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Unfreezing waters in ligand binding sites to aid in drug discovery

Cryogenic (frozen) protein structures are central to understanding function and developing drugs. Scientists at St. Jude Children's Research Hospital have created an algorithm to reveal when freezing the proteins may create "artifacts,"—errors that.....»»

Category: topSource:  physorgJun 7th, 2022

More bad news for psychedelic drug company: FDA expands probe after rejection

Psychedelic drug company Lykos already slashed staff and overhauled leadership. Enlarge / President of Multidisciplinary Association for Psychedelic Studies (MAPS) Rick Doblin speaks onstage during the 2023 Concordia Annual Sum.....»»

Category: topSource:  arstechnicaRelated NewsAug 27th, 2024

Discovery of a hidden epigenetic clock in mitochondria reveals a "lifespan limit line"

Building on their work on epigenetics of aging and transposable elements, researchers Dr. Ádám Sturm and Dr. Tibor Vellai from Eötvös Loránd University have made another advance in understanding the molecular mechanisms of aging. Their latest st.....»»

Category: topSource:  physorgRelated NewsAug 26th, 2024

Telegram CEO Pavel Durov awaits charges in France as firm denies law-breaking

Telegram accused of not cooperating on drug trafficking and child sexual content. Enlarge / Pavel Durov, CEO and co-founder of Telegram, speaks at TechCrunch Disrupt SF 2015 on September 21, 2015, in San Francisco, California. (c.....»»

Category: topSource:  arstechnicaRelated NewsAug 26th, 2024

Floods ease in Bangladesh but 300,000 still in shelters

River waters in low-lying Bangladesh are receding after days of deadly floods but 300,000 people are still in emergency shelters requiring aid, disaster officials said Sunday......»»

Category: topSource:  physorgRelated NewsAug 25th, 2024

Experts meet as final global plastic treaty talks near

With months until crunch talks on the world's first binding treaty on plastic pollution, experts are meeting in Bangkok to discuss financing options and problematic plastics......»»

Category: topSource:  physorgRelated NewsAug 24th, 2024

Germany plans $3.7 billion program to help decarbonize industry, including carbon storage

The German government on Friday announced plans to provide about 3.3 billion euros ($3.7 billion) in funding for projects to make industry more climate-friendly, including by storing carbon dioxide underground at offshore sites......»»

Category: topSource:  physorgRelated NewsAug 23rd, 2024

Canadian government intervenes in railway labor dispute

Federal Labor Minister Steven MacKinnon to use powers under Section 107 of the Labor Code to ask the Canada Industrial Relations Board to impose final, binding arbitration.....»»

Category: topSource:  autonewsRelated NewsAug 23rd, 2024

FDA green-lights fall COVID-19 boosters

Updated mRNA vaccines from Pfizer and Moderna are ready to roll. Enlarge (credit: Getty Images) As the COVID-19 case count continues to tick upward, the US Food and Drug Administration has approved an updated vaccine for.....»»

Category: topSource:  arstechnicaRelated NewsAug 23rd, 2024

Engineers design lookalike drug nanocarrier to evade lung"s lines of defense

A drug-carrying molecule designed to cure disease by slipping past the lung's natural defenses offers new hope for people with chronic or deadly respiratory diseases, say its creators, researchers in assistant professor Liheng Cai's Soft Biomatter La.....»»

Category: topSource:  pcmagRelated NewsAug 22nd, 2024

From coal plant to data center: Old power stations are being repurposed

Industrial sites have the large tracts of land and resources needed. Enlarge (credit: Robert Nickelsberg/Getty Images) Booming demand for artificial intelligence is encouraging big tech companies and their suppliers to e.....»»

Category: topSource:  arstechnicaRelated NewsAug 22nd, 2024

Unveiling glycoRNAs: New study proves they do exist

In a groundbreaking exploration of cell surface biology, Ryan Flynn has uncovered a surprising role for RNA outside the confines of the cell. Flynn's research, which focuses on the biology of cell surface RNA, led to the discovery that certain RNAs a.....»»

Category: topSource:  physorgRelated NewsAug 21st, 2024

MeerKAT observations detect a mysterious faint radio ring

An international team of astronomers reports a serendipitous discovery of a new radio ring toward the Galactic center. The newfound object is relatively faint and its true nature is yet unknown. The finding was reported in a research paper forthcomin.....»»

Category: topSource:  physorgRelated NewsAug 21st, 2024

AI accelerates discovery of next-gen polymers

Nylon, Teflon, Kevlar. These are just a few familiar polymers—large-molecule chemical compounds—that have changed the world. From Teflon-coated frying pans to 3D printing, polymers are vital to creating the systems that make the world function be.....»»

Category: topSource:  physorgRelated NewsAug 20th, 2024

This year’s summer COVID wave is big; FDA may green-light COVID shots early

Wastewater SARS-CoV-2 levels suggest the summer surge is high and peaking right now. Enlarge (credit: Getty | Thomas Trutschel) With the country experiencing a relatively large summer wave of COVID-19, the Food and Drug.....»»

Category: topSource:  arstechnicaRelated NewsAug 20th, 2024

Researchers track the sub-Antarctic journey of two Australian pygmy blue whales

An epic journey spanning thousands of kilometers from Indonesia deep into sub-Antarctic waters by two Australian pygmy blue whales has been tracked by researchers for the first time, confirming a long-held hypothesis about the travel habits of the su.....»»

Category: topSource:  physorgRelated NewsAug 19th, 2024

UK diving team hail suspected WWI warship find

A team of UK divers has hailed the discovery of a wreck off Scotland believed to be a Royal Navy warship sunk during World War I but still "virtually intact"......»»

Category: topSource:  pcmagRelated NewsAug 18th, 2024

Max: HBO Max replacement, price, movies, TV shows, devices, and more

Here's everything you need to know about Max, Warner Bros Discovery's super streamer replacement for HBO Max......»»

Category: topSource:  theglobeandmailRelated NewsAug 17th, 2024

Urban Birds Are Harboring Antibiotic-Resistant Bacteria

Exposure to bacteria in landfill sites and polluted rivers may explain prevalence among city-dwelling birds......»»

Category: gadgetSource:  wiredRelated NewsAug 17th, 2024

Geophysicists find link between seismic waves called PKP precursors and strange anomalies in Earth"s mantle

For the decades since their discovery, seismic signals known as PKP precursors have challenged scientists. Regions of Earth's lower mantle scatter incoming seismic waves, which return to the surface as PKP waves at differing speeds......»»

Category: topSource:  physorgRelated NewsAug 17th, 2024

Popular AI “nudify” sites sued amid shocking rise in victims globally

“Nudify” sites may be fined for making it easy to “see anyone naked,” suit says. Enlarge (credit: Viktoriya Skorikova | Moment) San Francisco's city attorney David Chiu is suing to shut down 16 of the most popula.....»»

Category: topSource:  arstechnicaRelated NewsAug 16th, 2024