Ticks Are Spreading in the US—and Taking New Diseases With Them
The vast majority of tick-borne disease goes unrecorded, meaning life-threatening pathogens are traveling under the radar to new locations......»»
Scientists learn how to drug wily class of disease-causing enzymes
UCSF scientists have discovered how to target a class of molecular switches called GTPases that are involved in a myriad of diseases from Parkinson's to cancer and have long been thought to be "undruggable.".....»»
The Mosquito-Borne Disease ‘Triple E’ Is Spreading in the US as Temperatures Rise
Eastern equine encephalitis, which has a high mortality rate, is becoming more common in North America as climate changes expands the habitats of insects......»»
Solving the side effect problem of siRNA drugs for genetic disease treatment
Small interfering RNA (siRNA) drugs are a class of therapeutic agents that silence specific genes associated with inherited diseases. However, siRNA drugs have challenges because siRNAs often silence genes other than the target ones, causing side eff.....»»
Global experts present early-stage recommendations for nanomedicine development
They're tiny drug-delivery systems 1,000 times smaller than a human hair, but while nanomedicines have long been hailed as the future for treating debilitating and life-threatening diseases, their journey from lab to patient has many challenges......»»
Unveiling the molecular mechanisms linking aging with neurodegenerative diseases
Aging is the prime cause of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. But what exactly increases the prevalence of these brain disorders as one grows older? The molecular forces l.....»»
Avian flu has infected dairy cows in more than a dozen states—a microbiologist explains how the virus is spreading
The current strain of avian flu, H5N1, is responsible for the culling of millions of domestic birds and has sickened more than a dozen farmworkers in 2024, most recently in Colorado......»»
Researchers map 50,000 of DNA"s mysterious "knots" in the human genome
Researchers have mapped 50,000 of DNA's mysterious "knots" in the human genome. The innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer......»»
STEM program for middle- and high-school girls inspires brilliance
In a classroom on Georgia State's Atlanta Campus, more than a dozen middle and high school girls are wearing lab coats and peering into test tubes. They're conducting an epidemiology experiment—the study of how diseases are spread. It's just one of.....»»
Closing the RNA loop holds promise for more stable, effective RNA therapies
New methods to shape RNA molecules into circles could lead to more effective and long-lasting therapies, shows a study by researchers at the University of California San Diego. The advance holds promise for a range of diseases, offering a more enduri.....»»
A hybrid arrowhead against immune disorders: Bacterially derived natural product inhibits cellular immune response
The so-called immunoproteasome is essential for the cellular immune response. In autoimmune diseases, however, it is overactive. Until now, it has not been possible to selectively inhibit the immunoproteasome without disrupting other cellular mechani.....»»
Mapping the sex life of malaria parasites at single cell resolution reveals genetics underlying transmission
Malaria is caused by a eukaryotic microbe of the Plasmodium genus, and is responsible for more deaths than all other parasitic diseases combined. In order to transmit from the human host to the mosquito vector, the parasite has to differentiate into.....»»
Adversaries love bots, short-lived IP addresses, out-of-band domains
Fastly found 91% of cyberattacks – up from 69% in 2023 – targeted multiple customers using mass scanning techniques to uncover and exploit software vulnerabilities, revealing an alarming trend in attacks spreading across a broader target base. In.....»»
Mosquitoes sense infrared from body heat to help track humans down, study shows
While a mosquito bite is often no more than a temporary bother, in many parts of the world it can be scary. One mosquito species, Aedes aegypti, spreads the viruses that cause over 100,000,000 cases of dengue, yellow fever, Zika and other diseases ev.....»»
Engineers design lookalike drug nanocarrier to evade lung"s lines of defense
A drug-carrying molecule designed to cure disease by slipping past the lung's natural defenses offers new hope for people with chronic or deadly respiratory diseases, say its creators, researchers in assistant professor Liheng Cai's Soft Biomatter La.....»»
Town urges curfew over mosquito-spread disease that kills up to 50% of people
Eastern Equine Encephalitis is very rare in the US, but when it strikes, it's bad. Enlarge / A mosquito collected to test for mosquito-borne diseases. (credit: Getty | Jon Cherry) A small town in Massachusetts is urging.....»»
Novel carbon nanohorn-based treatment enables efficient delivery of drugs in cancer therapy
Cancer remains one of the most challenging diseases to treat due to its complexity and tendency to metastasize (spread into, or invade, nearby tissues or distant places in the body to form new tumors). Traditional therapies, such as chemotherapy and.....»»
Honey bees may play key role in spreading viruses to wild bumble bees
Honey bees may play a role in increasing virus levels in wild bumble bees each spring, according to researchers at Penn State who analyzed seasonal trends of parasite and virus transmission in bees......»»
Study finds "DNA scavengers" can stop some antibiotic resistance from spreading
For nearly a century, scientists have waged war on antibiotic-resistant microbes. Michigan State University researchers say they've found a new way to prevent it—by unleashing "DNA scavengers" in wastewater treatment plants......»»
Roundworm study paves way for better RNA-based drugs to treat human disease
RNA interference (RNAi) therapeutics have garnered significant attention in clinical research due to their potential for treating various diseases, including genetic disorders, viral infections and cancer. These therapeutics can target and silence di.....»»
Brazil fishermen turn to mobile app to combat pollution scourge
Brazilian activist and fisherman Alexandre Anderson uses one hand to steer his boat, and the other to film an oil stain spreading over Rio de Janeiro's Guanabara Bay......»»