Uncovering previously unexplored cellular mechanisms
Single-cell and spatially resolved omics have helped scientists take a closer look at tissue composition, structure, and function. This comprehensive understanding paves the way for them to uncover some intricate and previously unknown disease mechan.....»»
JP Clausen brings auto, tech experience to GM manufacturing
JP Clausen, who previously worked for Tesla, Google and Lego, joined GM in April to succeed the retiring Gerald Johnson executive vice president of global manufacturing and sustainability......»»
What a submerged ancient bridge discovered in a Spanish cave reveals about early human settlement
A new study led by the University of South Florida has shed light on the human colonization of the western Mediterranean, revealing that humans settled there much earlier than previously believed. This research, detailed in a recent issue of the jour.....»»
AI tool maps out cell metabolism with precision
Understanding how cells process nutrients and produce energy—collectively known as metabolism—is essential in biology. Modern biology generates large datasets on various cellular activities, but integrating and analyzing the vast amounts of data.....»»
Light-activated polymerization methods unlock new possibilities for intracellular applications
Synthetic polymers play a crucial role in cell biology, serving as delivery vehicles for DNA and drugs, acting as fluorescent probes for cellular sensing, functioning as bioinks for tissue engineering, and mimicking biological functionality (e.g., ar.....»»
Uncovering the secret communication of marmoset monkeys: They have names
A new study from Hebrew University reveals that marmoset monkeys use specific calls, known as "phee-calls," to name each other, a behavior previously known to exist only in humans, dolphins, and elephants. This discovery highlights the complexity of.....»»
Scientists unlock the secrets of how a key protein converts DNA into RNA
Researchers at the Department of Energy's SLAC National Accelerator Laboratory have uncovered new insights into the fundamental mechanisms of RNA polymerase II (Pol II), the protein responsible for transcribing DNA into RNA. Their study shows how the.....»»
International consortium with NASA reveals hidden impact of spaceflight on gut health
Scientists have uncovered how spaceflight profoundly alters the gut microbiome, revealing previously unknown effects on host physiology that could shape the future of long-duration space missions......»»
Shedding light on the mechanism of yeast DNA repair
DNA damage is a cellular phenomenon that introduces structural abnormalities in double-stranded DNA. External factors, such as radiation or chemical agents, as well as internal factors, such as blocked DNA replication, can generate double-strand brea.....»»
AI company Midjourney teases hardware product in a new form factor
It hired a hardware chief who previously worked on Apple Vision Pro. Responding to this meme image of a wizard with an orb from the I.C.E. book Middle-earth: Valar and Maiar, Midjourney's founder joked that the new hardware form.....»»
AI image-generation company Midjourney says it’s “getting into hardware”
It hired a hardware chief who previously worked on Apple Vision Pro. Responding to this meme image of a wizard with an orb from the I.C.E. book Middle-earth: Valar and Maiar, Midjourney's founder joked that the new hardware form.....»»
Simulation model shows ribosome tunnel"s impact on protein structures
Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations, they have analyzed the structures of various proteins within t.....»»
Light microscopy study reveals molecular density changes during mitotic chromosome condensation
A team of scientists studying cell division developed a special light microscopy system and used it to analyze the molecular density of cellular environments. Their results provide a novel insight into mitotic chromosome condensation in living human.....»»
Gaps in firearms relinquishment laws may weaken court orders, increase illegal gun possession
State and federal laws across the United States prohibiting firearm possession in cases of domestic violence often lack enforcement mechanisms, which may lead to continued possession of firearms despite court orders, according to a University of Mich.....»»
The deadly cost of workplace rudeness: Study highlight adverse effects on team performance
Teams from the University of Florida, Indiana University, and other universities across the U.S. and Israel recently conducted five eye-opening studies about rudeness, uncovering that even mild instances of this behavior can significantly impair empl.....»»
Scientists use evolution to bioengineer new pathways to sustainable energy and pharmaceuticals
Using evolution as a guiding principle, researchers have successfully engineered bacteria-yeast hybrids to perform photosynthetic carbon assimilation, generate cellular energy and support yeast growth without traditional carbon feedstocks like glucos.....»»
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that assembles under conditions of genotoxic stress. Des.....»»
Discovery of a hidden epigenetic clock in mitochondria reveals a "lifespan limit line"
Building on their work on epigenetics of aging and transposable elements, researchers Dr. Ádám Sturm and Dr. Tibor Vellai from Eötvös Loránd University have made another advance in understanding the molecular mechanisms of aging. Their latest st.....»»
3D shapes of viral proteins point to previously unknown roles
Viruses are tricky to keep up with. They evolve quickly and regularly develop new proteins that help them infect their hosts. These rapid shifts mean that researchers are still trying to understand a multitude of viral proteins and precisely how they.....»»
From antiquity to adaptation: Tracing the genetic journey of east Asian chestnut varieties
Uncovering the genetic saga of Castanea trees, a study maps their evolutionary journey and local climate adaptations. This research reveals the genetic markers and molecular mechanisms that have allowed these nut fruit trees to adapt and flourish acr.....»»
A hybrid arrowhead against immune disorders: Bacterially derived natural product inhibits cellular immune response
The so-called immunoproteasome is essential for the cellular immune response. In autoimmune diseases, however, it is overactive. Until now, it has not been possible to selectively inhibit the immunoproteasome without disrupting other cellular mechani.....»»