Unfreezing waters in ligand binding sites to aid in drug discovery
Cryogenic (frozen) protein structures are central to understanding function and developing drugs. Scientists at St. Jude Children's Research Hospital have created an algorithm to reveal when freezing the proteins may create "artifacts,"—errors that.....»»
A comprehensive derivative synthesis method for development of new antimicrobial drugs
Efforts to combat the increasing threat of drug-resistant bacteria are being assisted by a new approach for streamlining the search for antimicrobial drug candidates, pioneered by researchers at Hokkaido University, led by Assistant Professor Kazuki.....»»
Astronomers discover dozens of double-lined double white dwarf binaries
An international team of astronomers reports the discovery of 34 rare double-lined double white dwarf binary systems using the Intermediate-dispersion Spectrograph and Imaging System (ISIS) on the William Herschel Telescope (WHT). The finding was det.....»»
Discovery Of Lagoon In Argentina That Could Provide "Earliest Signs Of Life" On Earth
Discovery Of Lagoon In Argentina That Could Provide "Earliest Signs Of Life" On Earth.....»»
Mars likely had cold and icy past, new study finds
The question of whether Mars ever supported life has captivated the imagination of scientists and the public for decades. Central to the discovery is gaining insight into the past climate of Earth's neighbor: Was the planet warm and wet, with seas an.....»»
Surfing NASA"s internet of animals: Satellites study ocean wildlife
Anchoring the boat in a sandbar, research scientist Morgan Gilmour steps into the shallows and is immediately surrounded by sharks. The warm waters around the tropical island act as a reef shark nursery, and these baby biters are curious about the ne.....»»
A new species of extinct crocodile relative rewrites life on the Triassic coastline
The surprising discovery of a new species of extinct crocodile relative from the Triassic Favret Formation of Nevada, U.S., rewrites the story of life along the coasts during the first act of the Age of Dinosaurs......»»
Lion with nine lives breaks record with longest swim in predator-infested waters
A record-breaking swim by two lion brothers across a predator-infested African river has been documented in a study co-led by Griffith University and Northern Arizona University......»»
Why Hurricane Beryl Underwent Unprecedented Rapid Intensification
Hurricane Beryl, the earliest Category 5 storm in the Atlantic, exploded in strength unusually early in its development, fueled by exceptionally warm ocean waters.....»»
What Makes a Psychedelic Experience? Not Always a Drug, It Turns Out
A Stanford anesthesiologist deconstructs the component parts of what it means to undergo a psychedelic trip.....»»
We’re Not Asking the Right Question to Solve the Overdose Crisis
Drug policy continues to fixate on symptoms rather than the actual disease.....»»
Quantum Xchange CipherInsights enhancements identify weaknesses in enterprise cryptography
Quantum Xchange announced the latest release of CipherInsights, the company’s network monitoring, crypto-discovery and risk assessment tool. Version 11.0 includes several new features to pinpoint any weaknesses in enterprise cryptography and ease a.....»»
Latest tvOS 18 beta lockscreen find points to long-rumored Apple home hub
Continuing rumors that Apple will launch a new home device have been further backed up by the discovery of a hidden touchscreen interface in tvOS 18 beta 3.An artist's rendition of a HomePod with a displayApple is treating what it refers to as "Audio.....»»
Using microwave sintering to produce "space brick" for a future moon base
The recent discovery of energy resources on the moon, such as water ice, has refocused interest on its potential as a sustainable hub for space exploration. NASA has also announced the Artemis mission, aiming for long-term human presence on the lunar.....»»
Drug middlemen inflate US prices, squeeze out competition, FTC says
Pharmacy benefit managers (PBMs) are key part of US's high drug costs, report finds. Enlarge / Lina Khan, chair of the Federal Trade Commission (FTC), testifies before the House Appropriations Subcommittee at the Rayburn House O.....»»
The next Intel desktop chips may muddy the AI waters
Intel's upcoming Arrow Lake-S desktop processors are said to be very lacking in one key area, but that might not matter at all......»»
New weight-loss and diabetes drugs linked to lower risk of 10 cancers
For diabetes patients, GLP-1 drugs linked to lower cancer risks compared to insulin. Enlarge / Ozempic is a GLP-1 drug for adults with type 2 diabetes. (credit: Getty | Steve Christo) For patients with Type 2 diabetes, t.....»»
"Sacrifice" of virus data clears the path to open a disease discovery pipeline
Tens of millions of still-unknown or misunderstood viruses can cause diseases—including new pandemics—and affect the health of valuable terrestrial and marine environments......»»
First set of rational design principles for chaotropic membrane transporters
The challenge of internalizing impermeable molecules into cells persists in drug development, particularly concerning water-soluble bioactive compounds that cannot diffuse across the cell membrane. To overcome this problem, various artificial transpo.....»»
New discovery boosts bioethanol production efficiency and profits
A new technique to monitor contamination in bioethanol production could increase revenue by more than $1.6 billion USD and reduce CO2 emissions by 2 million tons......»»
Swarms of orbiting sensors could map an asteroid"s surface
It seems like every month a new story appears announcing the discovery of thousands of new asteroids. Tracking these small body objects from ground and even space-based telescopes helps follow their overall trajectory. But understanding what they're.....»»