFlow: A new citizen science initiative unlocks orchard secrets
The "FruitWatch" initiative, a groundbreaking citizen science project, has significantly enhanced the accuracy of predicting flowering times for fruit trees across Great Britain. This improvement is vital for the agricultural sector, enabling better.....»»
De-risking drug discovery with predictive AI
Developing a new drug can take years of research and cost millions of dollars. Still, more than 90% of drug candidates fail in clinical trials, with even more that never make it to the clinical stage. Many drugs fail because they simply aren't safe......»»
Enzyme-powered "snot bots" help deliver drugs in sticky situations
Snot might not be the first place you'd expect nanobots to be swimming around. But this slimy secretion exists in more places than just your nose and piles of dirty tissues—it also lines and helps protect the lungs, stomach, intestines and eyes. An.....»»
Research team develops method to design safer opioids
Opioid medications offer people relief from debilitating pain, but these drugs come with dangers: the risk for addiction, miserable withdrawal symptoms and the potential for fatal overdose. In a study appearing in ACS Central Science, researchers hav.....»»
Harnessing big data helps scientists hone in on new antimicrobials
Researchers have developed a strategy to identify new antimicrobial drugs with therapeutic promise from bacterial datasets, providing clues for discovering alternatives to traditional antibiotics......»»
Researchers develop library for RNA-based therapeutic approaches with polymer nanoparticles
RNA therapy with polymer nanoparticles is considered a promising approach for the treatment of various illnesses. It involves the use of polymers as "nanocarriers" to transport RNA drugs precisely to the correct target cells. Manufacturing such polym.....»»
Research team develops light-activated compounds to treat neuropathic pain
Light can be used to activate drugs in specific parts of the body through photopharmacology. This innovative approach involves modifying the chemical structure of a drug by adding a light-activated molecular switch, such as azobenzene. This allows th.....»»
It’s Shockingly Easy to Buy Off-Brand Ozempic Online, Even If You Don’t Need It
Weight-loss drugs like Ozempic are in shortage, and telehealth startups are selling “compounded” versions. A WIRED investigation looks at how easy it is to order these meds online......»»