Unfreezing waters in ligand binding sites to aid in drug discovery
Cryogenic (frozen) protein structures are central to understanding function and developing drugs. Scientists at St. Jude Children's Research Hospital have created an algorithm to reveal when freezing the proteins may create "artifacts,"—errors that.....»»
Study combines data and molecular simulations to accelerate drug discovery
Researchers from the University of Cincinnati College of Medicine and Cincinnati Children's Hospital have found a new method to increase both speed and success rates in drug discovery......»»
Claw machine games are Rio de Janeiro"s new public enemy
Rio de Janeiro—already notorious for street muggings, corrupt politicians, ruthless militias and Kalashnikov-toting drug traffickers—has a new public enemy: plushies. Or, more specifically, the joystick-controlled claw machines that dispense them.....»»
Sign in with Apple was available on multiple deepfake nudes sites
Sign in with Apple was launched back in 2019 as a faster, more convenient, and privacy-focused way of registering with an app or website. But a new report says that it was being offered by multiple deepfake nudes sites. The inclusion of sign-in op.....»»
Eli Lilly raises price of Zepbound while trumpeting discount on starter vials
Cost for insured patients without coverage for the drug rises from $550 to $650 a month. Enlarge / An Eli Lilly & Co. Zepbound injection pen arranged in the Brooklyn borough of New York, US, on Thursday, March 28, 2024. (credit:.....»»
MPA says no more “Whac-a-Mole” with pirate sites, claims it took down “mothership”
Fmovies takedown "is a stunning victory," MPA CEO Charles Rivkin said. Enlarge / Motion Picture Association CEO Charles Rivkin speaks onstage during CinemaCon, a convention of the National Association of Theatre Owners, at Caesar.....»»
Uncovering the secret communication of marmoset monkeys: They have names
A new study from Hebrew University reveals that marmoset monkeys use specific calls, known as "phee-calls," to name each other, a behavior previously known to exist only in humans, dolphins, and elephants. This discovery highlights the complexity of.....»»
Tuberculosis under the sea: A marine sponge microbe provides insights into the bacterium"s evolution
The surprising discovery of a bacterium in a marine sponge from the Great Barrier Reef with striking similarity to Mycobacterium tuberculosis, the pathogen responsible for tuberculosis (TB), could unlock and inform future TB research and treatment st.....»»
Like people, vultures get set in their ways and have fewer friends as they age
If you'd rather be watching TV on your couch than dancing at the club, you might have something in common with aging griffon vultures. New research shows that young griffon vultures move frequently between sleeping sites in different locations and in.....»»
Neutron scattering instrument represents a new dawn for AI-powered atomic-scale 3D imaging
The Department of Energy's Oak Ridge National Laboratory added a new neutron scattering instrument to its powerhouse of discovery at the Spallation Neutron Source, charting new territory for neutron imaging through artificial intelligence. In July, D.....»»
Scientists discover how starfish get "legless"
Researchers at Queen Mary University of London have made a discovery about how starfish manage to survive predatory attacks by shedding their own limbs. The team has identified a neurohormone responsible for triggering this remarkable feat of self-pr.....»»
Study reveals crucial role of mixing Atlantic and Arctic waters in global ocean circulation
A new study sheds light on the vital role that the mixing of Atlantic and Arctic waters plays in sustaining the Atlantic Meridional Overturning Circulation (AMOC), which is crucial for regulating Earth's climate......»»
Teens recognize risk behavior in movies and series, but are not always critical
When teens see risk behavior such as drinking, smoking or drug use in movies or series, they sometimes find it difficult to define whether it's realistic or not. They recognize stereotypes but cannot always interpret it critically. This is according.....»»
RISCPoint RADAR provides real-time vulnerability detection across multiple attack surfaces
RISCPoint Advisory Group launched RADAR, an all-in-one cybersecurity platform. Combining continuous threat discovery with expert-led Penetration Testing as a Service (PTaaS), RADAR represents a significant leap forward in proactive security and risk.....»»
Study finds flexibility and helical twists of actin filaments regulate actin-binding proteins
Researchers at Kanazawa University have published an article in eLife deciphering the actin structure-dependent preferential cooperative binding of cofilin......»»
DNA replication in early embryos differs from previous assumptions, study shows
A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the experiments published August 28 in Nature show that DNA repl.....»»
Promising Mpox Drug Fails in Trials as Virus Spreads
In a trial in the Democratic Republic of the Congo, the drug tecovirimat, also known as TPOXX, was found to be no better than placebo at clearing mpox lesions......»»
Discovery explains the chemistry behind the cell"s energy molecule
An international research team led by Professor Magnus Wolf-Watz at Umeå University has discovered how the magnesium atom directs the chemistry that catalyzes the production of the energy molecule ATP in a cell. The study is published in the journal.....»»
Cybercriminals capitalize on travel industry’s peak season
Cybercriminals are capitalizing on the travel and hospitality industry’s peak season, using increased traffic as cover for their attacks, according to Cequence Security. Researchers investigated the top 10 travel and hospitality sites to identi.....»»
Wood charcoal reveals the existence of a variety of woody plants around early millet sites
A study led by Hui Shen, Keliang Zhao, Xinying Zhou, Xiaoqiang Li from the Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, and Zhenwei Qiu from the National Museum of China has reconstructed how early millet f.....»»
Towards a large materials model for AI-driven materials discovery
Following the success of large language models, the concept of large materials models as deep-learning computational models for materials design has attracted great interest. Nevertheless, the task of acquiring large materials models appears to be qu.....»»